Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Oleic alcohol

Oleyl alcohol is an active compound. Oleyl alcohol can be used for various studies[1].

  • CAS Number: 143-28-2
  • MF: C18H36O
  • MW: 268.478
  • Catalog: Others
  • Density: 0.8±0.1 g/cm3
  • Boiling Point: 333.0±0.0 °C at 760 mmHg
  • Melting Point: 0-5.0 °C(lit.)
  • Flash Point: 120.7±15.6 °C

Polycarbophil

Polycarbophil can be used as an excipient, such as ointment base, release blocker, thickener, emulsifier. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1].

  • CAS Number: 9003-97-8
  • MF: C11H9N3O2.Na+
  • MW: 238.19786
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

6PPD-Q

6PPD-Q (6PPD-Quinone) is an endogenous metabolite that can be found in human urine and can also commonly found in the environment[1].

  • CAS Number: 2754428-18-5
  • MF: C18H22N2O2
  • MW: 298.38
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(4E)-1,7-Bis(4-hydroxyphenyl)-4-hepten-3-one

Platyphyllenone is a narutal product that can be isolated from Alnus japonica[1].

  • CAS Number: 56973-65-0
  • MF: C19H20O3
  • MW: 296.36
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 529.1±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 287.9±26.6 °C

2'-O-Methylphloretin (4,2',4'-Trihydroxy-6'-methoxydihydrochalcone)

2′-O-Methylphloretin (compound 3) is a flavonoid derivative. 2′-O-Methylphloretin can be isolated from the leaves of Melodorum siamensis. 2′-O-Methylphloretin inhibits the tumor cell line replication[1].

  • CAS Number: 111316-17-7
  • MF: C16H16O5
  • MW: 288.30
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Diosgenin-3-O-β-D-sodium glucuronide

Diosgenin-3-O-β-D-sodium glucuronide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 32471-99-1
  • MF: C33H49NaO9
  • MW: 612.33
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

DiIC1(5)

1,1',3,3,3',3'-Hexamethylindodicarbocyanine (iodide) is a carbocyanine dye that stains mitochondria of live cells.

  • CAS Number: 36536-22-8
  • MF: C27H31IN2
  • MW: 510.45
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 264ºC (dec.)(lit.)
  • Flash Point: N/A

Lin28-let-7a antagonist 1

Lin28-let-7a antagonist 1 shows a clear antagonistic effect against the Lin28-let-7a interaction with an IC50 of 4.03 μM for Lin28A-let-7a-1 interaction.

  • CAS Number: 2024548-03-4
  • MF: C31H29N5O7
  • MW: 583.59
  • Catalog: MicroRNA
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Santin

Santin is a flavonol isolated from Dodonaea uscosa[1].

  • CAS Number: 27782-63-4
  • MF: C18H16O7
  • MW: 344.32
  • Catalog: Others
  • Density: 1.45g/cm3
  • Boiling Point: 597ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 219.9ºC

1-Benzoylpiperazine-d8

1-Benzoylpiperazine-d8 is the deuterium labeled 1-Benzoylpiperazine[1].

  • CAS Number: 1219805-49-8
  • MF: C11H6D8N2O
  • MW: 198.291
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 341.3±35.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 160.2±25.9 °C

Lophanthoidin E

Lophanthoidin E is a diterpenoids compound isolated from the dried leaves of Rabdosia lophanthoides[1].

  • CAS Number: 120462-45-5
  • MF: C22H30O7
  • MW: 406.469
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 551.3±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 186.4±23.6 °C

Cd(II) protoporphyrin IX

Cd(II) protoporphyrin IX is a protoporphyrin IX. Protoporphyrin IX is a heterocyclic organic compound, which consists of four pyrrole rings, and is the final intermediate in the heme biosynthetic pathway[1].

  • CAS Number: 80216-25-7
  • MF: C34H32CdN4O4
  • MW: 673.05300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

3-TYP

3-TYP is a selective SIRT3 inhibitor, with an IC50 of 16 nM, more potent over SIRT1 (IC50=88 nM), SIRT2 (IC50=92 nM).

  • CAS Number: 120241-79-4
  • MF: C7H6N4
  • MW: 146.14900
  • Catalog: Sirtuin
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-Dap(Z)-OH

(S)-3-Benzyloxycarbonylamino-2-(Boc-amino)propionic acid is an alanine derivative[1].

  • CAS Number: 65710-57-8
  • MF: C16H22N2O6
  • MW: 338.356
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 546.2±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 284.1±30.1 °C

1-Propanamine, 3-azido-

3-Azidopropylamine is a click chemistry reagent containing an azide group. 3-Azidopropylamine can react with the starch sugar of potato starch for complexation and transfection of plasmid DNA[1].

  • CAS Number: 88192-19-2
  • MF: C3H8N4
  • MW: 100.12200
  • Catalog: Others
  • Density: 1.020 g/cm3
  • Boiling Point: 50 °C/15 mmHg
  • Melting Point: N/A
  • Flash Point: 60 °C

phenethyl alcohol xylopyranosyl-(1-6)-glucopyranoside

2-Phenethyl β-primeveroside is a phenplic that can be isolated from Callianthemum taipaicum[1].

  • CAS Number: 129932-48-5
  • MF: C19H28O10
  • MW: 416.42000
  • Catalog: Others
  • Density: 1.49g/cm3
  • Boiling Point: 661.3ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 353.7ºC

Quinacrine mustard dihydrochloride

Quinacrine mustard dihydrochloride is a fluorochrome. Quinacrine mustard dihydrochloride as a polycyclic aromatic agent can be used as mutagenic agent induces the mutants of bacteria. Quinacrine mustard dihydrochloride induces cell cycle arrest at G2/M-phase. Quinacrine mustard dihydrochloride has the potential for the research of plant, animal, or human chromosomes[1][2][3].

  • CAS Number: 4213-45-0
  • MF: C23H30Cl5N3O
  • MW: 541.76900
  • Catalog: Others
  • Density: 1.271g/cm3
  • Boiling Point: 574.1ºC at 760 mmHg
  • Melting Point: 150 °C
  • Flash Point: 301ºC

(3,4-Dimethoxyphenyl)(2H2)acetic acid

3,4-Dimethoxyphenylacetic acid-d2 is the deuterium labeled 3,4-Dimethoxyphenylacetic acid[1]. 3,4-Dimethoxyphenylacetic acid is a building block in the chemical synthesis[2].

  • CAS Number: 19031-58-4
  • MF: C10H10D2O4
  • MW: 198.212
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 331.4±27.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 130.2±17.2 °C

Senecionine acetate

Senecionine acetate (O-Acetylsenecionine) is a pyrrolizidine alkaloid. Senecionine acetate inhibits the sequestration of Ca2+ in extramitochondrial and mitochondrial compartments possibly by inactivating free sulfhydryl groups[1].

  • CAS Number: 126642-77-1
  • MF: C20H27NO6
  • MW: 377.43
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Bis(6-methylheptyl) Phthalate-3,4,5,6-d4

Bis(6-methylheptyl) Phthalate-3,4,5,6-d4 is the deuterium labeled Bis(6-methylheptyl) phthalate[1].

  • CAS Number: 2209087-06-7
  • MF: C24H34D4O4
  • MW: 394.58
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Neobavaisoflavone

Neobavaisoflavone, an isoflavone isolated from Psoralea corylifolia, has striking anti-inflammatory and anti-cancer effects. IC50 value: 42.93 μM (toward CCRF-CEM cells); 114.64 μM [against HCT116 (p53(+/+)) cells] [2]Target:In vitro: In the cancer cells, neobavaisoflavone sensitizes human U373MG glioma cells to TRAIL-mediated apoptosis; upregulated DR5 expression; induced TRAIL-mediated apoptosis in human glioma cells by suppressing migration and invasion, and by inhibiting anoikis resistance [1]. In caner cell lines, neobavaisoflavone is selectively active, and IC50 values below 115 μM were obtained on 6/9 cell lines, with values ranging from 42.93 μM (toward CCRF-CEM cells) to 114.64 μM [against HCT116 (p53(+/+)) cells] [2]. In vivo:

  • CAS Number: 41060-15-5
  • MF: C20H18O4
  • MW: 322.354
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 545.0±50.0 °C at 760 mmHg
  • Melting Point: 195-196ºC
  • Flash Point: 197.7±23.6 °C

hexatetracontane

Hexatetracontane is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 7098-24-0
  • MF: C46H94
  • MW: 647.23900
  • Catalog: Others
  • Density: 0.821 g/cm3
  • Boiling Point: 558.4ºC at 760mmHg
  • Melting Point: 86-89ºC
  • Flash Point: 468.1ºC

2-(2-[4-(1,1,3,3-Tetramethylbutyl)phenoxy]ethoxy)ethanol

Triton X-114 is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 9036-19-5
  • MF: (C2H4O)nC14H22O
  • MW: 294.429
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 402.6±35.0 °C at 760 mmHg
  • Melting Point: -5.99 °C
  • Flash Point: 197.3±25.9 °C

Liriodendrin

Liriodendrin is an HSF1 agonist can be isolated from E. ulmoides[1].

  • CAS Number: 573-44-4
  • MF: C34H46O18
  • MW: 742.72
  • Catalog: HSP
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 935.7±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 519.7±34.3 °C

Hoechst 33342

Hoechst 33342 is a DNA minor groove binder used fluorochrome for visualizing cellular DNA.

  • CAS Number: 23491-52-3
  • MF: C27H28N6O
  • MW: 452.55
  • Catalog: Dye Reagents
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 268ºC
  • Flash Point: N/A

6-Chlorovanillin

6-Chlorovanillin is identified in waste waters from bleached kraft pulp mills in Ontario and earlier also elsewhere>[1].

  • CAS Number: 18268-76-3
  • MF: C8H7ClO3
  • MW: 186.592
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 307.2±37.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 139.6±26.5 °C

volucrin

Volucrin is a dimeric phenanthrene derivative that can be isolated from the orchid lusia volucris[1].

  • CAS Number: 130217-31-1
  • MF: C32H26O8
  • MW: 538.54400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fmoc-Asp(OcHx)-OH

Fmoc-Asp(OcHex)-OH is an aspartic acid derivative[1].

  • CAS Number: 130304-80-2
  • MF: C25H27NO6
  • MW: 437.485
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 664.4±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 355.6±31.5 °C

3-hydroxy-2-(5-hydroxypentyl)chromen-4-one

3-Hydroxy-2-(5-hydroxypentyl)chromen-4-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 267400-83-9
  • MF: C14H16O4
  • MW: 248.27400
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2,6-Dimethoxybenzoic acid

2,6-Dimethoxybenzoic acid is a member of organic compounds known as o-methoxybenzoic acids and derivatives.

  • CAS Number: 1466-76-8
  • MF: C9H10O4
  • MW: 182.173
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 314.5±22.0 °C at 760 mmHg
  • Melting Point: 185187°C
  • Flash Point: 126.5±15.8 °C