(S,S)-Pisatin (compound 8) is a dimeric pterocarpan derivative is isolated from the grains of millettia pachyloba[1][2].
N-(4-Fluoro-1,3-benzothiazol-2-yl)-N-methylglycine is a Glycine (HY-Y0966) derivative[1].
Witepsol is a selective lipid-based vehicle for use in drug delivery systems[1].
2-Amino-3-mercaptopropanoic acid is a cysteine derivative[1].
4-Fluorobenzoyl-2,3,5,6-d4 chloride is the deuterium labeled 4-Fluorobenzoyl chloride[1].
Subelliptenone G is a simple oxygenated xanthone that can be isolated from the root bark of Garcinia subelliptica[1].
Thiamine nitrate is an essential vitamin which can enhance normal neuronal actives.
Physcion (Parietin) is an anthraquinone isolated from traditional Chinese medicine Radix et Rhizoma Rhei, acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC50 and a Kd of 38.5 μM and 26.0 μM, respectively[1][2]. Physcion (Parietin) exhibits laxative, hepatoprotective, anti-inflammatory, anti-microbial, anti-proliferative and anti-tumor effects[2].
Aflatoxin G1 is one type of aflatoxins occuring in nature. It is produced by molds, such as Aspergillus flavus and Aspergillus parasiticus. Aflatoxins are hepatogenic, teratogenic, imunosuppressive, and carcinogenic fungal metabolites found in feeds, nuts, wine-grapes, spices, and other grain crops[1][2].
Ppicolinic-3,4,5,6-d4 acid is the deuterium labeled Ppicolinic acid[1].
6-FAM-PEG3-Azide is a fluorescent dye that can be used to label oligonucleotide[1].
Eicosapentaenoic acid methyl ester is a degradant of a monogalactosyl diacylglycerol (an anticancer compound by inducing apoptosis)[1].
KRN5 is a Nuclear factor of activated T cells 5 (NFAT5) suppressor, with an IC50 of 750 nM.
GRK5-IN-2 (compound 707), a pyridine-based bicyclic compound, is a potent G-protein-coupled receptor kinase 5 (GRK5) inhibitor. GRK5-IN-2 regulates the expression and/or release of insulin and is useful for the metabolic disease research[1].
ABL127 is a selective and covalent inhibitor of protein methylesterase 1 (PME-1) with IC50s of 6.4 nM and 4.2 nM in HEK293T and MDA-MB-231 cells, respectively.
Tiopronin is a prescription thiol drug used to control the rate of cystine precipitation and excretion in the disease cystinuria.Target: OthersTiopronin is used primarily for cystinuria and is well known in the cystinuric community. Depending on the severity of a person's cystinuria, tiopronin may be taken for life, possibly starting in early childhood. It may also be used for Wilson's disease (an overload of copper in the body), and certain types of rare arthritis, though tiopronin is not an anti-inflammatory. Tiopronin is also sometimes used as a stabilizing agent for metal nanoparticles. The thiol group binds to the nanoparticles, preventing coagulation [1, 2].
Ipriflavone is a synthetic isoflavone derivative used to suppress bone resorption.
Akt/SKG Substrate Peptide is a synthetic peptide suitable as a substrate for Akt/PKB, which is not phosphorylated by p70S6K or MAPK1[1].
Arctiol is a natural product that can be found in Podocarpus fleuryi[1].
SRT 1720 Hydrochloride is a selective activator of SIRT1 with an EC1.5 of 0.16 μM, and shows less potent activities on SIRT2 and SIRT3 with EC1.5s of 37 μM and 300 μM, respectively.
Implitapide Racemate is the racemate of Implitapide. Implitapide is a microsomal triglyceride transfer protein (MTP) inhibitor.
Endotoxin Substrate (Boc-LGR-pNA) is a chromogenic substrate can be used in quantitative assays of endotoxin[1].
N,N'-Bis(2,6-dimethylphenyl)-1,4-piperazinediacetamide-d8 is the deuterium labeled N,N'-Bis(2,6-dimethylphenyl)-1,4-piperazinediacetamide[1].
Furosine dihydrochloride, an amino acid derivative, is an important chemical marker of early-stage Maillard reactions. Furosine dihydrochloride is closely related to a variety of diseases such as diabetes[1][2].
N-BOC-3-Fluoro-D-phenylalanine is a phenylalanine derivative[1].
Trachelogenin 4′-O-β-gentiobioside, a lignan, can be isolated from the leaves and stems of clover[1][2].
16-o-Acetyldarutigenol (compound 4) is an ent-pimarane diterpenoid compound isolated from the ethanol extract of Siegesbeckia orientalis[1].
Lurasidone metabolite 14326 is a metabolite of Lurasidone, which is a atypical antipsychotic compound.
2′,3,5,6′,7-Pentahydroxyflavanone (compound 4) is a flavonoid compound isolated from Scutellaria baicalensis roots[1].
H-Trp-Arg-OH is a biologically active peptide.