Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

D-Lysine monohydrochloride

D-Lysine monohydrochloride is an Lysine stereoisomer which can be used as a component of surfactants[1].

  • CAS Number: 7274-88-6
  • MF: C6H15ClN2O2
  • MW: 182.648
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 311.5ºC at 760 mmHg
  • Melting Point: 266ºC (dec.)
  • Flash Point: 142.2ºC

Boc-D-tyrosine

Boc-D-Tyr-OH is a tyrosine derivative[1].

  • CAS Number: 70642-86-3
  • MF: C14H19NO5
  • MW: 281.304
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 484.9±40.0 °C at 760 mmHg
  • Melting Point: 135-140 °C
  • Flash Point: 247.1±27.3 °C

Lauroylcholine Chloride Hydrate

Lauroylcholine Chloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 25234-60-0
  • MF: C17H36ClNO2
  • MW: 321.926
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 206-208°C
  • Flash Point: N/A

2-(Methyl-d3)phenol

2-(Methyl-d3)phenol is the deuterium labeled 2-(Methyl)phenol[1].

  • CAS Number: 70837-27-3
  • MF: C7H5D3O
  • MW: 111.15600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cy3 maleimide chloride

Cy3 maleimide chloride is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing maleimide functional groups. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The alkyne functional group of Cy3 maleimide chloride can undergo a "thiol-acrylamide" reaction with molecules containing sulfur-oxygen functional groups to form covalent bonds. Cy3 maleimide chloride can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.

  • CAS Number: 1838643-41-6
  • MF: C36H43ClN4O3
  • MW: 615.22
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Type A Allatostatin II

Allatostatin II is a decapeptid amine. Allatostatins are pleiotropic neuropeptides for inhibition of juvenile hormone synthesis in insects.

  • CAS Number: 123374-34-5
  • MF: C49H74N14O13
  • MW: 1067.20
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Olmesartan ethyl ester

Olmesartan ethyl ester (compound 11) is an Olmesartan impurity. Olmesartan (RNH-6270) is an angiotensin II receptor (AT1R) antagonist used to in the high blood pressure study[1].

  • CAS Number: 144689-23-6
  • MF: C26H30N6O3
  • MW: 474.55500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Wilfordine

Wilfordine is an alkaloid that isolated from the roots of Tripterygium wilfordii[1].

  • CAS Number: 37239-51-3
  • MF: C43H49NO19
  • MW: 883.844
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 895.5±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 495.4±34.3 °C

5,6-Dichlorovanillin

5,6-Dichlorovanillin is a product upon chlorination to afford 4,5,6-trichloroguaiacol, together with tetrachloroguaiacol and the unreacted starting materials[1].

  • CAS Number: 18268-69-4
  • MF: C8H6Cl2O3
  • MW: 221.037
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 313.9±37.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 143.7±26.5 °C

1-Hydroxyrutaecarpine

1-Hydroxyrutaecarpine (compound 1a) is a hydroxy-derivative of rutaecarpine. 1-Hydroxyrutaecarpine shows cytotoxicities with ED50s of 3.72, 7.44 µg/mL for P-388 and HT-29 cells, respectively. 1-Hydroxyrutaecarpine shows antiplatelet activity[1][2][3].

  • CAS Number: 53600-24-1
  • MF: C18H13N3O2
  • MW: 303.31
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 601.7±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 317.7±34.3 °C

5-HT2A receptor agonist-3

5-HT2A receptor agonist-3 is the most selective agonist for the human 5-HT2A receptor yet discovered, with a Ki of 2.5 nM, and with 124-fold selectivity for 5-HT2A over the structurally similar 5-HT2C receptor[1].

  • CAS Number: 1391499-52-7
  • MF: C21H26BrNO3
  • MW: 420.34
  • Catalog: 5-HT Receptor
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

EIDD-1931-d2

EIDD-1931-d2 is the deuterium labeled 3,6-Dichloro-2-methoxybenzoic acid[1].

  • CAS Number: 1955549-12-8
  • MF: C9H11D2N3O6
  • MW: 261.23
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N6-[((1S,2R)-1-CARBOXY-2-HYDROXYBUTYLAMINO)CARBONYL]ADENOSINE SODIUM SALT

N6 - Threonylcarbamoyladenosine is a common nucleosides, which can decorate and become tRNA[1].

  • CAS Number: 24719-82-2
  • MF: C15H19N6NaO8
  • MW: 434.33700
  • Catalog: Others
  • Density: 1.96g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

DACN(Tos,Suc-NHS)

DACN(Tos,Suc-NHS) is a click chemistry reagent containing an azide group.

  • CAS Number: 2411082-26-1
  • MF: C22H25N3O7S
  • MW: 475.51
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2,3,5-Trimethylphenol

2,3,5-Trimethylphenol is a phenolic compound[1].

  • CAS Number: 697-82-5
  • MF: C9H12O
  • MW: 136.19
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 231.1±9.0 °C at 760 mmHg
  • Melting Point: 92-95 °C(lit.)
  • Flash Point: 103.6±8.4 °C

Sulfameter-d4

Sulfameter-d4 (Sulfametoxydiazine-d4; 5-Methoxysulfadiazine-d4)is the deuterium labeledSulfameter(HY-B0213)[1]. Sulfameter (Sulfametoxydiazine; 5-Methoxysulfadiazine) is an effective long-acting sulfonamide antibiotic with antibacterial activities. Sulfameter can be used for the research of urinary tract infections and lepriasis[2].

  • CAS Number: 1189483-96-2
  • MF: C11H8D4N4O3S
  • MW: 284.33
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

VU0483605

VU0483605 is a potent and brain-penetrated mGlu1 receptor positive allosteric modulator (PAM). VU0483605 shows excellent mGlu1 PAM activity at both human and rat, with EC50 values of 390 and 356 nM, respectively[1].

  • CAS Number: 1623101-11-0
  • MF: C20H10Cl3N3O3
  • MW: 446.67
  • Catalog: mGluR
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Colfosceril palmitate

DPPC is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers.

  • CAS Number: 63-89-8
  • MF: C40H80NO8P
  • MW: 734.039
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 229-229.5 °C
  • Flash Point: N/A

[4aR,(-)]-4,4a,5,6,7,8-Hexahydro-1,4aα-dimethyl-7β-(1-methylethenyl)naphthalene-2(3H)-one

(-)-10-epi-α-Cyperone (Compound 3) is a biochemical reagent[1].

  • CAS Number: 2303-31-3
  • MF: C15H22O
  • MW: 218.33
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Broxaterol

Broxaterol (Z 1170) is the an agonist of β2 adrenergic receptor that affects the smooth muscle receptors in the body. Broxaterol plays an important role in respiratory disease[1].

  • CAS Number: 76596-57-1
  • MF: C9H15BrN2O2
  • MW: 263.13200
  • Catalog: Adrenergic Receptor
  • Density: 1.402g/cm3
  • Boiling Point: 370.5ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 177.9ºC

diisoamylamine

Diisoamylamine (Diisopentylamine) is a small molecule that can be used for wet etching[1].

  • CAS Number: 544-00-3
  • MF: C10H23N
  • MW: 157.29600
  • Catalog: Others
  • Density: 0,767 g/cm3
  • Boiling Point: 187-188°C
  • Melting Point: -44°C
  • Flash Point: 58°C

fmoc-l-cyclopropylalanine

Fmoc-β-cyclopropyl-L-Alanine is an alanine derivative[1].

  • CAS Number: 214750-76-2
  • MF: C21H21NO4
  • MW: 351.396
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 547.5±29.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 284.9±24.3 °C

1,8-Dihydroxy-2,3,5-trimethoxy-9H-xanthen-9-one

Angustin A (1,8-Dihydroxy-4,6,7-trimethoxyxanthone) is a xanthones that can be isolated from the aerial parts of Swertia angustifolia[1].

  • CAS Number: 1415795-50-4
  • MF: C16H14O7
  • MW: 318.278
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 572.5±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 216.1±23.6 °C

3'-azido-3'-deoxy-5'-O-beta-glucopyranuronosylthymidine

Zidovudine O-β-D-glucuronide (3'-Azido-3'-deoxythymidine β-D-glucuronide) sodium is the major metabolite of Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection[1][2].

  • CAS Number: 117675-21-5
  • MF: C16H21N5O10
  • MW: 443.37
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3’-Azido-3’-deoxy-5-fluorouridine

3’-Azido-3’-deoxy-5-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

  • CAS Number: 307520-05-4
  • MF: C9H10FN5O5
  • MW: 287.20
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

7-Methylguanine

7-Methylguanine is a metabolite of DNA methylation. It can be generated by methylating agents, and used as a probe of protein–DNA interactions and a key component of DNA sequencing method.

  • CAS Number: 578-76-7
  • MF: C6H7N5O
  • MW: 165.153
  • Catalog: Others
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: 481.4±37.0 °C at 760 mmHg
  • Melting Point: 370°C
  • Flash Point: 244.9±26.5 °C

Conifegrol

O-Geranylconiferyl alcohol is a sesquiterpenoids? isolated from? the root of Ligularia duciformis[1].

  • CAS Number: 129350-09-0
  • MF: C20H28O3
  • MW: 316.43
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 469.9±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 238.0±28.7 °C

Orotidine 5′-monophosphate

Orotidine 5′-monophosphate is a pyrimidine ribonucleoside and plays a role as an endogenous metabolite of human, E. coli or mouse. Orotidine 5′-monophosphate is an intermediate in the biosynthesis of uridine monophosphate (UMP). Orotidine 5′-monophosphate can be used for the study of mechanism of orotidine 5′-monophosphate decarboxylase[1][2].

  • CAS Number: 2149-82-8
  • MF: C10H13N2O11P
  • MW: 368.19
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Tergitol

Tergitol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • Density: 1.056 g/mL at 25 °C
  • Boiling Point: >200 °C(lit.)
  • Melting Point: N/A
  • Flash Point: >230 °F

5-Hydroxy-4',7-dimethoxy-6,8-dimethylflavone

Eucalyptin is a flavonoid. Eucalyptin can be isolated from Myrcia citrifolia[1].

  • CAS Number: 3122-88-1
  • MF: C19H18O5
  • MW: 326.343
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 539.5±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 196.4±23.6 °C