Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

H-Leu-Leu-Ala-OH

H-Leu-Leu-Ala-OH is a tripeptide composed of two L-leucine units joined to L-alanine by a peptide linkage. H-Leu-Leu-Ala-OH shows antioxidant activities[1].

  • CAS Number: 20274-80-0
  • MF: C15H29N3O4
  • MW: 315.41
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

α-lytic endopeptidase

From the myxobacterium Lysobacter enzymogenes. In peptidase family S1 (trypsin family) Reaction: Preferential cleavage: Ala┼, Val┼ in bacterial cell walls, elastin and other proteins

  • CAS Number: 37288-76-9
  • MF:
  • MW:
  • Catalog: Ser/Thr Protease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

AKOS B018304

AKOS B018304 is an arylalkylidene derivative, with polar substitution at para-position.

  • CAS Number: 6308-22-1
  • MF: C10H6N2O3S2
  • MW: 266.29600
  • Catalog: Others
  • Density: 1.6g/cm3
  • Boiling Point: 449.8ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 225.9ºC

Cyclopentadecanolide

ω-Pentadecalactone is a fragrance ingredient. ω-Pentadecalactone is a member of the fragrance structural group macrocyclic lactone and lactide derivative[1].

  • CAS Number: 106-02-5
  • MF: C15H28O2
  • MW: 240.382
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 344.8±10.0 °C at 760 mmHg
  • Melting Point: 34-38 °C(lit.)
  • Flash Point: 143.4±16.4 °C

3′-Acetate-ATP

3’-Acetate-ATP, an ATP analogue, is ATP acetylation product with an maxima uv absorption at 259 nm in water at neutral pH. 3’-Acetate-ATP exerts a blocking effect on nucleic acid polymerization[1].

  • CAS Number: 90290-58-7
  • MF: C12H18N5O14P3
  • MW: 549.22
  • Catalog: ATP Synthase
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(S)-N-Fmoc-2-(6'-heptenyl)alanine

(S)-N-FMoc-2-(6'-heptenyl)alanine is a amino acid, which can be used in peptide synthesis[1].

  • CAS Number: 1311933-83-1
  • MF: C25H29NO4
  • MW: 407.502
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 613.4±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 324.8±31.5 °C

Native Achromobacter lyticus Achromopeptidase

Lysyl endopeptidase (Lys-C) catalyzes carboxyl oxygen exchange reaction. Lysyl endopeptidase has higher substrate binding affinities and higher catalytic rates at the acidic pHs than at the alkaline pHs[1].

  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

CP671305

CP671305 is a potent, orally active, selective inhibitor of phosphodiesterase-4-D, and possesses high activities.

  • CAS Number: 445295-04-5
  • MF: C23H19FN2O7
  • MW: 454.405
  • Catalog: Phosphodiesterase (PDE)
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 664.1±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 355.4±31.5 °C

Ophiobolin B

Ophiobolin B, a sesterterpene metabolite of Helminthosporium oryzae, inhibits proton extrusion from maize coleoptiles. Ophiobolin B inhibits fusicoccin (FC) promoted proton extrusion, potassium uptake and cell enlargement[1]. The MIC values with the antifungal effect of Ophiobolins B on different zygomycetes is 25–50 μg/mL[2].

  • CAS Number: 5601-74-1
  • MF: C25H38O4
  • MW: 402.56700
  • Catalog: Fungal
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(+/-)-4-Hydroxy Mephenytoin

4-Hydroxymephenytoin is a metabolism of an antiepileptic drug mephenytoin, which is used as a CYP2C19 substrate.

  • CAS Number: 61837-65-8
  • MF: C12H14N2O3
  • MW: 234.251
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 153-154ºC
  • Flash Point: N/A

Amyloid β-Protein (4-42) ammonium salt

Amyloid β-Protein (4-42) is aAβ Fragment.

  • CAS Number: 157884-72-5
  • MF: C191H294N52O53S
  • MW:
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Zearalenone

Zearalenone is a mycotoxin produced mainly by fungi belonging to the genus Fusarium in foods and feeds. Possess oestrogenic activity in pigs, cattle and sheep, with low acute toxicity. Causes precocious development of mammae and other estrogenic effects in young gilts[1][2].

  • CAS Number: 17924-92-4
  • MF: C18H22O5
  • MW: 318.364
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 600.4±55.0 °C at 760 mmHg
  • Melting Point: 164-165°C
  • Flash Point: 219.5±25.0 °C

2,3-DIHYDROXY-4-METHOXYBENZOIC ACID

2,3-Dihydroxy-4-methoxybenzoic acid is a compound isolated from extracted from sweet cherry fruits (Prunus avium)[1].

  • CAS Number: 3934-81-4
  • MF: C8H8O5
  • MW: 184.15
  • Catalog: Others
  • Density: 1.499g/cm3
  • Boiling Point: 374.6ºC at 760mmHg
  • Melting Point: 207-208ºC
  • Flash Point: 157.2ºC

phenylethanolamine

2-Amino-1-phenylethanol is an analogue of noradrenaline.

  • CAS Number: 7568-93-6
  • MF: C8H11NO
  • MW: 137.179
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 286.9±13.0 °C at 760 mmHg
  • Melting Point: 56-58 °C(lit.)
  • Flash Point: 151.4±10.5 °C

Coronarin D

Coronarin D is a cytotoxic labdan-type diterpenes compound isolated from the rhizomes of H. coronarium[1].

  • CAS Number: 119188-37-3
  • MF: C20H30O3
  • MW: 318.450
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 466.7±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 186.9±21.5 °C

Isosaponarin

Isosaponarin is a flavone glycoside isolated from wasabi leaves. Isosaponarin increases collagen synthesis, caused by up-regulated TGF-β type II receptor (TβR-II) and prolyl 4-hydroxylase (P4H) proteins production[1].

  • CAS Number: 19416-87-6
  • MF: C27H30O15
  • MW: 594.518
  • Catalog: Others
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 970.8±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 322.4±27.8 °C

N-Methylcolchicine

Micromarin F (compound 9) is synthesized from osthole. Micromarin F against Balanus albicostatus and Bugula neritina with EC50 values of 10.93 and 12.38 μM[1].

  • CAS Number: 7336-40-5
  • MF: C23H27NO6
  • MW: 413.5
  • Catalog: Others
  • Density: 1.24g/cm3
  • Boiling Point: 683.2ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 367ºC

Guanosine 5'-triphosphate-5'-adenosine

Guanosine 5'-triphosphate-5'-adenosine, the 5′ cap analog, is a fluorescent substrate analog[1].

  • CAS Number: 10527-47-6
  • MF: C20H27N10O17P3
  • MW: 772.41
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

DDMAB

DDMAB is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 15163-30-1
  • MF: C18H37NO2
  • MW: 299.49200
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

boc-val-ome

(S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-methylbutanoate is a valine derivative[1].

  • CAS Number: 58561-04-9
  • MF: C11H21NO4
  • MW: 231.28900
  • Catalog: Others
  • Density: 1.02g/cm3
  • Boiling Point: 306ºC at 760mmHg
  • Melting Point: 194℃
  • Flash Point: 138.9ºC

Sodium 2-ethylhexyl sulfate

Sodium 2-ethylhexyl sulfate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 126-92-1
  • MF: C8H17NaO4S
  • MW: 232.273
  • Catalog: Others
  • Density: 1.12 g/mL at 20 °C(lit.)
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Lanolin

Lanolin is a yellow fat obtained from sheep's wool. Lanolin is used topically for sore, cracked nipples during breastfeeding[1].

  • CAS Number: 8006-54-0
  • MF: C54H84N16O21
  • MW: 104.10452
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 38-40 ºC
  • Flash Point: 209 ºC

Thioflavine T

Thioflavin T is a cationic Benzothiazole dye that shows enhanced fluorescence upon binding to amyloid in tissue sections.

  • CAS Number: 2390-54-7
  • MF: C17H19ClN2S
  • MW: 318.864
  • Catalog: Dye Reagents
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 212ºC
  • Flash Point: N/A

Valinomycin

Valinomycin (NSC 122023) is a cyclic depsipeptide antibiotic first isolated from Streptomyces fulvissimus, act as a potassium selective ionophore. Valinomycin (NSC 122023) inhibits lymphocyte proliferation by its effects on the cell membrane, and induces apoptosis in CHO cells[1].

  • CAS Number: 2001-95-8
  • MF: C54H90N6O18
  • MW: 1111.322
  • Catalog: Apoptosis
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 1333.9±65.0 °C at 760 mmHg
  • Melting Point: 186-190ºC
  • Flash Point: 760.5±34.3 °C

((4-(2-Chlorophenoxy)phenyl)sulfonyl)leucine

((4-(2-Chlorophenoxy)phenyl)sulfonyl)leucine is a leucine derivative[1].

  • CAS Number: 875901-35-2
  • MF: C18H20ClNO5S
  • MW: 397.87
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

5-Hydroxyferulic acid

5-Hydroxyferulic acid is a hydroxycinnamic acid and is a metabolite of the phenylpropanoid pathway. 5-Hydroxyferulic acid is a precursor in the biosynthesis of sinapic acid and is also a COMT non-esterifed substrate[1][2][3].

  • CAS Number: 1782-55-4
  • MF: C10H10O5
  • MW: 210.18300
  • Catalog: COMT
  • Density: 1.44g/cm3
  • Boiling Point: 449.1ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 182.8ºC

Taprenepag

CP-544326 is a potent and selective prostaglandin E2 receptor agonist with an EC50 of 2.8 nM.

  • CAS Number: 752187-80-7
  • MF: C24H22N4O5S
  • MW: 478.52000
  • Catalog: Prostaglandin Receptor
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sodium 2-oxobutanoate-13C4

Sodium 2-oxobutanoate-13C4 is the 13C labeled Sodium 2-oxobutanoate[1].

  • CAS Number: 2483736-24-7
  • MF: 13C4H5NaO3
  • MW: 128.04
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Octadecanedioic acid

Octadecanedioic acid, an endogenous metabolite, is a long-chain dicarboxylic acid that has been found in serum free fatty acid profile in Reye syndrome[1].

  • CAS Number: 871-70-5
  • MF: C18H34O4
  • MW: 314.460
  • Catalog: Others
  • Density: 1.0±0.1 g/cm3
  • Boiling Point: 480.9±18.0 °C at 760 mmHg
  • Melting Point: 125°C
  • Flash Point: 258.8±17.7 °C

4-[3-(Methylamino)-1-(2-thienyl)propyl]-1-naphthalenol

Para-Naphthol Duloxetine is a metabolite of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor (SNRI).

  • CAS Number: 949095-98-1
  • MF: C18H19NOS
  • MW: 297.415
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 497.2±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 254.5±28.7 °C