Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Captopril EP Impurity D

Captopril EP Impurity D is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM)[1][2][3].

  • CAS Number: 56970-78-6
  • MF: C4H7BrO2
  • MW: 167.00100
  • Catalog: Others
  • Density: 1.625g/cm3
  • Boiling Point: 230.5ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 93.2ºC

Gyrophoric acid

Gyrophoric acid is a good ultraviolet filter in lichen populations. Gyrophoric acid shows DPPH radical scavenging activity with an IC50 value of 105.75 µg/ml[1][2].

  • CAS Number: 548-89-0
  • MF: C24H20O10
  • MW: 468.410
  • Catalog: Cancer
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 693.9±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 238.5±25.0 °C

1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d74

1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d74 is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-gly

  • CAS Number: 326495-38-9
  • MF: C44H14D74NO8P
  • MW: 864.60
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Galgravin

Galgravin is an active compound in Nectandra megapotamica, with anti-inflammatory activity. Galgravin displays in vitro cytotoxic activity and induce apoptosis in leukemia cells[1][2].

  • CAS Number: 528-63-2
  • MF: C22H28O5
  • MW: 372.45500
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Z-Gly-OSu

Z-Gly-Osu is a Glycine (HY-Y0966) derivative[1].

  • CAS Number: 2899-60-7
  • MF: C14H14N2O6
  • MW: 306.271
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 111-115ºC
  • Flash Point: N/A

(Rac)-Paclobutrazol-15N3

Rac-Paclobutrazol-15N3 is the 15N-labeled Rac-Paclobutrazol[1].

  • CAS Number: 2642083-16-5
  • MF: C15H20Cl15N3O
  • MW: 296.77
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Boc-Glu-Lys-Lys-AMC acetate salt

Boc-Glu-Lys-Lys-AMC is a sensitive fluorogenic substrate for urokinase-activated plasmin[1].

  • CAS Number: 73554-85-5
  • MF: C34H52N6O11
  • MW: 720.81000
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Bromobimane

Bromobimane is essentially nonfluorescent and converts into fluorescent products when reacts with small thiols.

  • CAS Number: 71418-44-5
  • MF: C10H11BrN2O2
  • MW: 271.11100
  • Catalog: Dye Reagents
  • Density: 1.66g/cm3
  • Boiling Point: 327.8ºC at 760 mmHg
  • Melting Point: 152-154ºC
  • Flash Point: 152.1ºC

Alisol A 24-acetate

Alisol A 24-acetate is a natural product.

  • CAS Number: 18674-16-3
  • MF: C32H52O6
  • MW: 532.752
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 641.1±55.0 °C at 760 mmHg
  • Melting Point: 194-196 ºC
  • Flash Point: 196.5±25.0 °C

15:0 Lyso PE-d5

15:0 Lyso PE-d5 is deuterium labeled 15:0 Lyso PE.

  • CAS Number: 2342574-96-1
  • MF: C20H37D5NO7P
  • MW: 444.55
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Acenaphthylene

Acenaphthylene is a polycyclic aromatic hydrocarbon (PAH). PAHs are derived naturally from coal and tar deposits, and produced by incomplete combustion of organic matter[1].

  • CAS Number: 208-96-8
  • MF: C12H8
  • MW: 152.192
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 298.9±7.0 °C at 760 mmHg
  • Melting Point: 78-82 °C(lit.)
  • Flash Point: 137.2±8.9 °C

Sodium tauroglycocholate

Sodium tauroglycocholate is an inhibitor of the biliary acid transporting system of the hepatocyte and also a surfactant used as a chemical permeation enhancer.

  • CAS Number: 41945-48-6
  • MF: C28H47N2NaO8S
  • MW: 594.736
  • Catalog: Endocrinology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

F(N-Me)GA(N-Me)IL

F(N-Me)GA(N-Me)IL is a biological active peptide. (Double N-methylated derivatives of amyloidogenic and cytotoxic partial IAPP sequence were found to be devoid of β-sheet structure, amyloidogenicity and cytotoxicity, The derivatives were able to interact with the native sequences and inhibit amyloid formation)

  • CAS Number: 409085-40-1
  • MF: C28H45N5O6
  • MW: 547.69
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Methylophiopogonone B

Methylophiopogonone B, a homoisoflavonoidal compound that could be isolated from Ophiopogonis Tiber, could scavenge •OH and H2O2 in vitro to a certain extent[1][2].

  • CAS Number: 74805-89-3
  • MF: C19H18O5
  • MW: 326.343
  • Catalog: Metabolic Disease
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 547.7±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 199.7±23.6 °C

NSC16168

NSC16168 is a specific inhibitor of ERCC1-XPF, with an IC50 value of 0.42 μM. NSC16168 inhibits DNA repair and potentiates CDDP efficacy in cancer[1].

  • CAS Number: 6837-93-0
  • MF: C17H15NO9S3
  • MW: 473.49700
  • Catalog: Cancer
  • Density: 1.683g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ethyl coumarin-3-carbaoxylate

Ethyl 3-coumarincarboxylate is a coumarin derivative. Ethyl 3-coumarincarboxylate can be used as a pseudo-template to give a molecularly imprinted polymer (MIP) that has a fairly specific recognition capability for aflatoxins[1].

  • CAS Number: 1846-76-0
  • MF: C12H10O4
  • MW: 218.205
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 378.0±30.0 °C at 760 mmHg
  • Melting Point: 92-94 °C(lit.)
  • Flash Point: 195.6±23.0 °C

Thymopoietin II: 32-35

Thymocartin (Thymopoietin II (32-35)) is the 32-35 fragment of the thymic factor (thymopoietin). Thymocartin has shown potential for immunodeficiency diseases research[1][2].

  • CAS Number: 85466-18-8
  • MF: C21H40N8O7
  • MW: 516.59200
  • Catalog: Inflammation/Immunology
  • Density: 1.45g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

AEZS-108

Zoptarelin doxorubicin (AEZS-108; AN-152) is a hybrid anticancer agent, containing Zoptarelin and Doxorubicin. Zoptarelin doxorubicin has been used to research targeting tumors expressing LHRH receptors. Zoptarelin doxorubicin abolishes tumor progression and induces remarkable apoptosis in vitro[1].

  • CAS Number: 139570-93-7
  • MF: C91H117N19O26
  • MW: 1893.014
  • Catalog: Cancer
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

2-Acetyl-3,5-dihydroxyphenylacetic acid

Curvulinic acid is a phytotoxic compound, has herbicidal activity[1].

  • CAS Number: 19053-94-2
  • MF: C10H10O5
  • MW: 210.18300
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Bentazon

Bentazone is a post-emergence herbicide used for selective control of broadleaf weeds and sedges in beans, rice, corn, peanuts, mint and others. It acts by interfering with photosynthesis[1].

  • CAS Number: 25057-89-0
  • MF: C10H12N2O3S
  • MW: 240.279
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 395.7±25.0 °C at 760 mmHg
  • Melting Point: 137-139°C
  • Flash Point: 193.1±23.2 °C

Soybean phospholipid

Lecithin is regarded as a safe, conventional phospholipid source. Phospholipids are reported to alter the fatty acid composition and microstructure of the membranes in animal cells.

  • CAS Number: 8002-43-5
  • MF: C42H80NO8P
  • MW: 758.060
  • Catalog: Others
  • Density: 1.0305 g/cm3 (20ºC)
  • Boiling Point: N/A
  • Melting Point: 236.1ºC
  • Flash Point: 57 °C

Regaloside D

Regaloside D is a phenylpropanoid isolated from Lilium Longiflorum[1].

  • CAS Number: 120601-66-3
  • MF: C18H24O10
  • MW: 400.37700
  • Catalog: Others
  • Density: 1.51±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

CRT

CRT, an iron peptide mimic, can bind to apo-transferrin (apo-Tf). CRT can be used to modify nanoparticles, and enhances drug delivery efficiency[1].

  • CAS Number: 2414254-70-7
  • MF: C37H64N12O12S2
  • MW: 933.11
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

cis,cis-muconic acid

cis,cis-Muconic acid, a metabolic intermediate of Klebsiella pneumonia, can be converted to adipic acid and terephthalic acid, which are important monomers of synthetic polymers. cis,cis-Muconic acid is also a biochemical material that can be used for the production of various plastics and polymers and is particularly gaining attention as an adipic acid precursor for the synthesis of nylon-6,6[1][2].

  • CAS Number: 1119-72-8
  • MF: C6H6O4
  • MW: 142.109
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 345.4±15.0 °C at 760 mmHg
  • Melting Point: 194-195ºC(lit.)
  • Flash Point: 176.9±16.9 °C

Pimroctakin (bovine)

Pimroctakin (bovine) is a IL-8 analogue[1].

  • CAS Number: 2559453-71-1
  • MF:
  • MW:
  • Catalog: Inflammation/Immunology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Clodronate Disodium

Clodronic acid (Clodronate) disodium salt, a first-generation bisphosphonate, is orally active osteoclastic bone resorption inhibitor. Clodronic acid disodium salt can be used in high bone turnover states, Paget’s disease and osteolytic bone metastases[1][2][3].

  • CAS Number: 22560-50-5
  • MF: CH2Cl2Na2O6P2
  • MW: 288.856
  • Catalog: Inflammation/Immunology
  • Density: 2.306g/cm3
  • Boiling Point: 474.7ºC at 760mmHg
  • Melting Point: >330ºC
  • Flash Point: 240.9ºC

Docusate sodium

Docusate Sodium is a laxative used to treat constipation, for constipation due to the use of opiates it maybe used with a stimulant laxative, can be taken by mouth or rectally.

  • CAS Number: 577-11-7
  • MF: C20H37NaO7S
  • MW: 444.558
  • Catalog: Others
  • Density: 1.1
  • Boiling Point: N/A
  • Melting Point: 173-179 °C(lit.)
  • Flash Point: 199ºC

Ethylenediaminetetraacetic acid (trisodium salt)

Ethylenediaminetetraacetic acid (EDTA) trisodium salt is used to bind metal ions in the practice of chelation therapy, for treating mercury and lead poisoning, used in a similar manner to remove excess iron from the body, for treating the complication of repeated blood transfusions, as would be applied to treat thalassaemia.

  • CAS Number: 150-38-9
  • MF: C10H13N2Na3O8
  • MW: 358.19
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 614.2ºC at 760 mmHg
  • Melting Point: 237 °C
  • Flash Point: 325.2ºC

Hosenkoside K

Hosenkoside K is a baccharane glycoside isolated from the seeds of impatiens balsamina.

  • CAS Number: 160896-49-1
  • MF: C54H92O25
  • MW: 1141.293
  • Catalog: Inflammation/Immunology
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

vitexin

Vitexin is a c-glycosylated flavone, and is found in various medicinal plants species such as Ficus deltoid and Spirodela polyrhiza. Vitexin has a wide range of pharmacological effects, including anti-oxidant, anti-cancer, anti-inflammatory, anti-hyperalgesic, and neuroprotective effects[1][2].

  • CAS Number: 3681-93-4
  • MF: C21H20O10
  • MW: 432.378
  • Catalog: Cancer
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 767.7±60.0 °C at 760 mmHg
  • Melting Point: 256-257ºC
  • Flash Point: 273.1±26.4 °C