RO5256390 is an agonist of trace amine-associated receptor 1 (TAAR1), a highly conserved G-protein-coupled receptor (GPCR) bound by endogenous trace amines.RO5256390 can be used to reduce multiple behavioral effects of drugs of abuse through their actions on the mesocorticolimbic system[1].RO5256390 is a modulator of monoaminergic neurotransmission, blocks psychostimulant-induced hyperactivity and produces a brain activation pattern reminiscent of the antipsychotic drug olanzapine, suggesting antipsychotic-like properties[2].
Rebaudioside S is a minor steviol glycoside that can be isolated from the leaves of Stevia rebaudiana[1].
Brogidirsen exerts the stimulatory function of synthesis of functional dystrophin[1].
2,3-Diphosphoglyceric acid (2,3-DPG) pentasodium is an intermediate of the glycolytic pathway. 2,3-Diphosphoglyceric acid pentasodium stabilizes the deoxygenated form of hemoglobin by allosteric binding and facilitates oxygen release at tissue sites. 2,3-Diphosphoglyceric acid pentasodium binds to hemoglobin and decrease its affinity for oxygen[1][2].
(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoic acid is a glutamic acid derivative[1].
Simufilam (PTI-125) dihydrochloride is a low toxicity, orally active filamin A (FLNA) activator. Simufilam dihydrochloride preferentially binds altered FLNA and restores its native conformation, restores receptor and synaptic activities, reduces its a7nAChR/TLR4 associations and downstream pathologies. Simufilam dihydrochloride can be used for the research of Alzheimer's disease[1].
Fmoc-leucine-13C is a 13C-labeled Boc-Glycine[1].
Bifikafusp alfa (L19-IL2) is an immunotherapy fusion protein consisting of human L19 antibodies fused to the human cytokine interleukin 2 (IL2).Bifikafusp alfa is specific to the EDB domain of fibronectin. Bifikafusp alfa has anticancer activity[1].
(S)-3-((tert-Butoxycarbonyl)amino)-3-(3-(trifluoromethyl)phenyl)propanoic acid is a phenylalanine derivative[1].
Tyr-ACTH (4-9) is a behaviorally active peptide. Tyr-ACTH (4-9) can be used for research of learned behavior extinction in the rat[1].
20-Deoxocarnosol (compound 7) is a potent anti-cancer agent that can be found in the roots of Salvia deserta. 20-Deoxocarnosol shows cytotoxicity in cancer cells[1].
Mas7, a structural analogue of mastoparan, is an activator of heterotrimeric Gi proteins and its downstream effectors.
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-((tert-butoxycarbonyl)amino)phenyl)propanoic acid is a phenylalanine derivative[1].
YXG-158 (Compound 23-h) is an orally active AR degrader and CYP17A1 inhibitor. YXG-158 has AR degradation activity with DC50 value of 1.28 μM. YXG-158 can inhibit CYP17A1 with IC50 value of 100 nM. XG-158 can be used for the research of enzalutamide-resistant prostate cancer[1].
Methyl α-D-glucopyranoside-13C is the 13C labeled Methyl α-D-glucopyranoside[1].
Big Endothelin-2 (1-38), human is a polypeptide.
Ethyl 3-Bromopropionate-2,2,3,3-d4 is the deuterium labeled Ethyl 3-bromopropanoate[1].
Sulfo-cyanine3 azide sodium a water-soluble azide cyanine dye and fluorescent probe (Ex/Em=548/563 nm). Sulfo-cyanine3 azide sodium can be involved in synthesis of fused tricyclic heterocycles, produces immunostimulatory agents[1][2].
N-Boc-O-Benzyl-D-serine is a serine derivative[1].
Fmoc-Tyr(tBu)-Thr(psi(Me,Me)pro)-OH is a dipeptide.
4-Hydroxyantipyrine-d3 is the deuterium labeled 4-Hydroxyantipyrine.
Hydroxy-2-[2-(2-hydroxyphenyl)ethyl]chromone is a neuroprotective agent[1]. Hydroxy-2-[2-(2-hydroxyphenyl)ethyl]chromone shows significant neuroprotective activity against glutamate-induced neurotoxicity in primary cultures of rat cortical cell[1].
Trichloromethane is a solvent, as a chemical intermediate, and in pesticide formulations.
Biotin-Gastrin-1, human (1-17) is a biological active peptide. (Biotin-labeled HY-P1097)
(S)-4-Methoxydalbergione can be isolated from Dalbergia odorifera. (S)-4-Methoxydalbergione has anti-allergic and anti-inflammatory activity. (S)-4-Methoxydalbergione inhibits superoxide formation[1].
AZD5462 is a RXFP1 modulator, can be used for heart failure research. RXFP1 is the cognate receptor for human relaxin, belongs to GPCR family 1c number with anti-fibrotic and anti-inflammatory properties[1].
Isorauhimbine is an alkaloid, can be isolated from R. serpentina[1].
Liquiritigenin, a flavanone isolated from Glycyrrhiza uralensis, is a highly selective estrogen receptor β (ERβ) agonist with an EC50 of 36.5 nM for activation of the ERE tk-Luc.
O-Methyl-D-tyrosine is a tyrosine derivative[1].
L-Phenylalanylglycylglycine is a Glycine (HY-Y0966) derivative[1].