3′-Deoxy-3′-methylcytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
N2-Methylguanine is a modified nucleoside. N2-Methylguanine is an endogenous methylated nucleoside found in human fluids.
19(S)-Hydroxyconopharyngine (20-Hydroxyconopharyngine) is a natural product that can be isolated from Tabernaemontana bovina[1].
FAM hydrazide, 6-isomer is a hydrazide derivative of fluorescein (FAM). FAM is a xanthene dye, a parent of fluorescein dye series. FAM hydrazide, 6-isomer can be used for the labeling of carbonyl compounds, aldehydes, and ketones[1].
Permanent Orange is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Rubiarbonol B (Rubianol h) is an arborane type triterpenoid. Rubiarbonol B can be isolated from from the roots of Rubia cordifolia L[1].
3-O-(2'E,4'E-Decadienoyl)-ingenol is a natural diterpenoid that shows cytotoxicity against human normal cell lines L-O2 and GES-1, with IC50s of 8.22 μM and 6.67 μM, respectively[1].
(R)-Bromoenol lactone ((R)-BEL) is an irreversible, chiral, mechanism-based inhibitor of calcium-independent phospholipaseγ(iPLA2γ)(/b). (R)-BEL inhibits human recombinant iPLA2γ with an IC50 of approximately 0.6 µM[1].
H-Phg-OtBu.HCl is a Glycine (HY-Y0966) derivative[1].
DL-Glyceraldehyde-13C,d is the deuterium and 13C labeled DL-Glyceraldehyde[1].
7-Amino-3-chloro cephalosporanic acid (7-ACCA) is an important intermediate for the synthesis of the second generation cephalosporins Cefaclor (HY-B0198)[1].
(E/Z)-Methyl mycophenolate is a racemic compound of (Z)-Methyl mycophenolate and (E)-Methyl mycophenolate isomers. Methyl mycophenolate is a methyl ester of mycophenolic acid. Methyl mycophenolate can be used to synthesize mycophenolic acid β-D-glucuronide and phenolic glycosides[1][2].
4-Azido-D-phenylalanine, a derivative of phenylalanine, is a benchmark reagent, and can be used in the synthesis of compounds[1].
Broflanilide is a potential insecticide and metabolized to desmethyl-broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin (RDL) GABA receptor, and inhibits S. litura RDL GABAR, with an IC50 value of 1.3 nM.
D-Sorbitol-d2-2 is the deuterium labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and di
1,2-dioctanoyl-sn-glycero-3-phosphocholine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Orexin A (1-15) (free acid) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1].
DPP-IV-IN-5 is isolated from the fruits of Lycium barbarum. DPP-IV-IN-5 exerts moderate agonistic activities for peroxisome proliferator-activated receptor (PPARγ) with EC50 values of 10.09 - 44.26 μM and also presents inhibitory activity on dipeptidyl peptidase-4 (DPPIV) with an IC50 value of 47.13 μM [1].
Donidalorsen is an antisense oligonucleotide designed to reduce the production of prekallikrein (PKK). PKK plays an important role in the activation of inflammatory mediators associated with acute attacks of Hereditary angioedema (HAE).
HEPES, a zwitterionic chemical buffering agent, is broadly applied in cell culture. HEPES is effective at pH 6.8 to 8.2. HEPES is a potent inducer of lysosome biogenesis[1][2][3].
Queuine is a hypermodified nucleobase, which is modified to queuosine. Queuine, as an important micronutrient, can be used for the research of diseases associated with human gut microbiome[1].
Triptotriterpenic acid A is a natural product from Tripterygium wilfordii[1].
pGlu-Pro-Arg-MNA monoacetate is a chromogenic substrate.
N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine (5'-O-DMT-N4-Bz-dC) can be used for synthesis oligodeoxynucleotides containing a 3'-S-phosphorothiolate (3'-PS) linkage. N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine is an useful tool for probing enzyme-catalyzed cleavage processes in DNA[1].
(E)-2′,4′-Dimethoxychalcone is a flavonoid compound[1].
GL3, the major component of O. fragrans seeds, is a derivative based on both phenylethanoid and methyloleoside[1].
2,4-Difluorobenzaldehyde is an organic chemical, that can be used in medicine, pesticide, liquid crystal materials intermediate.
2-Hydroxy-1,3,4-trimethoxyanthraquinone is a anthraquinone that can be found in Cinchona ledgeriana[1].
Stilbostemin B is a stilbenoid compound that can be found in Stemona species[1].
GluR23Y is a biological active peptide. (This GluR23Y peptide was used in ELISA cell-surface assay for the insulin-stimulated endocytosis of native AMPA receptors in cultured hippocampal neurons. GluR23Y prevented any insulin-induced reduction. The blockade of insulin action was observed when the GluR23Y peptide was delivered into neurons by fusing it to the membrane transduction domain of HIV-1.)