Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Aristola-1(10),8-dien-2-one

Aristola-1(10),8-dien-2-one is a sesquiterpene compound that can be isolated from rhizome of Nardostachys chinensis of Valerianaceae[1].

  • CAS Number: 22391-34-0
  • MF: C15H20O
  • MW: 216.32
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

alpha-Amylase

Bacterial α-Amylase catalyses the hydrolysis of internal α-1,4-glycosidic linkages in starch in low molecular weight products, such glucose, maltose and maltotriose units. Bacterial α-Amylase is often used in biochemical studies[1].

  • CAS Number: 9000-85-5
  • MF: C31H27NO4
  • MW: 477.550
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 643.1±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 342.7±31.5 °C

Isoguaiacin

Isoguaiacin is a natural product[1].

  • CAS Number: 78341-26-1
  • MF: C20H24O4
  • MW: 328.4
  • Catalog: Others
  • Density: 1.151±0.06 g/cm3(Predicted)
  • Boiling Point: 484.5±45.0 °C(Predicted)
  • Melting Point: 198-200 °C
  • Flash Point: N/A

Carbamazepine 10,11-epoxide-13C

Carbamazepine 10,11-epoxide-13C is the 13C labeled Carbamazepine 10,11-epoxide (HY-W013378)[1].

  • CAS Number: 67411-80-7
  • MF: C1413CH12N2O2
  • MW: 253.26
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BTTAA-OH

BTTAA-OH is a kind of tris(triazolylmethyl)amine compound. BTTAA-OH has the potential for the research of labeling and/or imaging in living system (extracted from patent WO2012021390A1)[1].

  • CAS Number: 1257633-69-4
  • MF: C19H32N10O
  • MW: 416.52400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Cys-Asp-Pro-Gly-Tyr-Ile-Gly-Ser-Arg-OH trifluoroacetate salt

Laminin (925-933) is a peptide derived from residues 925-933 of the Laminin B1 chain that binds to the laminin receptor[1].

  • CAS Number: 110590-60-8
  • MF: C40H62N12O14S
  • MW: 967.06
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-[(2'-Cyano[1,1'-biphenyl]-4-yl)methyl]-L-valine methyl ester hydrochloride

(S)-Methyl 2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)-3-methylbutanoate hydrochloride is a valine derivative[1].

  • CAS Number: 482577-59-3
  • MF: C20H23ClN2O2
  • MW: 358.862
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 186ºC
  • Flash Point: N/A

Germacrene D

(Rac)-Germacrene D is a racemate of Germacrene D. Germacrene D has antibacterial and antifungal activities and can be used as an adjuvant agent in the application of aminoglycosides and azoles[1].

  • CAS Number: 37839-63-7
  • MF: C15H24
  • MW: 204.35
  • Catalog: Others
  • Density: 0.85g/cm3
  • Boiling Point: 279.7ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 111.9ºC

Endovion

Endovion (NS3728) is a pharmacological anion channel inhibitor (like chloride channel) and the specific VRAC/VSOAC blocker. Endovion (NS3728) is also an Anoctamin-1 (ANO 1) channel inhibitor[1][2].

  • CAS Number: 265646-85-3
  • MF: C16H9BrF6N6O
  • MW: 495.18
  • Catalog: Chloride Channel
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N6-Methyladenosine N1-oxide

N6-Methyladenosine N1-oxide is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

  • CAS Number: 113509-54-9
  • MF: C11H15N5O5
  • MW: 297.27
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Methyl (9Z)-12-acetoxy-9-octadecenoate

Methyl O-Acetylricinoleate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 140-03-4
  • MF: C21H38O4
  • MW: 354.524
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 428.5±38.0 °C at 760 mmHg
  • Melting Point: -26ºC
  • Flash Point: 200.1±25.2 °C

Dansyl Ethylenediamine

Dansyl ethylenediamine is a fluorescent probe. Dansyl ethylenediamine can be used for synthesis of protein-imprinted polymers which is capable of specific transduction of protein binding events into fluorescent signal change[1].

  • CAS Number: 35060-08-3
  • MF: C14H19N3O2S
  • MW: 293.38500
  • Catalog: Others
  • Density: 1.262g/cm3
  • Boiling Point: 470.2ºC at 760mmHg
  • Melting Point: 145-146ºC
  • Flash Point: 238.1ºC

Acetylatractylodinol

Acetylatractylodinol, isolated from Atractylodes lancea, possesses antioxidant activity[1].

  • CAS Number: 61582-39-6
  • MF: C15H14O4
  • MW: 258.26900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Acotiamide hydrochloride

Acotiamide hydrochloride is an orally active, selective and reversible acetylcholinesterase (AChE) inhibitor, with IC50 of 1.79 μM. Acotiamide hydrochloride can enhance gastric contractility and accelerate delayed gastric emptying. Acotiamide hydrochloride has the potential for the research of functional dyspepsia involving gastric motility dysfunction and intestinal inflammatory[1][2][3].

  • CAS Number: 185104-11-4
  • MF: C21H31ClN4O5S
  • MW: 487.013
  • Catalog: AChE
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

BF 844

BF 844 (BioFocus 844) is a small molecules capable of stabilizing mutant USH3 mutation CLRN1(N48K); effectively attenuated progressive hearing loss and prevented deafness in mouse model potentially prevents both sensory deficiencies in patients with USH3.

  • CAS Number: 1404506-35-9
  • MF: C21H19ClN4O
  • MW: 378.85
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-Thr(tBu)-OPfp

Fmoc-Thr(tBu)-OPfp is a threonine derivative[1].

  • CAS Number: 117088-31-0
  • MF: C29H26F5NO5
  • MW: 563.51200
  • Catalog: Others
  • Density: 1.329g/cm3
  • Boiling Point: 632.5ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 336.3ºC

Lactobionic Acid Calcium Salt

Calcium Lactobionate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 5001-51-4
  • MF: C24H42CaO24
  • MW: 754.654
  • Catalog: Others
  • Density: 1.79g/cm3
  • Boiling Point: 864.7ºC at 760mmHg
  • Melting Point: ~190 °C (dec.)
  • Flash Point: 319.1ºC

Nimucitinib

Nimucitinib is a Janus kinase (JAK) inhibitor[1].

  • CAS Number: 2740557-24-6
  • MF: C25H26F2N6O2
  • MW: 480.51
  • Catalog: JAK
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-Methylphenol acetate

m-Tolyl acetate is a intermediate of organic synthesis.

  • CAS Number: 122-46-3
  • MF: C9H10O2
  • MW: 150.17400
  • Catalog: Others
  • Density: 1.04 g/mL at 25 °C(lit.)
  • Boiling Point: 210-213 °C(lit.)
  • Melting Point: N/A
  • Flash Point: 203 °F

1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d9

1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d9 is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glyc

  • CAS Number: 326495-36-7
  • MF: C44H79D9NO8P
  • MW: 799.20
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

WAY-325811

WAY-325811 is an active molecule.

  • CAS Number: 869632-12-2
  • MF: C18H18N2O2S
  • MW: 326.41
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cloransulam-methyl

Cloransulam-methyl is a triazolopyrimidine sulfonanilide herbicide. Cloransulam-methyl can be used to control broadleaf weeds in soybean by acetolactate synthase (ALS) inhibition[1].

  • CAS Number: 147150-35-4
  • MF: C15H13ClFN5O5S
  • MW: 429.81100
  • Catalog: Others
  • Density: 1.65g/cm3
  • Boiling Point: N/A
  • Melting Point: 216-218ºC
  • Flash Point: N/A

17:0-22:4 PC-d5

17:0-22:4 PC-d5 is deuterium labeled 17:0-22:4 PC.

  • CAS Number: 2342575-43-1
  • MF: C47H81D5NO8P
  • MW: 829.19
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Mycophenolic acid D3

Mycophenolic acid D3 is deuterium labeled Mycophenolic acid, which is an an immunosuppresant drug and has potent anti-proliferative activity.

  • CAS Number: 1185242-90-3
  • MF: C17H17D3O6
  • MW: 323.35600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 132-134°C
  • Flash Point: 2℃

N-Eicosane-d42

N-Eicosane-d42 is the deuterium labeled N-Eicosane[1].

  • CAS Number: 62369-67-9
  • MF: C20D42
  • MW: 324.80600
  • Catalog: Others
  • Density: 0.905g/cm3
  • Boiling Point: 220ºC30 mm Hg(lit.)
  • Melting Point: 36-38ºC(lit.)
  • Flash Point: >230 °F

2H-1-Benzopyran-2-one,3-acetyl-6-bromo-

3-Acetyl-6-bromocoumarin is a coumarin. 3-Acetyl-6-bromocoumarin exhibites potent antioxidant activity at 56%[1].

  • CAS Number: 2199-93-1
  • MF: C11H7BrO3
  • MW: 267.07500
  • Catalog: Others
  • Density: 1.643g/cm3
  • Boiling Point: 441.3ºC at 760mmHg
  • Melting Point: 227ºC
  • Flash Point: 220.7ºC

1-OCTADECANOYL-2-[CIS-9-OCTADECENOYL]-SN-GLYCERO-3-PHOSPHOCHOLINE

2-Oleoyl-1-stearoyl-sn-glycero-3-phosphocholine (1-Stearoyl-2-oleoyl-sn-glycero-3-PC) is an active compound. 2-Oleoyl-1-stearoyl-sn-glycero-3-phosphocholinecan be used for various biochemical studies[1].

  • CAS Number: 56421-10-4
  • MF: C44H86NO8P
  • MW: 788.13
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Z-Pro-OH

Carbobenzoxyproline (L-Cbz-Proline) is an inhibitor of prolidase. Carbobenzoxyproline can be used for prolidase deficiency (PD) research[1].

  • CAS Number: 1148-11-4
  • MF: C13H15NO4
  • MW: 249.262
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 432.3±45.0 °C at 760 mmHg
  • Melting Point: 76-78ºC
  • Flash Point: 215.3±28.7 °C

Coelenterazine 400a (hydrochloride)

Coelenteramine 400a (Coelenterazine 400a) hydrochloride, a derivative of Coelenterazine, is a Renilla luciferase (RLuc) substrate. In the presence of Coelenteramine 400a hydrochloride, RLuc can emit blue light at 395 nm[1][2]. Coelenteramine 400a hydrochloride will causes color change in the bioluminescence reaction of Rluc by replacing the sulfur and oxygen heteroatoms of the methylene bridge. Coelenteramine 400a hydrochloride provides higher signal resolution and can be used in the research of bioluminescence resonance energy transfer (BRET)[3].

  • CAS Number: 2320429-05-6
  • MF: C26H22ClN3O
  • MW: 427.925
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Rutarin

Rutarin is a Coumarin (HY-N0709) derivative, that can be isolated from the aerial parts of the plant Atalantta racemosa[1].

  • CAS Number: 20320-81-4
  • MF: C20H24O10
  • MW: 424.40
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 726.5±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 258.4±26.4 °C