Cyclopropane-1-carboxylic Acid-d1 is the deuterium labeled Cyclopropane-1-carboxylic Acid[1].
PF-06424439 is an oral, potent and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14 nM[1]. PF-06424439 is slowly reversible, time-dependent inhibitor, which inhibits DGAT2 in a noncompetitive mode with respect to the acyl-CoA substrate[2].
Sulfo-NHS-Biotin (sodium) stongly label single SDS-2ME soluble cuticular protein[1].
Adamantane-carboxylic Acid-d15 is the deuterium labeled Adamantane-1-carboxylic acid[1].
6-Diazo-5-oxo-D-norleucine is a leucine derivative[1].
APB is a cell-permeable, efficient kinase cosubstrate with conversions and kinetics similar to those of other known ATP analogues. APB shows a cytotoxicity EC50 value of 19 ± 1 mM.APB is shown to promote biotin labeling of kinase substrates in live cells and has future applications in phosphoprotein purification and analysis. APB is cell-permeable and nontoxic at low mM concentrations, with cell penetration and labeling dependent on the polyamine linker.
H-Thr(tBu)-OH is a threonine derivative[1].
5,7-Dimethoxyflavanone is an active compound. 5,7-Dimethoxyflavanone can be Isolated from the roots of Zanthoxylum nitidum[1].
C13-112-tri-tail is a cationic lipid-like compound containing a polar amino alcohol head group, three hydrophobic carbon-13 tails, and a PEG2 linker. C13-112-tri-tail can be formulated into a lipid nanoparticle (LNP).
Adenosine 5'-diphosphate is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases.
Boc-L-Cys(Propargyl)-OH is a click chemistry reagent. Boc-L-Cys(Propargyl)-OH can be used for the research of various biochemical[1][2].
RB-OPD (NO-red) is a o-phenylenediamine (OPD)-locked rhodamine nitric oxide (NO) fluorescent probe with great sensitivity and selectivity (λex=550 nm, λem=590 nm)[1].
Lats-IN-1 is a potent and ATP-competitive inhibitor of Lats1 and Lats2 kinases. Lats-IN-1 promotes Yap-dependent proliferation in postmitotic mammalian tissues[1].
Dipotassium hydrogen phosphate is a highly water-soluble salt which is often used as a fertilizer, food additive and buffering agent. Dipotassium hydrogen phosphate can be used as an excipient, such as pH regulator, buffer. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].
Kemptide, 5-FAM labeled is a biological active peptide. (Kemptide is a phosphate acceptor peptide that serves as a synthetic substrate for PKA (Km = 16 μM). The corresponding fluorescent and biotinylated peptides are also proven to be good substrates for PKA. 5-FAM labeled HY-P0248)
Renin substrate, angiotensinogen (1-14), rat is a biological active peptide. (This peptide is derived from rat angiotensinogen amino acid residues 1-14. It is a synthetic renin substrate.)
Hypoxanthine-15N4 is the 15N labeled Hypoxanthine[1]. Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia[2].
3,5,6-Trichloro-2-pyridinol (TCP) is the main degradation product of the herbicide Triclopyr and the insecticides Chlorpyrifos and Chlorpyrifos-methyl[1].
Carboxypeptidase A (EC 3.4.2.1) is a zinc-containing metalloprotease, is often used in biochemical studies. Carboxypeptidase A catalyzes the hydrolysis of the peptide bonds that are adjacent to the C-terminal end of a polypeptide chain. Carboxypeptidase A is a prototypical enzyme for metalloproteases that plays important roles in biological systems[1].
HEPES sodium, a nonvolatile zwitterionic chemical buffering agent, is broadly applied in cell culture. HEPES sodium is effective at pH 6.8 to 8.2. HEPES sodium is also a potent inducer of lysosome biogenesis[1][2][3].
Calmodulin Binding Peptide 1 is a high affinity (pM) CaM-binding peptide derived from smooth muscle myosin light-chain kinase (MLCK peptide), which strongly inhibits IP3-induced Ca2+ release [1].
Ligupurpuroside C is a natural phenylethanoid glycoside isolated from Kudingcha[1].
4-Methoxyphenyl 2,6-Di-O-benzyl-β-D-galactopyranoside is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
TH10785 is a DNA glycosylase 1 (OGG1) activator, TH10785 can interact with the phenylalanine-319 and glycine-42 amino acids of OGG1 and increase the enzyme activity, generates β,δ-lyase enzymatic function. TH10785 can control the catalytic activity mediated by a nitrogen base within its molecular structure. TH10785 can be used for the research of various diseases and aging connected with DNA oxidative lesions[1].
(3,5-Diiodo-Tyr1,D-Ala2,N-Me-Phe4,glycinol5)-Enkephalin is a peptide.
Mono[2-(carboxymethyl)hexyl] phthalate-d4 is a deuterium labeled compound.
D-luciferin is the natural substrate of luciferases that catalyze the production of light in bioluminescent insects.
Pomalidomide-PEG1-NH2 hydrochloride is a crosslinker-E3 ligase ligand conjugate, consisting of an E3 ligase ligand pomalidomide and a PEGylated crosslinker with terminal amine for reactivity with a carboxyl group on the target ligand[1].
Fmoc-Asp-Ofm is an aspartic acid derivative[1].
Rhodamine 19 (perchlorate) is a metal free organic dye for dye sensitized solar cells.