Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

H-PHG-OMEHCL

(S)-(+)-2-Phenylglycine methyl ester hydrochloride is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 15028-39-4
  • MF: C9H12ClNO2
  • MW: 201.650
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 238.9ºC at 760mmHg
  • Melting Point: 200ºC (dec.)(lit.)
  • Flash Point: 104.7ºC

lauric acid n-hydroxy-succinimide ester

(2,5-Dioxopyrrolidin-1-yl) dodecanoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 14565-47-0
  • MF: C16H27NO4
  • MW: 297.39000
  • Catalog: Others
  • Density: 1.07g/cm3
  • Boiling Point: 392.3ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 191.1ºC

odoratone

Odoratone (Dehydroodoratol) has insecticidal activity (LC50: 154 ppm)[1].

  • CAS Number: 16962-90-6
  • MF: C30H48O4
  • MW: 472.700
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 571.2±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 177.5±23.6 °C

3-hydroxy-5-methoxy-3-methoxycarbonyl-5-oxo-pentanoic acid

Dimethylurea/citric acid is a highly efficient deep eutectic solvent (DES). Dimethylurea/citric acid can be used as a catalyst and a green reaction medium for the synthesis of bis(indolyl)methanes, quinolines and aryl-4, 5-diphenyl-1H-imidazoles.

  • CAS Number: 53798-97-3
  • MF: C8H12O7
  • MW: 220.17700
  • Catalog: Others
  • Density: 1.378g/cm3
  • Boiling Point: 405.1ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 162.6ºC

WSP-5

WSP-5 is a fluorescent probe for fast detection of H2S in biological samples and cells. WSP-5 selectively and rapidly reacts with H2S and exhibits fluorescence through a reaction-based fluorescent turn-on strategy.

  • CAS Number: 1593024-78-2
  • MF: C44H26N2O7S4
  • MW: 822.95
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sarpagan-17-ol

(19Z)-Normacusine B, Gelsemiurn alkaloids, is a natural product that can be isolated from Gelsemiurn[1].

  • CAS Number: 124096-81-7
  • MF: C19H22N2O
  • MW: 294.39
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 472.7±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 239.7±28.7 °C

SP-Chymostatin B

SP-Chymostatin B is a potent inhibitor of many proteases, including chymotrypsin, papain, chymotrypsin-like serine proteinases, chymases, and lysosomal cysteine proteinases. It weakly inhibits human leucocyte elastase. It is effective at a final concentration of 100 to 200 μg/ml (10 to 100 μM).

  • CAS Number: 70857-49-7
  • MF: C30H41N7O6
  • MW: 595.701
  • Catalog: Elastase
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

AG-1557

AG-1557, compound 22 (T), is a ATP competitive inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase with a pIC50 value of 8.194[1].

  • CAS Number: 189290-58-2
  • MF: C16H14IN3O2
  • MW: 407.206
  • Catalog: EGFR
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 492.9±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 251.9±28.7 °C

Medronic Acid

Medronic Acid (Methylenediphosphonic acid) is a methylene-substituted bisphosphonate. Medronic acid has affinity for and adheres to the surface of hydroxyapatite crystals in the bone matrix. This agent accumulates at sites of osteoid mineralization and can be used, complexed with radioisotopes in bone imaging.

  • CAS Number: 1984-15-2
  • MF: CH6O6P2
  • MW: 176.002
  • Catalog: Others
  • Density: 2.1±0.1 g/cm3
  • Boiling Point: 583.2±60.0 °C at 760 mmHg
  • Melting Point: 197-199 °C(lit.)
  • Flash Point: 306.5±32.9 °C

Uridine-5-oxyacetic acid

Uridine-5-oxyacetic acid is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

  • CAS Number: 28144-25-4
  • MF: C11H14N2O9
  • MW: 318.24
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fl-DIBO

Fl-DIBO (fluorogenic dibenzocyclooctyne) is a selective and high sensitivity fluorescent probe to azide compounds. Fl-DIBO can react rapidly with azide compounds to form new highly fluorescent products with a maximum emission wavelength of 469 nm and excitation wavelength of 363 nm. Fl-DIBO can be used to label diazo-tagged proteins without detectable background signal interference[1][2].

  • CAS Number: 1407523-31-2
  • MF: C19H12O3
  • MW: 288.30
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

MBS Crosslinker

3-Maleimidobenzoic acid N-hydroxysuccinimide ester is used as asymmetric spacers[1].

  • CAS Number: 58626-38-3
  • MF: C15H10N2O6
  • MW: 314.250
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 524.5±52.0 °C at 760 mmHg
  • Melting Point: 175-177 °C(lit.)
  • Flash Point: 271.0±30.7 °C

(Rac)-Azide-phenylalanine

(Rac)-Azide-phenylalanine is a racemate of Azide-phenylalanine. Azide-phenylalanine is a phenylalanine derivative and a non-natural amino acid. Azide-phenylalanine can be site-specifically incorporated into proteins and used to label proteins[1].

  • CAS Number: 1822572-56-4
  • MF: C9H10N4O2
  • MW: 206.20
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

IR5790

IR5790 is a herbicide. IR5790 strongly inhibits protoporphyrinogen oxidase with an IC50 of 3 nM[1].

  • CAS Number: 192809-26-0
  • MF: C15H14Cl2N2O2S
  • MW: 357.25
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

hCAIX/XII-IN-4

hCAIX/XII-IN-4 (compound 6c) is a potent CAIX/XII inhibitor with the Ki values of 4.5 nM, 23.6 nM, >10000 nM and >10000 nM for CAXII, CAIX, CAI and CAⅡ, respectively[1].

  • CAS Number: 1119200-33-7
  • MF: C20H16N2O5
  • MW: 364.35
  • Catalog: Carbonic Anhydrase
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Biotin-PEG8-Me-Tet

Biotin-PEG8-Me-Tet is a biotin labeling.

  • CAS Number: 2143958-82-9
  • MF: C39H62N8O11S
  • MW: 851.02
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ethyl pentadecanoate

Ethyl Pentadecanoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 41114-00-5
  • MF: C17H34O2
  • MW: 270.451
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 314.0±5.0 °C at 760 mmHg
  • Melting Point: 12-14 °C
  • Flash Point: 142.2±7.5 °C

4-Hydroxyindole

4-Hydroxyindole is a member of the class of hydroxyindoles that is 1H-indole substituted by a hydroxy group at position 4. 4-Hydroxyindole is an important raw material or intermediate in the synthesis of pharmaceutical products and industrial polymers[1].

  • CAS Number: 2380-94-1
  • MF: C8H7NO
  • MW: 133.147
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 343.2±15.0 °C at 760 mmHg
  • Melting Point: 97-99 °C(lit.)
  • Flash Point: 161.4±20.4 °C

(R)-Rivastigmine (D6 tartrate)

(R)-Rivastigmine D6 (tartrate) is the deuterium labeled (R)-Rivastigmine, which is an cholinesterase inhibitor.

  • CAS Number: 194930-00-2
  • MF: C18H22D6N2O8
  • MW: 406.46000
  • Catalog: AChE
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Meso-Tetra(4-tert-butylphenyl) Porphine

meso-Tetra(4-tert-butylphenyl) porphine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 110452-48-7
  • MF: C60H62N4
  • MW: 839.16
  • Catalog: Others
  • Density: 1.108g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-n-me-arg(mtr)-oh

N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-Nw-((4-methoxy-2,3,6-trimethylphenyl)sulfonyl)-N2-methyl-L-arginine is an arginine derivative[1].

  • CAS Number: 214750-72-8
  • MF: C32H38N4O7S
  • MW: 622.73200
  • Catalog: Others
  • Density: 1.32
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

acetyl ethyl carbinol

3-Hydroxypentan-2-one, natural product, can be isolated from Carambola (Averrhoa carambola L. )[1].

  • CAS Number: 3142-66-3
  • MF: C5H10O2
  • MW: 102.13200
  • Catalog: Others
  • Density: 0.962g/cm3
  • Boiling Point: 147.5ºC at 760mmHg
  • Melting Point: 2.5°C (estimate)
  • Flash Point: 53.8ºC

8-Benzyloxyadenosine

8-Benzyloxyadenosine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

  • CAS Number: 131265-29-7
  • MF: C17H19N5O5
  • MW: 373.36
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sibiricose A5

Sibiricose A5 is an oligosaccharide ester isolated from Polygalae Radix with potent antioxidant activity[1][2].

  • CAS Number: 107912-97-0
  • MF: C22H30O14
  • MW: 518.465
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 821.7±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 279.7±27.8 °C

coprine

Coprine is a mycotoxin isolated from Coprinopsis atramentaria. Coprine is an acetaldehyde dehydrogenase inhibitor that causes the buildup of acetaldehyde, causing the alcohol flushing reaction[1].

  • CAS Number: 58919-61-2
  • MF: C8H14N2O4
  • MW: 202.20800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

trans-2-Undecenoic acid

trans-2-Undecenoic acid ((E)-2-Undecenoic acid) is an α,β-unsaturated carboxylic acid and is characterized by acid dimers. The corresponding dimers are connected via intermolecular hydrogen bonds of the carboxylic groups C=O···H-O[1].

  • CAS Number: 15790-94-0
  • MF: C11H20O2
  • MW: 184.27500
  • Catalog: Others
  • Density: 0.929g/cm3
  • Boiling Point: 295.4ºC at 760mmHg
  • Melting Point: 8.5 °C(estimate)
  • Flash Point: 201.1ºC

LHRH (chicken) trifluoroacetate salt

[Gln8]-C517 (LH-RH), chicken is an avian hypothalamic peptide, which stimulates release of gonadotropins from anterior pituitary, thus regulating reproductive functions.

  • CAS Number: 47922-48-5
  • MF: C54H71N15O14
  • MW: 1154.23000
  • Catalog: Others
  • Density: 1.398g/cm3
  • Boiling Point: 1812ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 1049.7ºC

4-Decenoic acid

4-Decenoic Acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 26303-90-2
  • MF: C10H18O2
  • MW: 170.24900
  • Catalog: Others
  • Density: 1.182g/cm3
  • Boiling Point: 177.8ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 65ºC

(4R)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-1-methyl-D-proline

(4R)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-1-methyl-D-proline is a proline derivative[1].

  • CAS Number: 1946010-90-7
  • MF: C11H20N2O4
  • MW: 244.2875
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 388.9±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 189.0±27.9 °C

N3-Gly-Gly-Gly-Gly-Gly-OH

N3-Gly-Gly-Gly-Gly-Gly-OH is a click chemistry reagent containing an azide group.

  • CAS Number: 2250433-77-1
  • MF: C10H15N7O6
  • MW: 329.27
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A