3-O-Sulfo-D-galactosyl-β1-1'-N-tridecanoyl-D-erythro-sphingosine-d7 is deuterium labeled 3-O-Sulfo-D-galactosyl-β1-1'-N-tridecanoyl-D-erythro-sphingosine.
HKOH-1r is a highly sensitive and selective fluorescent probe which is used for detecting endogenous hydroxyl radicals in living cells[1].
CDK5-IN-2 (compound 15) is a highly selective CDK5 inhibitor with IC50s of 0.2 and 23 for CDK5/p25 and CDK2/CycA, respectively[1].
TWS119 TFA is a specific inhibitor of GSK-3β, with an IC50 of 30 nM, and activates the wnt/β-catenin pathway.
Fmoc-HoCys(ACM)-OH, a homolog of cysteine, is synthesized from L-methionine. Fmoc-HoCys(ACM)-OH also can be used for the synthesis of solid phase peptide[1].
trans-Zeatinriboside-d5 is the deuterium labeled trans-Zeatinriboside (HY-W011151). trans-Zeatinriboside is a type of cytokinin precursor, acts as a major long-distance signalling form in xylem vessels, regulates leaf size and meristem activity-related traits[1][2].
2-Hydroxypinocembrin is a 2-hydroxyflavanones substrate of flavonoid C-glycosyltransferases[1].
15,16-Di-O-acetyldarutoside (compound 5) is an ent-pimarane diterpenoid compound isolated from the ethanol extract of Siegesbeckia orientalis[1].
Norcaesalpinin E is a natural cassane-type diterpene found in the seed kernels of Caesalpinia crista[1].
4-Allyltoluene, an aromatic compound, can elicite antennal olfactory response of Mediterranean fruit fly measured by electroantennography (EAG)[1].
Cholesteryl dodecanoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
3,4-Difluoro-L-phenylalanine is a phenylalanine derivative[1].
L-Methionine is the L-isomer of Methionine, an essential amino acid for human development. Methionine acts as a hepatoprotectant.
N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyldimethylsilyl)-L-serine is a serine derivative[1].
Sortin1 is a chemical genetic-hit molecule that causes specific mislocalization of plant and yeast-soluble and membrane vacuolar markers.IC50 value:Target: Vacuolar markersin vitro: In Arabidopsis seedlings, application of Sortin1 and -2 led to reversible defects in vacuole biogenesis and root development. Sortin1 was found to redirect the vacuolar destination of plant carboxypeptidase Y and other proteins in Arabidopsis suspension cells and cause these proteins to be secreted. Sortin1 treatment of whole Arabidopsis seedlings also resulted in carboxypeptidase Y secretion, indicating that the drug has a similar mode of action in cells and intact plants [1]. Structure-activity relationship studies conducted in Arabidopsis revealed the structural requirements for Sortin1 bioactivity and demonstrated that overlapping Sortin1 substructures can be used to discriminate between vacuolar-flavonoid accumulations and vacuolar-biogenesis defects [2].
Iminodiacetic acid (IDA) is a chelating agent that strongly binds transition metals[1]. Iminodiacetic acid can be used for removal of toxic metal ions from water[2]. Iminodiacetic acid can serve as a biomarker to potentially predict the severity of ARDS (acute respiratory distress syndrome)[3].
Gefitinib impurity 1 is the impurity of Gefitinib. Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity[1][2].
N-(Methylsulfonyl)glycine is a Glycine (HY-Y0966) derivative[1].
(4α,11β,15β)-11,15-Dihydroxykaur-16-en-19-oic acid is a compound isolated from the Tunisian Pulicaria laciniata (Coss.et Kral.) Thell. flowers[1].
6-Methoxyquinoline is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N-(2,4-dimethoxybenzyl)glycine is a Glycine (HY-Y0966) derivative[1].
Dimethyl-DL-2,3-distearoyloxypropyl(2-hydroxyethyl)ammonium (acetate) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Lactoferricin H, Lactotransferrin (37-61), human is a biological active peptide. (This is an antimicrobial peptide derived from human lactotransferrin amino acid residues 37-61.)
Murralongin is a nature product. Murralongin can be isolated from the leaves of Galipea panamensis[1].
Tinnevellin glucoside, a naphthalene glycoside, isolated from Cassia senna leaves and pods[1].
Nε-Carbobenzoxy-Nα-tosyl-L-lysine is a lysine derivative[1].
3α,4β-Galactotriose is a galactosyl residue[1].
Deoxyribonucleic acid is a polymer made of two polynucleotide chains wrapped around each other to form a double helix. Deoxyribonucleic acid is found in all dividing cells and is an essential constituent of the chromosomes[1].
p,p'-DDD-d8 is the deuterium labeled p,p'-DDD[1]. p,p'-DDD is a major metabolite of p,p'-DDT. p,p'-DDD occurs in the feces and livers of rats, that are given p,p'-DDT by stomach tube, but not of rats injected intraperitoneally with p,p'-DDT[2][3].