Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

XF056-132

XF056-132 is the salt form of trifluoroacetic acid (TFA, HY-21182).

  • CAS Number: 2694057-55-9
  • MF: C53H58F7N9O9S
  • MW: 1130.14
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1,3,5-Tribromobenzene-d3

1,3,5-Tribromobenzene-d3 is the deuterium labeled 1,3,5-Tribromobenzene[1].

  • CAS Number: 52921-77-4
  • MF: C6Br3D3
  • MW: 317.81900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Triphenylamine-d15

Triphenylamine-d15 is the deuterium labeled Triphenylamine[1].

  • CAS Number: 880462-20-4
  • MF: C18H15N
  • MW: 245.31800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Argireline

Argireline prevents formation of skin lines and wrinkles, inhibiting neurotransmitter release at the neuromuscular junction. Sequence: N-acetyl-Glu-Glu-Met-Gln-Arg-Arg-NH2.

  • CAS Number: 616204-22-9
  • MF: C34H60N14O12S
  • MW: 888.992
  • Catalog: Peptides
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

SIRT-IN-1

SIRT-IN-1 is a potent inhibitor of SIRT1/2/3, with IC50s of 15, 10, 33 μM, respectively.

  • CAS Number: 1431411-60-7
  • MF: C19H27N5O2S
  • MW: 389.52
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Amyloid β-Protein (1-24) trifluoroacetate salt

Amyloid β-Protein (1-24) is a biologically active peptide.

  • CAS Number: 138648-77-8
  • MF: C130H183N35O40
  • MW: 2876.054
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

FMOC-Arg(Pbf)-OH

Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis)[1].

  • CAS Number: 154445-77-9
  • MF: C34H40N4O7S
  • MW: 648.769
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 132°C
  • Flash Point: N/A

4',5'-DIBROMOFLUORESCEIN

4',5'-Dibromofluorescein (Eosinic acid) is a fluorescein derivative that can used as a ligand for studying of protein properties by spectral analysis[1].

  • CAS Number: 596-03-2
  • MF: C20H10Br2O5
  • MW: 490.09800
  • Catalog: Others
  • Density: 2.1 g/cm3
  • Boiling Point: 633.7ºC at 760 mmHg
  • Melting Point: 270-273 °C(lit.)
  • Flash Point: 337ºC

Caulophyllumine A

Caulophyllumine A is a natural product that can be isolated from blue cohosh[1].

  • CAS Number: 1009318-60-8
  • MF: C15H21NO4
  • MW: 279.332
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 451.8±40.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 227.0±27.3 °C

MCOPPB trihydrochloride

MCOPPB 3Hcl is a nociceptin receptor agonist with pKi of 10.07; weaker activity at other opioid receptors.IC50 value: 10.07 (pKi)Target: nociceptin receptorMCOPPB trihydrochloride is a trihydrochloride form of MCOPPB that is a new nonpeptide nociceptin/orphanin FQ peptide (NOP)-receptor agonist with a pKi of 10.07 ± 0.01 for the human NOP receptor.

  • CAS Number: 1108147-88-1
  • MF: C26H43Cl3N4
  • MW: 518.005
  • Catalog: Opioid Receptor
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sodium (2-2H1)acetate

Pivalate-d3 (sodium) is the deuterium labeled Sodium pivalate[1].

  • CAS Number: 39230-37-0
  • MF: C2H2DNaO2
  • MW: 83.040
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 117.1ºC at 760mmHg
  • Melting Point: >300ºC (dec.)(lit.)
  • Flash Point: 40ºC

Boc-N-methyl-L-leucine

Boc-N-Me-Leu-OH is a leucine derivative[1].

  • CAS Number: 53363-89-6
  • MF: C12H23NO4
  • MW: 245.315
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 338.2±21.0 °C at 760 mmHg
  • Melting Point: 55-60 ℃
  • Flash Point: 158.3±22.1 °C

Bad BH3 (mouse)

Bad BH3 (mouse) is a biological active peptide. (This is a bcl-2 binding peptide. This peptide is derived from the BH3 domain (a death domain) of Bad, amino acid residues 140 to 165.)

  • CAS Number: 505070-07-5
  • MF: C133H204N40O38S
  • MW: 3003.35
  • Catalog: Bcl-2 Family
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Tyrosylvaline

Tyrosylvaline is a biologically active peptide.

  • CAS Number: 17355-09-8
  • MF: C14H20N2O4
  • MW: 280.32000
  • Catalog: Others
  • Density: 1.245 g/cm3
  • Boiling Point: 572ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 299.7ºC

HC-056456

HC-056456 is an effective but not perfectly-selective blocker of CatSper channels. The [Na+]i rise is slowed by HC-056456 (IC50~3 µM).

  • CAS Number: 7733-96-2
  • MF: C12H6N2O4S2
  • MW: 306.31700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Caffeoyl-Coenzym A

Caffeoyl-CoAcould be isolated from leaf tissues of Gramineae with a Km value of 1.45 μM[1].

  • CAS Number: 53034-79-0
  • MF: C30H42N7O19P3S
  • MW: 929.67600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

4-Trifluoromethylsalicylic acid

4-Trifluoromethylsalicylic acid (Desacetyl triflusal) is a platelet aggregation inhibitor[1].

  • CAS Number: 328-90-5
  • MF: C8H5F3O3
  • MW: 206.119
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 286.4±40.0 °C at 760 mmHg
  • Melting Point: 178ºC
  • Flash Point: 127.0±27.3 °C

Monochlorobimane

Monochlorobimane is a fluorescent dye (λex=380 nm, λem=470 nm).

  • CAS Number: 76421-73-3
  • MF: C10H11ClN2O2
  • MW: 226.66000
  • Catalog: Dye Reagents
  • Density: 1.4g/cm3
  • Boiling Point: 314.9ºC at 760 mmHg
  • Melting Point: 135-136ºC(lit.)
  • Flash Point: 144.2ºC

Cistanoside F

Cistanoside F is a phenylethanoid glycosid isolated from Cistanche deserticola, with antioxidative effect[1].

  • CAS Number: 97411-47-7
  • MF: C21H28O13
  • MW: 488.439
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 880.7±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 302.8±27.8 °C

2''-O-Rhamnosylicariside II

2''-O-Rhamnosylicariside II is a flavonoid glycoside compound and might be beneficial for improving postmenopausal osteoporosis.

  • CAS Number: 135293-13-9
  • MF: C33H40O14
  • MW: 660.662
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 892.8±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 283.2±27.8 °C

Precyasterone

Precyasterone is a natural product isolated from the dried roots of Cyathula capitata[1].

  • CAS Number: 27335-85-9
  • MF: C29H44O8
  • MW: 520.655
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 726.3±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 235.9±26.4 °C

Methyl 4-hydroxy-3,5-dimethoxybenzoate

Methyl syringate, a chemical marker of asphodel monofloral honey, is an efficient phenolic mediator for bacterial and fungal laccases. Methyl syringate is a TRPA1 agonist[1][2][3].

  • CAS Number: 884-35-5
  • MF: C10H12O5
  • MW: 212.199
  • Catalog: TRP Channel
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 339.9±37.0 °C at 760 mmHg
  • Melting Point: 103-107 °C
  • Flash Point: 132.4±20.0 °C

L-beta-Homoglutamic acid hydrochloride

H-β-HoGlu-OH.HCl is a glutamic acid derivative[1].

  • CAS Number: 61884-74-0
  • MF: C6H12ClNO4
  • MW: 197.61700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 375.5ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 180.9ºC

RFARKGALRQKNVHEVKN

Protein Kinase C (19-36) is a pseudosubstrate peptide inhibitor of protein kinase C (PKC), with an IC50 of 0.18 μM. Protein Kinase C (19-36) markedly attenuated vascular hyperproliferation and hypertrophy as well as glucose-induced suppression of natriuretic peptide receptor response[1].

  • CAS Number: 113731-96-7
  • MF: C93H159N35O24
  • MW: 2151.48
  • Catalog: PKC
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Amino-2-deoxy-D-galactose-15N hydrochloride

Amino-2-deoxy-D-galactose-15N hydrochloride is the 15N labeled Amino-2-deoxy-D-galactose hydrochloride[1].

  • CAS Number: 478518-55-7
  • MF: C6H14ClNO5
  • MW: 216.62500
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-(Cyclohexylamino)-1-propanesulfonic Acid-d17

3-(Cyclohexylamino)-1-propanesulfonic Acid-d17 is the deuterium labeled CAPS[1]. CAPS, cyclohexylaminopropane sulfonic acid, is a surfactant. CAPS can be used as biological buffer (0.05 M, pH 11) for dialysis[2][3].

  • CAS Number: 1219804-15-5
  • MF: C9H2D17NO3S
  • MW: 238.422
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

WNK-IN-11

WNK-IN-11 is an allosteric With-No-Lysine (WNK) kinase inhibitor, with an IC50 of 4 nM for WNK1.

  • CAS Number: 2123489-30-3
  • MF: C21H21Cl2N5OS
  • MW: 462.4
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

6-Methylpurine-2’-deoxy-2’-fluoro-beta-D-arabinoriboside

6-Methylpurine-2’-deoxy-2’-fluoro-beta-D-arabinoriboside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

  • CAS Number: 2095417-72-2
  • MF:
  • MW:
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Dielaidoylphosphatidylethanolamine

Dielaidoylphosphatidylethanolamine is a liposome used to deliver drugs[1].

  • CAS Number: 16777-83-6
  • MF: C41H78NO8P
  • MW: 744.03400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Scopoline

Scopoline (compound 3a) is a compound easily formed from scopine[1].

  • CAS Number: 487-27-4
  • MF: C8H13NO2
  • MW: 155.19
  • Catalog: Others
  • Density: 1.284 g/cm3
  • Boiling Point: 248ºCat 760 mmHg
  • Melting Point: 107-109ºC
  • Flash Point: 111.6ºC