(S)-BAY 73-6691 is the inactive isomer of BAY 73-6691 (HY-104028), and can be used as an experimental control. BAY 73-6691 ((R)-BAY 73-6691) is a potent, brain penetrant, and selective PDE9A inhibitor[1].
MAT2A-IN-5 is a potent inhibitor of MAT2A. The expression level of MAT2A is abnormally elevated in several types of tumors, including gastric, colon, liver and pancreatic cancers. MAT2A-IN-5 reduces the proliferative activity of MTAP-deficient cancer cells. MAT2A-IN-5 has the potential for the potential for the research of cancer diseases (extracted from patent WO2021254529A1, compound 1)[1].
Uperolein is a physalaemin-like endecapeptide, produced in the skin of Uperoleia rugosa and Uperoleia marmorata. Uperolein has a spasmodic effect on both the gastrointestinal tract and longitudinal muscles[1][2][3].
(R)-2,3-Dihydroxypropanal-3-13C is the 13C labeled (R)-2,3-Dihydroxypropanal[1].
Bexmarilimab (FP-1305) is a potent humanized anti-CLEVER-1 IgG4-antibody with an IC50 value of 4.51 nM. Bexmarilimab is capable of inducing a phenotypic M2 to M1 immune switch of tumor-associated macrophages. Bexmarilimab can be used in research of cancer[1].
(Cys47)-HIV-1 tat Protein (47-57) has membrane translocation function and can be used to derivatize the surface of magnetic pharmaceuticals and substantially facilitated their uptake into target cells[1][2].
Brevicornin is a flavonol from Epimedium brevicornum[1].
NSC 10281-d4 is the deuterium labeled NSC 10281[1].
Gondoic acid (cis-11-Eicosenoic acid), a monounsaturated long-chain fatty acid, is contained in a variety of plant oils and nuts[1].
4'-Methoxyflavonol is a synthesized flavone/flavonol with 1, 2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) bilayers[1].
F16 is a small molecule that selectively inhibits proliferation of mammary epithelial, neu-overexpressing cells, as well as a variety of mouse mammary tumor and human breast cancer cell lines. 1, F16 induced cell cycle arrest in sensitive mouse tumor and human cancer cell lines.2, Prolonged incubation with 3 uM F16 resulted in increased cell death of F16-sensitive cells but not of F16-resistant ones.3, F16 caused apoptosis in A6 cells.4, F16 caused a dramatic decrease in the number of cells in S phase and an increase in the percentage of cells in G1 phase.5, F16 is capable of inhibiting oxidative phosphorylation and inducing mitochondrial transmembrane depolarization.
4-Chlorobenzoic acid-d4 is the deuterium labeled 4-Chlorobenzoic acid-d4[1].
Z-LVG is an irreversible cysteine proteinase inhibitor. Z-LVG is a tripeptide derivative from cystatin C which can inhibit viral replication. Z-LVG can be used for virus diseases research[1].
Humantenidine, an indole alkaloid, is isolated from Gelsemium sempervirens.
Confusarin (compound 12) is a phenanthrene compound that was isolated from F. fimbriata for the first time[1].
Axomadol (EN3324) is a centrally active analgesic agent with opioid agonistic properties and inhibitory effects on the reuptake of monoamines[1].
Sialyl-Lewis X (sLeX) is a sialylated fucosylated tetrasaccharide, an endogenous antigen. Sialyl-Lewis X is a high-affinity ligand for selectins (E-, P-, and L-selectin)[1]. Sialyl-Lewis X binds to ELAM-1 and CD62 and has the ability to inhibits CD62-mediated neutrophil recruitment to sites of inflammation[2].
E260 is a Fer/FerT kinase inhibitor.
CGGRGD, a RGD derivative with cysteine as its N-terminal, CGGRGD is synthesized via solid-phase peptide synthesis technique and the surface of PCL fibers is aminolysised by amino 2-cyanobenzothiazole followed by the addition of 2-cyanobenzothiazole (CBT)[1].
FBPase-IN-2 (HS36) is a potent Fructose-1,6-bisphosphatase (FBPase) covalent inhibitor with an IC50 of 0.15 μM. FBPase-IN-2 reduces glucose production in hepatocytes. FBPase-IN-2 can be used for type 2 diabetes mellitus research[1].
17:0-14:1 PE-d5 is deuterium labeled 17:0-14:1 PE.
Corynantheine is a natural product that can be isolated from Pseudocinchona africana A. Chev.[1].
Schiarisanrin E (compound 5) is a lignan that can be isolated from Schisandra chinensis[1].
ent-16-Kaurene-3b,15b,18-triol is a ent-kaurene diterpene. ent-16-Kaurene-3b,15b,18-triol has significant antiallergic activity on β-hexosaminidase release induced by Polyginseng antigen[1].
MOC-Val-OH is a valine derivative[1].
N-(tert-Butoxycarbonyl)-N-cyclopropylglycine is a Glycine (HY-Y0966) derivative[1].
Fmoc-S-3-amino-4,4-diphenyl-butyric acid is an alanine derivative[1].
AIECbz-LD-C7 is an aggregation-induced emission (AIE) probe based on the conjugation of quinoline-malononitrile (QM) and carbazole. AIECbz-LD-C7 has excellent LD-specificity. AIECbz-LD-C7 can be used for tracking the dynamic changes of LDs and studying the association between LDs and lysosome/endoplasmic reticulum (ER)[1].
Xerophilusin G is a diterpenoid that can be isolated from Isodon enanderianus[1].
PNF21 is a new transdermal corticosteroid with anti-inflammatory activity.