Midecamycin, an acetoxy-substituted macrolide antibiotic, is tested against gram-positive and gram-negative bacteria.
L-Isoserine is a serine derivative[1].
Anticancer agent 149 (compound 3) is an anticancer agent isolated from the rhizome of Dioscorea dioscorea (DM). Anticancer agent 149 exhibits selective cytotoxic activity against MCF-7 cells (IC50=31.41 μM)[1].
H-Ser-His-OH is a short peptide with hydrolysis cleavage activity, an endogenous metabolite[1].
(Rac)-Mono(3,5,5-trimethylhexyl) phthalate is a important metabolite of commonly used phthalate plasticizers. (Rac)-Mono(3,5,5-trimethylhexyl) phthalate has immuno-suppressive effect[1].
Clothianidin-2-S-propanoic acid is a clothianidin hapten. Clothianidin-2-S-propanoic can be used for the research of insecticide[1].
5,5'-Dinitro BAPTA AM is a membrane-permeant, high-affinity calcium chelator, it can be used for investigation of the role of cytosolic Ca2+. 5,5'-Dinitro BAPTA AM can be loaded by incubation into live cells, and is cleaved by cytosolic esterases to liberate the active tetra-carboxylate ligand[1].
KRAS G12C inhibitor 25 is a KRAS G12C inhibitor. KRAS G12C inhibitor 25 inhibits SOSl-assisted GDP/GTP exchanging activity of KRAS-G12C mutant (IC50=0.48 nM). From WO2021216770A1 compound 3[1].
6''-O-trans-Feruloylcatalpol is a natural iridoid glycoside compound[1].
Tiamulin (Thiamutilin) is a diterpenic veterinary drug widely used in swine for the control of infectious diseases, including swine dysentery and enzootic pneumonia[1][2][3].
1,2,3,5-Tetramethylbenzene-d14 is the deuterium labeled 1,2,3,5-Tetramethylbenzene[1].
Montelukast sodium is a potent, selective CysLT1 receptor antagonist.
PXS-6302 hydrochloride is an irreversible lysyl oxidase inhibitor with IC50s of 3.7 μM (Bovine LOX), 3.4 μM (rh LOXL1), 0.4 μM (rh LOXL2), 1.5 μM (rh LOXL3), 0.3 μM (rh LOXL4), respectively. PXS-6302 hydrochloride has readily skin penetrability, reduces collagen deposition and significantly improves scar appearance[1].
9-Oxonerolidol is a farnesane-type sesquiterpenoid with anti-pathogens activity. 9-Oxonerolidol can be isolated from Chiliadenus lopadusanus. 9-Oxonerolidol acts as a post-infectional inhibitor from plants, and inhibits Gram+ and Gram? bacteria resistant to the antibiotic[1][2].
Aldose 1-epimerase (mutarotases) is a key enzyme of carbohydrate metabolism catalysing the interconversion of the α- and β-anomers of hexose sugars such as glucose and galactose. Aldose 1-epimerase is essential for normal carbohydrate metabolism and the production of complex oligosaccharides[1].
L-Arginine-13C6,15N4 ((S)-(+)-Arginine-13C6,15N4) hydrochloride is the 13C- and 15N-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
Lercanidipine-d3 hydrochloride is the deuterium labeled Lercanidipine. Lercanidipine is a lipophilic third-generation dihydropyridine-calcium channel blocker (DHP-CCB). Lercanidipine has long lasting antihypertensive action and reno-protective effect[1][2][3].
VPLSLYSG is an octapeptide that can be degraded by matrix metalloproteinase-9 (MMP-9), MMP-1 and MMP-2. VPLSLYSG has potential applications in MMP substrates[1][2][3].
Prohexadione (BX-112 free acid) is a plant growth regulator. Prohexadione inhibits gibberellin biosynthesis of plants[1][2].
Tetramethylammonium triacetoxyborohydride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Hydrazine-d6 (sulfate) is the deuterium labeled Hydrazine sulfate[1].
KW-8232, an orally active anti-osteoporotic agent, and can reduces the biosynthesis of PGE2[1].
Dehydroeburicoic acid monoacetate (Compound 18) is a lanostane triterpenoid isolated from Wolfiporia cocos[1].
FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 is a linker of AUTAC4. AUTAC4 contains an p-fluorobenzylguanine (FBnG) and a phenylindole moiety, which can induce K63-linked polyubiquitination and degradation of mitochondria in HeLa cells[1].
3-Hydroxybutyrate dehydrogenase (3-HBDH) is a mitochondrial enzyme, is often used in biochemical studies. 3-hydroxybutyrate dehydrogenase is involved in the synthesis and degradation of ketone bodies and butanoate metabolism. 3-Hydroxybutyrate dehydrogenase catalyzes (R)-3-hydroxybutanoate converts into acetoacetate[1].
Swietemahalactone is a natural compound isolated from Swietenia mahagoni. Swietemahalactone exhibits antibacterial activity aganist E. coli[1].
(±)-Vasicine is the racemate of Vasicine. Vasicine (Peganine), isolated from Peganum harmala seeds, significantly inhibits H+-K+-ATPase activity in vitro with an IC50 of 73.47 μg/mL. Anti-ulcer activity. Vasicine shows significant anti-secretory, antioxidant and cytoprotective effect[1].
ATTO 532 is a new type of fluorescent dye with high fluorescence yield, which can be used for most labeling applications, maximum excitation/emission wavelength: 532/552 nm.
Tetra-N-acetylchitotetraose elicits plant defense systems. Tetra-N-acetylchitotetraose is a component of the hpo-chitoo gosacchaπdes (LCOs) secreted from Rhizobia. Tetra-N-acetylchitotetraose is also a substrate for the Rhizobium leguminosarum nodulation protein NodB, a CO deacetylase[1].
PRMT5-IN-29 is a potent and orally active PRMT5 Inhibitor with an IC50 of 1.5 μΜ. PRMT5-IN-29 has the potential for advanced cancers research[1].