5-[Boc(methyl)amino]pentanal is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Thalidomide-NH-CBP/p300 ligand 2 (P-007) is a PROTAC-based CBP and p300 degrader (extracted from patent WO2020173440)[1].
Benzyl-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Benzyl-PEG5-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Octaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTAC CDK9 degrader-4 is a highly potent and efficacious CDK9 degrader for targeting transcription regulation.
Azido-PEG9-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Mal-amido-PEG9-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
L-Azidohomoalanine-1,2,3,4-13C4 hydrochloride is the 13C- and 15N-labeled L-Azidohomoalanine hydrochloride. L-Azidohomoalanine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Bromo-PEG1-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Monoethyl pimelate is a PROTAC linker, which refers to the alkyl/ether composition. Monoethyl pimelate can be used in the synthesis of (S,R,S)-AHPC-Me-C7 ester, a specific BCL-XL PROTAC degrader[1].
Sulfo-NHS-Acetate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Boc-NH-PEG5-CH2CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC[1].
Bromo-PEG1-C2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
MS-PEG12-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTAC MDM2 Degrader-1 is a MDM2 degrader based on PROTAC technology. PROTAC MDM2 Degrader-1 composes of a potent MDM2 inhibitor, linker, and the MDM2 ligand for E3 ubiquitin ligase[1].
N-Boc-PEG-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Azide-PEG4-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Decaethylene glycol dodecyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
FAK PROTAC B5 (Compound B5) is a FAK PROTAC degrader with an IC50 value of 14.9 nM. FAK PROTAC B5 presents strong FAK degradation activity, antiproliferative activity, outstanding plasma stability and moderate membrane permeability. FAK PROTAC B5 inhibits cell migration and invasion[1].
dTAG-47, heterobifunctional dTAG molecule, targets mutant FKBP12 (FKBP12F36V). FKBP12F36V serves as a degradation tag (dTAG) and is fused to a protein of interest. dTAG-47 can be used for the research of basal-like breast cancers (BBC)[1].
m-PEG5-nitrile is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Boc-Aminooxy-PEG4-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
2-(Azido-PEG2-amido)-13-propandiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
t-Boc-Aminooxy-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Mal-amido-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Propargyl-PEG4-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
dBET1 is a potent BRD4 protein degrader based on PROTAC technology with an EC50 of 430 nM.
2-Phthalimidehydroxy-acetic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Boc-PEG4-methyl propionate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].