Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Isocucurbitacin D

Isocucurbitacin D is an antitumor agent[1].

  • CAS Number: 68422-20-8
  • MF: C30H44O7
  • MW: 516.66600
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Methyl chlorogenate

Methyl chlorogenate is an antioxidant, and has radical scavenging activity. Methyl chlorogenate is an anti-inflammatory agent. Methyl chlorogenate also inhibits hepatocellular carcinoma (HCC) cell proliferation and metastasis[1][2].

  • CAS Number: 29708-87-0
  • MF: C17H20O9
  • MW: 368.34
  • Catalog: Cancer
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 577.0±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 208.1±23.6 °C

Gastrodin

Gastrodin, a main constituent of a Chinese herbal medicine Tianma, has been known to display anti-inflammatory effects. Gastrodin, has long been used for treating dizziness, epilepsy, stroke and dementia.

  • CAS Number: 62499-27-8
  • MF: C13H18O7
  • MW: 286.278
  • Catalog: Inflammation/Immunology
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 563.2±50.0 °C at 760 mmHg
  • Melting Point: 154-157ºC
  • Flash Point: 294.4±30.1 °C

Boc-Hyp-Oet

Boc-Hyp-OEt is a proline derivative[1].

  • CAS Number: 37813-30-2
  • MF: C12H21NO5
  • MW: 259.29900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

SAR629

SAR629 is a potent monoglyceride lipase (MGL) covalent inhibitor. SAR629 also inhibits 2-Arachidonoylglycerol (2-AG) degradation[1][2].

  • CAS Number: 1221418-42-3
  • MF: C20H19F2N5O
  • MW: 383.39
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Mapatumumab

Mapatumumab (HGS-ETR1) is a fully human IgG1 agonistic monoclonal antibody that targets tumor necrosis factor-related apoptosis-inducing ligand receptor 1 (TRAIL-R1). Mapatumumab can be used for the research of cancer[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

LU-005i

LU-005i is a potent inhibitor of β5i subunit of immunoproteasomes (IC50 = 6.6 nM), selective over β5c subunit (IC50 = 287 nM)[1].

  • CAS Number: 1620107-33-6
  • MF: C31H46N4O7
  • MW: 586.72
  • Catalog: Inflammation/Immunology
  • Density: 1.189±0.06 g/cm3(Predicted)
  • Boiling Point: 860.2±65.0 °C(Predicted)
  • Melting Point: N/A
  • Flash Point: N/A

Hydrocortisone buteprate

Hydrocortisone buteprate (Hydrocortisone probutate) is a medium potent, non-halogenated double-ester of hydrocortisone with a favorable benefit/risk ratio for the treatment of inflammatory skin disorders. Hydrocortisone buteprate (Hydrocortisone probutate) is available as a 0.1% cream or ointment formulation[1].

  • CAS Number: 72590-77-3
  • MF: C28H40O7
  • MW: 488.61300
  • Catalog: Inflammation/Immunology
  • Density: 1.2g/cm3
  • Boiling Point: 608.9ºC at 760 mmHg
  • Melting Point: 122ºC
  • Flash Point: 194.7ºC

2-Oxo-2H-pyran-5-carboxylic acid

Coumalic acid is a valuable platform compound which can be prepared from malic acid. Coumalic acid can be used in the flavours, fragrances and cosmetics industries, as polymer components, and as pharmaceutical scaffolds displaying anti-bronchial and -malarial activity[1].

  • CAS Number: 500-05-0
  • MF: C6H4O4
  • MW: 140.094
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 282.4±0.0 °C at 760 mmHg
  • Melting Point: 203-205 °C (dec.)(lit.)
  • Flash Point: 137.3±19.4 °C

β,β-Dimethylacrylalkannin

(Rac)-Arnebin 1 ((Rac)-β,β-Dimethylacrylalkannin) is the racemate of β,β-Dimethylacrylalkannin and/or β,β-Dimethylacrylshikonin. β,β-Dimethylacrylalkannin and β,β-Dimethylacrylshikonin are napthoquinones isolated from Arnebia nobilis. β,β-Dimethylacrylshikonin has anti-tumor activity[1].

  • CAS Number: 5162-01-6
  • MF: C21H22O6
  • MW: 370.39600
  • Catalog: Others
  • Density: 1.269g/cm3
  • Boiling Point: 587.345 °C
  • Melting Point: N/A
  • Flash Point: 206.409 °C

eupatolitin

Eupatoletin is a flavonol compound isolated from Eupatorium ligustrinum D.C.[1].

  • CAS Number: 29536-44-5
  • MF: C17H14O8
  • MW: 346.28800
  • Catalog: Others
  • Density: 1.591g/cm3
  • Boiling Point: 640ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 238.7ºC

cyanidin

Cyanidin, an antioxidant, has protective effect on DNA cleavage, free radical scavenging activity and significant inhibition of XO activity[1].

  • CAS Number: 13306-05-3
  • MF: C15H11O6
  • MW: 287.244
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Netupitant N-Oxide

Netupitant N-oxide is the metabolite of Netupitant, which is a highly selective NK1 receptor antagonist.

  • CAS Number: 910808-11-6
  • MF: C30H32F6N4O2
  • MW: 594.59100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Beauveriolide III

Beauveriolide III is an inhibitor of lipid droplet formation in mouse macrophages[1].

  • CAS Number: 221111-70-2
  • MF: C27H41N3O5
  • MW: 487.632
  • Catalog: Metabolic Disease
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 777.3±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 423.9±32.9 °C

Jacquilenin

Jacquilenin is a natural product that can be isolated from the flowers of Picris hieracioides L.[1].

  • CAS Number: 7726-34-3
  • MF: C15H18O4
  • MW: 262.30100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium

1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium is a ubstitute for Phosphoserine/phosphatidylserine. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium can be used in lipid mixtures with DOPC and DOPE as effective nontoxic and nonviral DNA vectors[1].

  • CAS Number: 90693-88-2
  • MF: C42H77NNaO10P
  • MW: 811.03300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Mebendazole-d3

Mebendazole-d3 is the deuterium labeled L-Methionine-34S[1].

  • CAS Number: 1173021-87-8
  • MF: C16H10D3N3O3
  • MW: 298.31
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5-Hydroxycytosine-13C,15N2

5-Hydroxycytosine-13C,15N2 is the 13C and 15N labeled 5-Hydroxycytosine[1].

  • CAS Number: 181516-92-7
  • MF: C313CH5N15N2O2
  • MW: 130.08
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Exendin-3 trifluoroacetate salt

Exendin-3 is a biologically active peptides isolated from venoms of the Gila monster lizards, Heloderma horridurn .

  • CAS Number: 130357-25-4
  • MF: C184H282N50O61S
  • MW: 4202.57
  • Catalog: Peptides
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1,1'-Diethyl-2,2'-carbocyanine iodide

Pinacyanol iodide is a fluorescent cyanine dye. Pinacyanol iodide exhibits ultrafast excited state isomerization[1].

  • CAS Number: 605-91-4
  • MF: C25H25IN2
  • MW: 480.384
  • Catalog: Others
  • Density: 1.151g/cm3
  • Boiling Point: 527.7ºC at 760 mmHg
  • Melting Point: 295 °C (dec.)(lit.)
  • Flash Point: 240.2ºC

2,3-Dihydroxy-3-(4-hydroxyphenyl)propanoic acid

3-Hydroxy-3-(4-hydroxyphenyl)-lactic acid is a key metabolite in the P. roqueforti fermentation approach, with quantitative data of 10.2 ± 1.1 µM in Tyr1 (presence of L-tyrosine) of [1].

  • CAS Number: 100201-57-8
  • MF: C9H10O5
  • MW: 198.17
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 489.8±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 264.1±25.2 °C

Trx-red

Trx-red (NBL-SS perchlorate) is a red-emitting fluorescent probe derivatized from the nile blue fluorophore. Trx-red is used for selectively imaging thioredoxin (Trx) in live cells and in vivo (λex=615 nm, λem=661 nm)[1].

  • CAS Number: 2368978-96-3
  • MF: C29H32ClN3O12S2
  • MW: 714.16
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

MPG peptides, Pβ

MPG peptides, Pβ is a primary amphiphilic peptide consisting of three domains[1].

  • CAS Number: 791642-10-9
  • MF: C129H208N36O32S
  • MW: 2807.32
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

boc-(s)-alpha-benzyl-proline

Boc-(S)-α-benzyl-Pro-OH is a proline derivative[1].

  • CAS Number: 706806-61-3
  • MF: C17H23NO4
  • MW: 305.36900
  • Catalog: Others
  • Density: 1.193g/cm3
  • Boiling Point: 443.1ºC at 760 mmHg
  • Melting Point: 146℃
  • Flash Point: 221.8ºC

Gatralimab

Gatralimab (GZ-402668) is an IgG1 anti-CD52 monoclonal antibody[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-Glu-OtBu

Boc-Glu-OtBu is a glutamic acid derivative[1].

  • CAS Number: 24277-39-2
  • MF: C14H25NO6
  • MW: 303.351
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 449.8±40.0 °C at 760 mmHg
  • Melting Point: 113 °C
  • Flash Point: 225.8±27.3 °C

7-Methyl-6-thioguanosine

MESG is a chromophoric substrate which can be used for the quantitation of inorganic phosphate.

  • CAS Number: 55727-10-1
  • MF: C11H15N5O4S
  • MW: 313.333
  • Catalog: Dye Reagents
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: >175ºC (dec.)
  • Flash Point: N/A

Pirinixil

Pirinixil is a hypolipidemic agent of low toxicity.

  • CAS Number: 65089-17-0
  • MF: C16H19ClN4O2S
  • MW: 366.86600
  • Catalog: Metabolic Disease
  • Density: 1.37g/cm3
  • Boiling Point: 609.6ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 322.5ºC

Aplodan

Aplodan is an antiischemic and antiarrhythmic agent. Aplodan has a protective action on cell membrane. Aplodan has the potential for the research of ischemic heart or ischemic heart disease with persistent ventricular premature beats (VPB) [1][2].

  • CAS Number: 6903-79-3
  • MF: C4H12N3O4P
  • MW: 197.130
  • Catalog: Cardiovascular Disease
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 384.1±52.0 °C at 760 mmHg
  • Melting Point: 244 °C(dec.)
  • Flash Point: 186.1±30.7 °C

Thymohydroquinone

Thymohydroquinone is a monoterpene molecule. Thymohydroquinone has antioxidant and anti-inflammatory properties. Thymohydroquinone can be used for pharmacokinetic studies and regulatory toxicity studies [1].

  • CAS Number: 2217-60-9
  • MF: C10H14O2
  • MW: 166.22
  • Catalog: Inflammation/Immunology
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 306.4±37.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 147.9±21.1 °C