NHS-5(6)Carboxyrhodamine is a dye used for fluorescence labeling applications, where accurate dye/protein ratios can be obtained under native conditions[1].
Fmoc-Thr-OBu-t is a threonine derivative[1].
Arabinose-d1-1 is the deuterium labeled Arabinose. Arabinose is an endogenous metabolite[1].
(Z,Z,Z)-17-Bromo-3,6,9-Heptadecatriene is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Lys-Arg-Thr-Leu-Arg-Arg (KRTLRR) is a hexapeptide. Lys-Arg-Thr-Leu-Arg-Arg is a substrate of protein kinase C from EGF receptor. Lys-Arg-Thr-Leu-Arg-Arg can be used to determine the activity of protein kinase C[1].
Thiorphan methoxyacetophenone derivative-d7 is the deuterium labeled Thiorphan methoxyacetophenone derivative[1].
N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-(tert-butylthio)-L-cysteine is a cysteine derivative[1].
Pyr-Arg-Thr-Lys-Arg-AMC TFA is a AMC peptide. AMC is a decapeptide that is specifically hydrolyzed by proteases such as trypsin and thrombin. The AMC peptide can be used to determine the activity of protease and the potency of enzyme inhibitors[1].
Keap1-Nrf2-IN-10 (compound 15) is a potent NQO1 inducer. Keap1-Nrf2-IN-10 inhibits oxidative stress by decreasing the levels of MDA, ROS, NQO1 in the liver for gamma-irradiated mice. Keap1-Nrf2-IN-10 improves the survival of gamma-irradiated mice[1].
APD 371 is a highly potent, selective and fully efficacious cannabinoid receptor type 2 (CB2) agonist, with an EC50 of 6.2 nM for hCB2.
Naringenin-4',7-diacetate (compound 13) is a pyrrolidinoflavanne isolated from the fruits of Vocbysiaguianensis[1].
1,2-O,O-Ditetradecyl-rac-glycerol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Madolin U is a germacrane sesquiterpene isolated from the herb of Viola yedoensis[1].
Methyl cis-6-Octadecenoate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Sulfo-Cyanine5.5 azide tripotassium, a near-infrared (NIR) fluorescent dye, is an azide-functionalized Sulfo-Cyanine5.5 (Ex=678 nm, Em=694 nm). Sulfo-Cyanine5.5 azide tripotassium can react with alkynes for Click Chemistry labeling[1].
Mono-n-Propyl Phthalate-3,4,5,6-d4 is the deuterium labeled Mono-n-Propyl Phthalate[1].
Drosocin is a biological active peptide. (Drosocin is a 19-mer cationic antimicrobial peptide from Drosophila melanogaster. In Drosophila native drosocin carries a disaccharide moiety attached to a threonine residue in mid-chain position. This synthetic drosocin peptide of identical amino acid sequence without the disaccharide has an activity several times lower than the native compound.)
Mequinol-d4 is the deuterium labeled Mequinol[1]. Mequinol (4-Methoxyphenol) is one of bioactive components in Mercurialis. Mequinol is used for skin depigmentation[2].
TAMRA-PEG2-Maleimide 是含有 4 个 PEG 单元的 TAMRA (HY-135640) 染料衍生物。TAMRA-PEG2-Maleimide 含有 Maleimide 基，可与硫醇基团反应形成共价键。
Catalpol, an iridoid glycoside, has neuroprotective, anti-inflammatory, and anti-hepatitis virus effects.IC50 Value:Target: neuroprotective, anti-inflammatory, and anti-hepatitis virus natural product.In vitro: Catalpol could be encapsulated into composite nanofibers and induce differentiation of hASCs into neural-like cells, which might offer new avenues in nerve regeneration [1].In vivo: The pharmacokinetics of catalpol in normal and doxorubicin-induced chronic kidney disease rats after oral administration of Rehmannia glutinosa extract was determined, and the extraction recoverie of catalpol was higher than 68.24% [2]. The protective effect of catalpol on renal IRI mice through suppressing phosphatidylinositol 3-kinase/protein kinase B (PI3K/Akt)-endothelial nitric oxide synthase (eNOS) and against inflammation, and the possible underlying mechanism [3].
P300/CBP-IN-3, a p300/CBP histone acetyltransferase inhibitor, Compound 6, is sourced from patent WO 2019049061 A1[1].
DMPA-d7 is the deuterium labeled DMPA[1].
(25S)-12β-Hydroxyspirost-4-en-3-one is a natural compound that can be isolated from Dioscorea chiupasensis[1].
bFGF (119-126) is a biological active peptide. (This peptide corresponds to human, bovine (119-126), mouse, rat (118-125) and Heparin-Binding Growth Factor 2 (118-125) residues of bFGF. It inhibits dimerization and activation of bFGF receptors.)
Carbon can be used as an excipient, such as decolorizer. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1].
Cyhalofop(Cyhalofop acid) is a recently registered herbicide from the aryloxyphenoxy propionate group in India to control a wide range of grass weed species at various growth stages in rice crop.
ATTO 425 is an uncharged fluorescent dye[1].
N-Cinnamoylpyrrole is a amide[1].
2′,3′-Anhydroadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
1,1',3,3,3',3'-Hexamethylindotricarbocyanine perchlorate (HITC) is a long-wavelength, membrane-potential sensitive dye. It is a slow-response potentiometric fluorophore and has also been used as a laser dye for infrared lasers.