Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

H-Leu-Gly-OH

H-Leu-Gly-OH is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 686-50-0
  • MF: C8H16N2O3
  • MW: 188.22400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: -245ºC (dec.)
  • Flash Point: N/A

TRPM8 antagonist 3

TRPM8 antagonist 3 is a novel TRPM8 blocker with an IC50 value of 11 nM.

  • CAS Number: 2102179-29-1
  • MF: C13H12N2O4S
  • MW: 292.31
  • Catalog: TRP Channel
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

β-Fructosidase

β-Fructosidase is an enzyme that hydrolyzes sucrose to release fructose and glucose[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

AEBSF HCl

AEBSF is an irreversible inhibitor of serine proteases, such as chymotrypsin, kallikrein, plasmin, thrombin, and trypsin.

  • CAS Number: 30827-99-7
  • MF: C8H11ClFNO2S
  • MW: 239.695
  • Catalog: Thrombin
  • Density: N/A
  • Boiling Point: 292.5ºC at 760 mmHg
  • Melting Point: 175-177 °C
  • Flash Point: 130.7ºC

Lenacil

Lenacil is a selective uracil substituted herbicide used for control of both annual grasses, broad leafed weeds and some perennial weeds in sugarcane, apples, alfalfa, peaches, peacans, peppermints (Mentha piperita) and sugar beets. Lenacil can inhibit photosynthesis[1][2].

  • CAS Number: 2164-08-1
  • MF: C13H18N2O2
  • MW: 234.29400
  • Catalog: Others
  • Density: 1.32
  • Boiling Point: 411ºC at 760mmHg
  • Melting Point: 316-326°C
  • Flash Point: 202.4ºC

Tropolone

Tropolone, a  tropone derivative with a hydroxyl group in the 2-position, is a precursor of manyazulene derivatives such as methyl 2-methylazulene-1-carboxylate[1]. Tropolone is a potent inhibitor of mushroom tyrosinase with a IC50 of 0.4 μM, and the inhibition can be reversed by dialysis or by excess CU2+[2].

  • CAS Number: 533-75-5
  • MF: C7H6O2
  • MW: 122.121
  • Catalog: Tyrosinase
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 290.1±33.0 °C at 760 mmHg
  • Melting Point: 50-52 °C(lit.)
  • Flash Point: 122.0±18.0 °C

H-Pro-Gly-Pro-OH

H-Pro-Gly-Pro-OH is a collagen-derived matrikine that has classically been described as a neutrophil chemoattractant. H-Pro-Gly-Pro-OH is perfectly positioned to focus neutrophils on the site required and direct a localized repair response. H-Pro-Gly-Pro-OH activates the transcription of neurotrophins and their receptor genes after cerebral ischemia[1][2].

  • CAS Number: 7561-51-5
  • MF: C12H19N3O4
  • MW: 269.29700
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

VIHS

VIHS is a 4 amino acid peptide.

  • CAS Number: 309247-91-4
  • MF: C20H34N6O6
  • MW: 454.52
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

ETHYL 3,5-DIHYDROXYBENZOATE

Ethyl 3,5-dihydroxybenzoate is an active compound. Ethyl 3,5-dihydroxybenzoate can be used for the research of various biochemical studies[1].

  • CAS Number: 4142-98-7
  • MF: C9H10O4
  • MW: 182.173
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 356.2±12.0 °C at 760 mmHg
  • Melting Point: 127-130ºC(lit.)
  • Flash Point: 146.1±13.1 °C

6-Hydroxy-7-(isopentenyloxy)-2H-1-benzopyran-2-one

Prenyletin is a natural product, that can be isolated from the roots of Ptaeroxylon obliquum Radlk. (Rutaceae). Prenyletin shows anti-oxidative stress activity[1].

  • CAS Number: 15870-91-4
  • MF: C14H14O4
  • MW: 246.26
  • Catalog: Others
  • Density: 1.237g/cm3
  • Boiling Point: 451.6ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 173.9ºC

3,6,9,12-Tetraoxatetracosan-1-ol

PEG 4 lauryl ether can be used as an excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1].

  • CAS Number: 5274-68-0
  • MF: C20H42O5
  • MW: 362.54
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 450.3±30.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 226.1±24.6 °C

Homopropargylglycine

Homopropargylglycine is a Methionine (HY-13694) analogue. Homopropargylglycine is incorporated at a suitable rate into newly synthesized proteins in a variety of systems, including mammalian cell culture. Homopropargylglycine can be used to identify old and new protein populations[1].

  • CAS Number: 215160-72-8
  • MF: C6H9NO2
  • MW: 127.14100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Disperse Blue 60

Disperse Blue 60 is a textile anthraquinone dye[1].

  • CAS Number: 12217-80-0
  • MF: C20H17N3O5
  • MW: 379.36600
  • Catalog: Others
  • Density: 1.495 g/cm3
  • Boiling Point: 677.5ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 363.5ºC

BI-3406

SOS1-IN-2 is a Son of Sevenless 1 (SOS1) inhibitor extracted from patent WO2018115380A1, compound I-6, and it has an IC50 of 6 nM[1].

  • CAS Number: 2230836-55-0
  • MF: C23H25F3N4O3
  • MW: 462.46
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

methyl 1-acetyloxy-2,2,5,5-tetramethylpyrrolidine-3-carboxylate

AMCPy is a potent electron paramagnetic resonance (EPR) brain imaging agent, possessing excellent lipophilicity for blood−brain barrier (BBB) penetration[1].

  • CAS Number: 439858-38-5
  • MF: C12H21NO4
  • MW: 243.29900
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-Glu(AMC)-OH

H-Glu(AMC)-OH is aamino acid derivatives.

  • CAS Number: 72669-53-5
  • MF: C15H16N2O5
  • MW: 304.30
  • Catalog: Others
  • Density: 1.406 g/cm3
  • Boiling Point: 698ºC at 760 mmHg
  • Melting Point: 212 - 215ºC
  • Flash Point: 375.9ºC

epsilon-polylysine

Epsilon-polylysine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 28211-04-3
  • MF: C6H12N2O
  • MW: 128.17200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

1-Phenyl-2-nitro-1-propene

Wright's stain is a hematologic stain that facilitates the differentiation of blood cell types. Wright's stain is classically a mixture of eosin (red) and methylene blue dyes. It is used primarily to stain peripheral blood smears, urine samples, and bone marrow aspirates. Wright's stain provides a manual or automated stain for bone marrow and peripheral blood smears[1].

  • CAS Number: 68988-92-1
  • MF: C36H27Br4N3O5S++
  • MW: 163.173
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 263.0±9.0 °C at 760 mmHg
  • Melting Point: -98ºC
  • Flash Point: 115.7±11.5 °C

Gly6 hydrochloride

Gly6 hydrochloride (Hexaglycine hydrochloride) is a linear glycine oligopeptide with six glycines[1][2].

  • CAS Number: 71176-49-3
  • MF: C12H21ClN6O7
  • MW: 396.78
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N3-Aca-Aca-OH

N3-Aca-Aca-OH is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1].

  • CAS Number: 866363-71-5
  • MF: C12H22N4O3
  • MW: 270.33
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

N-Acetyl-DL-aspartic acid

2-Acetamidosuccinic acid is an aspartic acid derivative[1].

  • CAS Number: 2545-40-6
  • MF: C6H9NO5
  • MW: 175.139
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 425.3±35.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 211.0±25.9 °C

Ladanetin-6-O-β-(6′′-O-acetyl)glucoside

Ladanetin-6-O-β-(6′′-O-acetyl)glucoside is a flavonoid isolated from the whole plants of Dracocephalum tanguticum, with antioxidant ability. Flavonoids from Dracocephalum tanguticum show cardioprotective effects against Doxorubicin (HY-15142A)-induced toxicity in H9c2 cells[1].

  • CAS Number: 1256959-27-9
  • MF: C24H24O12
  • MW: 504.44
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

SNPB

SNPB is a cleavable linker that is used for making antibody-drug conjugate (ADC).

  • CAS Number: 663598-85-4
  • MF: C13H13N3O6S2
  • MW: 371.39
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Peginterferon lambda-1a

Peginterferon lambda-1a (BMS-914143) is a monoclonal antibody targeting IFNLR1 and consists of IFNL1 conjugated to pegol[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

δ-amyrin

δ-Amyrin is a compound isolated from the bark of Scaevola floribunda[1].

  • CAS Number: 508-04-3
  • MF: C30H50O
  • MW: 426.72
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 491.2±44.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 217.8±20.7 °C

HG-7-85-01-NH2

HG-7-85-01-NH2 is the ligand of SNIPER(ABL)-033. SNIPER(ABL)-033, conjugating HG-7-85-01 (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 value of 0.3 μM[1].

  • CAS Number: 1258391-29-5
  • MF: C27H27F3N6OS
  • MW: 540.60
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

7'-O-DMT-morpholino thymine

7'-O-DMT-morpholino thymine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

  • CAS Number: 143485-05-6
  • MF: C31H33N3O6
  • MW: 543.61
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

PMSF

PMSF is an irreversible serine/cysteine protease inhibitor commonly used in the preparation of cell lysates.

  • CAS Number: 329-98-6
  • MF: C7H7FO2S
  • MW: 174.193
  • Catalog: Cathepsin
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 285.7±19.0 °C at 760 mmHg
  • Melting Point: 92-95 °C
  • Flash Point: 126.6±21.5 °C

Paullinic acid

Paullinic acid is a long-chain fatty acid that has been detected in multiple biofluids, such as blood and urine.

  • CAS Number: 17735-94-3
  • MF: C20H38O2
  • MW: 310.51500
  • Catalog: Others
  • Density: 0.895g/cm3
  • Boiling Point: 426.3ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 323ºC

alpha-D-glucose-13C6

alpha-D-glucose-13C6 is 13C-labeled alpha-D-glucose (HY-128417). alpha-D-glucose is an endogenous metabolite.

  • CAS Number: 40010-60-4
  • MF: 13C6H12O6
  • MW: 186.11
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A