Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

1-Heptanol-d1

1-Heptanol-d1 is the deuterium labeled 1-Heptanol[1].

  • CAS Number: 38007-42-0
  • MF: C7H15DO
  • MW: 117.207
  • Catalog: Others
  • Density: 0.8±0.1 g/cm3
  • Boiling Point: 176.9±3.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 73.9±0.0 °C

S-(LACTOYL)GLUTATHIONE

S-lactoylglutathione is a serum metabolite and can be used as a potential marker for sensitivity of gastric cancer to neoadjuvant chemotherapy[1].

  • CAS Number: 54398-03-7
  • MF: C13H19N3O8S
  • MW: 377.37
  • Catalog: Others
  • Density: 1.469g/cm3
  • Boiling Point: 772.1ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 420.8ºC

Trichlormethine (hydrochloride)

Trichlormethine hydrochloride is a cytostatic agent in the treatment of cancer and arthritis; shows carcinogenic effects to humans.

  • CAS Number: 817-09-4
  • MF: C6H13Cl4N
  • MW: 240.98600
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: 156.2ºC at 760 mmHg
  • Melting Point: 127-130ºC(lit.)
  • Flash Point: 48.3ºC

SBP-1

SBP-1 is a sulfite bioluminescent probe (SBP). SBP-1 exhibits the excellent responsivity, selectivity and sensitivity towards sulfite. The recognition of SBP-1 towards sulfite is based on the mechanism of a sulfite-mediated intramolecular cleavage reaction. SBP-1 can be used for detection of exogenous and endogenous sulfite in living animal. SBP-1 also possesses a capability for quantitatively detecting sulfite within a certain concentration range in solution[1].

  • CAS Number: 2451986-45-9
  • MF: C16H14N2O5S2
  • MW: 378.42
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Lupenone

Lupenone, isolated from Rhizoma Musae, belongs to lupane type triterpenoids. Lupenone shows various pharmacological activities including anti-inflammatory, anti-virus, anti-diabetes, anti-cancer, improving Chagas disease without major toxicity[1][2].

  • CAS Number: 1617-70-5
  • MF: C30H48O
  • MW: 424.702
  • Catalog: Cancer
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 487.9±12.0 °C at 760 mmHg
  • Melting Point: 165-167ºC
  • Flash Point: 278.4±5.7 °C

Tie2 kinase inhibitor

Tie2 kinase inhibitor 1 (compound 5) is a potent, selective Tie2 kinase inhibitor with an IC50 of 250 nM[1]. Tie2 kinase inhibitor 1 has anti-cancer activity[2].

  • CAS Number: 948557-43-5
  • MF: C26H21N3O2S
  • MW: 439.529
  • Catalog: Cancer
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 699.8±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 377.0±31.5 °C

(6α)-Hopane-6,22-diol

Zeorin is a compound isolated from the lichen Parmotrema sancti-angelii[1].

  • CAS Number: 22570-53-2
  • MF: C30H52O2
  • MW: 444.733
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 515.6±23.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 206.4±17.2 °C

ajugamarin F4

Ajugamarin F4 is a natural product. Ajugamarin F4 can be isolated from the leaves of Ajuga Parviflora[1].

  • CAS Number: 122587-84-2
  • MF: C29H42O9
  • MW: 534.63800
  • Catalog: Others
  • Density: 1.2g/cm3
  • Boiling Point: 622.5ºC at 760mmHg
  • Melting Point: 162-163 ºC
  • Flash Point: 260.5ºC

Boc-N'-(2-chloro-Cbz)-D-lysine

Boc-D-Lys(2-Cl-Z)-OH is a lysine derivative[1].

  • CAS Number: 57096-11-4
  • MF: C19H27ClN2O6
  • MW: 414.880
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 608.3±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 321.7±31.5 °C

Corylin

Corylin is a major bioactive compound isolated from Psoralea corylifolia L; antibiotic or anticancer compound.IC50 value:Target: in vitro: Corylin showed an inhibitory effect on IL-6-induced STAT3 promoter activity in Hep3B cells with IC50 value of 1.37 uM [1].

  • CAS Number: 53947-92-5
  • MF: C20H16O4
  • MW: 320.339
  • Catalog: Cancer
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 527.4±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 193.1±23.6 °C

CGP-53716

CGP 53716 is a potent protein tyrosine kinase inhibitor. CGP 53716 has selective activity of platelet-derived growth factor (PDGF) receptor. CGP 53716 can be used in the study of disease induced by abnormal cell proliferation induced by PDGF receptor activation [1].

  • CAS Number: 152459-94-4
  • MF: C23H19N5O
  • MW: 381.43
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Visnagin

Visnagin, an antioxidant furanocoumarin derivative, possess anti-inflammatory and analgesic properties. Visnagin has substantial potential to prevent Cerulein induced acute pancreatitis (AP). Visnagin possess promising vasodilator effects in vascular smooth muscles[1][2].

  • CAS Number: 82-57-5
  • MF: C13H10O4
  • MW: 230.216
  • Catalog: Cardiovascular Disease
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 378.2±42.0 °C at 760 mmHg
  • Melting Point: 139-142 °C
  • Flash Point: 182.5±27.9 °C

N-Methyl-L-leucine

(S)-4-Methyl-2-(methylamino)pentanoic acid is a leucine derivative[1].

  • CAS Number: 3060-46-6
  • MF: C7H15NO2
  • MW: 145.199
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 226.1±23.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 90.6±22.6 °C

Fibrinopeptide A, human TFA

Fibrinopeptide A, human TFA is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A, human locates at the NH2-termini of the Aα chain[1].

  • CAS Number: 61533-47-9
  • MF: C67H99F6N19O30
  • MW: 1764.62
  • Catalog: Cardiovascular Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

H-D-Phe(4-CN)-OH

H-D-Phe(4-CN)-OH is a phenylalanine derivative[1].

  • CAS Number: 263396-44-7
  • MF: C10H10N2O2
  • MW: 190.199
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 394.1±37.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 192.1±26.5 °C

Antennapedia Peptide

Antennapedia Peptide is a 16 amino acid peptide, originally derived from the 60 amino acid long homeodomain of the Drosophila transcription factor Antennapedia and is a member of the family of Cell-penetrating peptides.

  • CAS Number: 188842-14-0
  • MF: C104H168N34O20S
  • MW: 2246.728
  • Catalog: Peptides
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

HCH6-1

HCH6-1 is a competitive antagonist of Formyl peptide receptor 1 (FPR1), inhibits superoxide anion generation, elastase release, and chemotaxis in human neutrophils activated by fMLF (an FPR1 agonist). HCH6-1 can be used to treat neutrophilic inflammatory disease due to its inhibitory effects in neutrophil-like cells[1].

  • CAS Number: 1435265-06-7
  • MF: C28H27N3O4
  • MW: 469.53
  • Catalog: Inflammation/Immunology
  • Density: 1.259±0.06 g/cm3(Predicted)
  • Boiling Point: 790.8±60.0℃at 760 mmHg
  • Melting Point: N/A
  • Flash Point: N/A

Oxepan-2-one-d6

Oxepan-2-one-d6 is the deuterium labeled Oxepan-2-one[1].

  • CAS Number: 1219802-08-0
  • MF: C6H4D6O2
  • MW: 120.179
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 225.4±8.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 109.4±0.0 °C

Sodium (2H11)hexanoate

N-caproicacidsodiumsalt-d11 is the deuterium labeled N-caproicacidsodiumsalt[1].

  • CAS Number: 340257-58-1
  • MF: C6D11NaO2
  • MW: 149.208
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

TCTDSTNCYKAT

TCTDSTNCYKAT is an engineered-variant peptide of antifreeze protein (AFP)[1].

  • CAS Number: 1621188-94-0
  • MF: C51H82N14O22S2
  • MW: 1307.41
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

RGLS4326

RGLS4326 (RG4326) is a first-in-class, short oligonucleotide inhibitor of microRNA-17 (miR-17). RGLS4326 can be used for the research of autosomal dominant polycystic kidney disease (ADPKD). RGLS4326 inhibits miR-17 function in HeLa cells with an EC50 value of 28.3 nM[1].

  • CAS Number: 2229964-07-0
  • MF: C95H115F3N32O51P8S8
  • MW: 3082.42
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Anticonvulsant 7903

Lvguidingan is a potent anticonvulsant agent. Lvguidingan also has sedative-hypnotic, tranquilizing, and muscle-relaxing actions. Lvguidingan can be used as antiepileptic agent[1][2].

  • CAS Number: 82351-05-1
  • MF: C13H15Cl2NO
  • MW: 272.17
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Eperisone hydrochloride

Eperisone Hydrochloride ((±)-Eperisone hydrochloride) is an antispastic agent used for treatment of diseases characterized by muscle stiffness and pain. It works by relaxing both skeletal muscles and vascularsmooth muscles, thus demonstrating avariety of effects such as reduction ofmyotonia, improvement of circulationand suppression of the pain reflex. Eperisone Hydrochloride ((±)-Eperisone hydrochloride) is a centrally acting muscle relaxant inhibiting the pain reflex pathway, having a vasodilator effect[1][2 [3].

  • CAS Number: 56839-43-1
  • MF: C17H26ClNO
  • MW: 295.84700
  • Catalog: Neurological Disease
  • Density: 0.994g/cm3
  • Boiling Point: 386.8ºC at 760mmHg
  • Melting Point: 168-174ºC
  • Flash Point: 137.4ºC

L-Pyrrolysine lithium

L-Pyrrolysine lithium is the 22nd genetically encoded amino acid. L-Pyrrolysine lithium is an α-amino acid[1][2].

  • CAS Number: 852821-03-5
  • MF: C12H20LiN3O3
  • MW: 261.25
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

exo-Polygalacturonase

exo-Polygalacturonase is an extracellular pectinolytic enzyme. exo-Polygalacturonase acts from the non-reducing side, hydrolyzes pectic acids, and releases mono-galacturonate[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(6R,S)-5,10-Methenyl-5,6,7,8-tetrahydrofolic Acid

Anhydroleucovorin is a form of tetrahydrofolate and is a substrate for cyclohydrolase, which converts it to 10-formyltetrahydrofolate. Anhydroleucovorin can be used for research in the field of tumors[1][2].

  • CAS Number: 7444-29-3
  • MF: C20H21N7O6
  • MW: 455.42
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

17-Hydroxyjolkinolide A

17-Hydroxyjolkinolide A (Caudicifolin; Fischeriana A) is an insect feeding inhibitor isolated from the roots of spurge. 17-Hydroxyjolkinolide A induces grain aversion in S. zeamais and T. castaneum adults, with EC50s of 631.9 ppm and 656.5 ppm, respectively.

  • CAS Number: 65388-16-1
  • MF: C20H26O4
  • MW: 330.41800
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Clomazone

Clomazone is a broad spectrum herbicide used for control of annual grasses and broadleaf weeds in cotton, peas, pumpkins, soybeans, sweet potatoes, and tobacco[1].

  • CAS Number: 81777-89-1
  • MF: C12H14ClNO2
  • MW: 239.698
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 317.6±44.0 °C at 760 mmHg
  • Melting Point: 25°C
  • Flash Point: 145.9±28.4 °C

Sphingosylphosphorylcholine-d9

Sphingosylphosphorylcholine-d9 is deuterium labeled Sphingosylphosphorylcholine.

  • CAS Number: 2315262-28-1
  • MF: C23H40D9N2O5P
  • MW: 473.67
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Hythiemoside A

Hythiemoside A is found in Sigesbeckia orientalis L[1].

  • CAS Number: 853267-91-1
  • MF: C28H46O9
  • MW: 526.66
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 681.4±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 218.0±25.0 °C