Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

o-3M3FBS

o-3M3FBS is the negative control of m-3M3FBS. o-3M3FBS inhibits inward and outward currents via mechanisms independent of PLC acting in an antagonistic manner. In contrast, o-3M3FBS also causes an increase in [Ca2+]i in an agonistic manner[1].

  • CAS Number: 313981-55-4
  • MF: C16H16F3NO2S
  • MW: 343.36400
  • Catalog: Others
  • Density: 1.316g/cm3
  • Boiling Point: 424.3ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 210.4ºC

Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone

Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone is a cell-permeable, non-toxic inhibitor that binds irreversibly to activated caspase-3 in apoptotic cells. The fluorescence intensity can be measured by flow cytometry, microwell plate reader, or fluorescence microscopy[1].

  • CAS Number: 1926163-65-6
  • MF: C43H45FN4O16
  • MW: 892.83
  • Catalog: Caspase
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Tetramethylammonium acetate

Tetramethylammonium acetate hydrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 10581-12-1
  • MF: C6H15NO2
  • MW: 133.189
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 184 °C (dec.)(lit.)
  • Flash Point: N/A

5′-Des-O-methylharringtonine

5′-Des-O-methylharringtonine is a nature product that could be isolated from Cephalotaxus harringtonia[1].

  • CAS Number: 182325-73-1
  • MF: C27H35NO9
  • MW: 517.57
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Benzoyl-Phe-Ala-Arg

Benzoyl-Phe-Ala-Arg is a peptide.

  • CAS Number: 89020-38-2
  • MF: C25H32N6O5
  • MW: 496.56
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2,4(1H,3H)-Pyrimidinedione,1-(2-deoxy-b-D-threo-pentofuranosyl)-5-methyl

1-(2-Deoxy-β-D-threo-pentofuranosyl)thymine is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].

  • CAS Number: 16053-52-4
  • MF: C10H14N2O5
  • MW: 242.23
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: 1.452g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate

E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate is a synthesized compound that incorporates an E3 ligase ligand and a linker used in PROTAC technology.

  • CAS Number: 1950635-14-9
  • MF: C23H27F3N4O8
  • MW: 544.48
  • Catalog: E3 Ligase Ligand-Linker Conjugate
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

7-O-Methylbiochanin A

7-O-Methylbiochanin A (4',7-Dimethoxy-5-hydroxyisoflavone) is an isoflavone derivative isolated from the roots of Lotus polyphyllos[1].

  • CAS Number: 34086-51-6
  • MF: C17H14O5
  • MW: 298.29000
  • Catalog: Others
  • Density: 1.321 g/cm3
  • Boiling Point: 515.2ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: N/A

Z-Arg(Z)2-OH

Z-Arg(Z)2-OH is an arginine derivative[1].

  • CAS Number: 14611-34-8
  • MF: C30H32N4O8
  • MW: 576.597
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 137-140ºC
  • Flash Point: N/A

S-Benzyl-CD4 (83-94) peptide

[Cys(Bzl)84] CD (81-92) is an acidic peptide. [Cys(Bzl)84] CD (81-92) can be sequencing by negative ion postsource decay (PSD) spectra[1].

  • CAS Number: 123380-68-7
  • MF: C69H102N14O26S
  • MW: 1575.69000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Soyacerebroside I

Soyacerebroside I is a glycosphingolipid, together with Soyacerebroside II, which can be isolated from the seeds of Glycine max Merrill (Leguminosae). Soyacerebroside II shows ionophoretic activity for Ca2+[1].

  • CAS Number: 114297-20-0
  • MF: C40H75NO9
  • MW: 714.02
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 870.1±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 480.0±34.3 °C

Sodium methanesulfonate-d3

Sodium methanesulfonate-d3 is the deuterium labeled Sodium methanesulfonate[1].

  • CAS Number: 1610056-71-7
  • MF: CD3NaO3S
  • MW: 121.11
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

ARL 67156 trisodium salt

ARL67156 trisodium salt is an inhibitor of ecto-ATPase. ARL 67156 is a weak competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with Kis of 11, 18 and 12 μM, respectively[1].

  • CAS Number: 1021868-83-6
  • MF: C15H24Br2N5Na3O12P3
  • MW: 788.08
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Shinpterocarpin

Shinpterocarpin is a flavonoid that can be found in Glycyrrhiza glabra L.[1].

  • CAS Number: 157414-04-5
  • MF: C20H18O4
  • MW: 322.35
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

(+)-Isomenthone

(+)-Isomenthone is an isomenthone isolated from Ziziphora clinopodioides Lam.. (+)-Isomenthone is an isomer of L-Menthone[1][2].

  • CAS Number: 1196-31-2
  • MF: C10H18O
  • MW: 154.24900
  • Catalog: Others
  • Density: 0.881±0.06 g/cm3
  • Boiling Point: 204 °C
  • Melting Point: N/A
  • Flash Point: N/A

Ac-Gly-OEt

Ethyl acetylglycinate is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 1906-82-7
  • MF: C6H11NO3
  • MW: 145.156
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 262.8±0.0 °C at 760 mmHg
  • Melting Point: 43-46 °C(lit.)
  • Flash Point: 110.9±19.8 °C

Dimethicone

Dimethicone is an orally active biochemical assay reagents consisting of a fully methylated linear siloxane polymer whose ends are blocked by trimethylsiloxane units. Dimethicone can lubricate hair and physically block the respiratory system of lice to remove lice. Dimethicone has potential applications in cosmetics and daily cleaning products[1][2][3].

  • CAS Number: 9006-65-9
  • MF: C6H18OSi2
  • MW: 162.37800
  • Catalog: Others
  • Density: 1 g/mL at 20 °C
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: 121 °C

DCIP hydrate sodium

DCIP hydrate sodium is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

  • CAS Number: 283164-79-4
  • MF: C12H8Cl2NNaO3
  • MW: 308.09
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-Methylglutaric acid

2-Methylpentanedioic acid is a metabolite of succinic acid, a citric acid cycle intermediate.

  • CAS Number: 617-62-9
  • MF: C6H10O4
  • MW: 146.14100
  • Catalog: mGluR
  • Density: 1.246
  • Boiling Point: 214-215ºC22 mm Hg(lit.)
  • Melting Point: 82.5-84.5 ºC
  • Flash Point: 149ºC

Choline chloride

Choline chloride is an organic compound and a quaternary ammonium salt, an acyl group acceptor and choline acetyltransferase substrate, also is an important additive in feed especially for chickens where it accelerates growth.

  • CAS Number: 67-48-1
  • MF: C5H14ClNO
  • MW: 139.624
  • Catalog: Others
  • Density: 1.205 g/cm3
  • Boiling Point: N/A
  • Melting Point: 302-305 °C (dec.)(lit.)
  • Flash Point: N/A

(4S)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-1-methyl-D-proline

(4S)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-1-methyl-D-proline is a proline derivative[1].

  • CAS Number: 489447-09-8
  • MF: C11H20N2O4
  • MW: 244.2875
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 388.9±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 189.0±27.9 °C

Ammonium-15N,d4 chloride

Ammonium-15N,d4 (chloride) is the deuterium and 15N labeled Ammonium chloride[1].

  • CAS Number: 99011-95-7
  • MF: ClD4N
  • MW: 57.51610
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 340ºC (subl.)(lit.)
  • Flash Point: N/A

2-amino-9-(β-D-ribofuranosyl)purine

(2R,3R,4S,5R)-2-(2-amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (9-pentofuranosyl-9H-purin-2-amine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

  • CAS Number: 4546-54-7
  • MF: C10H13N5O4
  • MW: 267.24
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: 2.1±0.1 g/cm3
  • Boiling Point: 711.8±70.0 °C at 760 mmHg
  • Melting Point: 105-115ºC
  • Flash Point: 384.3±35.7 °C

MEXENONE

Mexenone is a benzophenone-derived sunscreening agent.

  • CAS Number: 1641-17-4
  • MF: C15H14O3
  • MW: 242.270
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 400.1±35.0 °C at 760 mmHg
  • Melting Point: 99-102°C
  • Flash Point: 150.2±19.4 °C

D-Val-Leu-Arg p-nitroanilide diacetate salt

D-Val-Leu-Arg-pNA is a glandular kininoreleasing enzyme substrate that also acts as a substrate for tissue-type plasminogen activator (t-PA) with no apparent affinity for fibrin[1].

  • CAS Number: 64816-14-4
  • MF: C23H38N8O5
  • MW: 506.59800
  • Catalog: Others
  • Density: 1.34g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

6-NBDG

6-NBDG is a fluorescent glucose analogue, it can be used for fluorescence imaging and monitoring glucose transport and uptake. 6-NBDG can be used as a fluorescent probe for detecting macrophage-rich atherosclerotic plaques[1][2].

  • CAS Number: 108708-22-1
  • MF: C12H14N4O8
  • MW: 342.262
  • Catalog: Others
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: 729.5±70.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 395.0±35.7 °C

Neuropeptide Y-Lys(biotinyl) (free acid) (human, rat) trifluoroacetate salt

Neuropeptide Y-Lys(biotinyl) (free acid) (human, rat) is a biologically active peptide.

  • CAS Number: 1927927-12-5
  • MF: C205H310N58O61S2
  • MW: 4627.14
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-Benzal-4-hydroxyacetophenone

4'-Hydroxychalcone, a chalcone isolated from licorice root, with hepatoprotective activity. 4'-Hydroxychalcone inhibits TNFα-induced NF-κB activation via proteasome inhibition. 4'-Hydroxychalcone induces a rapid potassium release from mitochondrial vesicles and causes deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria[1][2][3].

  • CAS Number: 2657-25-2
  • MF: C15H12O2
  • MW: 224.25500
  • Catalog: Others
  • Density: 1.191 g/cm3
  • Boiling Point: 419.6ºC at 760 mmHg
  • Melting Point: 174-178 °C
  • Flash Point: 179.1ºC

2'-Fluoro-5-methylarabinosyluracil

FMAU is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].

  • CAS Number: 69256-17-3
  • MF: C10H13FN2O5
  • MW: 260.22
  • Catalog: Nucleoside Antimetabolite/Analog
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

mnp-gal

MNP-GAL is MNPs coated with galactose. MNP-Gal can be used as substrate for the assay of NAG and beta-d-galactosidase[1][2].

  • CAS Number: 70622-78-5
  • MF: C15H19NO9
  • MW: 357.31300
  • Catalog: Others
  • Density: 1.502g/cm3
  • Boiling Point: 622.2ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 330.1ºC