Benzyl-PEG7-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Propargyl-PEG1-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
N'-Boc-N-(Gly-Oleoyl)-Lys is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
4-Boc-amino-22-dimethylbutyric acid is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Azetidin-3-ol hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azetidin-3-ol hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthes PROTAC.
TCO-PEG6-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Propargyl-PEG3-OCH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Bis-PEG13-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Boc-NH-PEG7-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Biotin-PEG7-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.
Pomalidomide-amido-C1-Br is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker. Pomalidomide-amido-C1-Br can be used to design a B-Raf PROTAC degrader PROTAC B-Raf degrader 1 (HY-111758). PROTAC B-Raf degrader 1 has anti-cancer activity[1].
Biotin-PEG3-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.
α-Lipoic acid-NHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Pentaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Fluorescein-PEG6-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Hydroxy-PEG1-(CH2)2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
THP-PEG8-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Azido-PEG3-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Azide-PEG3-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azide-PEG3-Tos is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].
Azido-PEG2-VHL is a multikinase degrader which can be used in the synthesis of PROTACs[1].
HO-PEG24-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Acid-PEG1-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
CRBN ligand-9 (Compound 4d) is a CRBN ligand (Ki: 8.9 μM). CRBN ligand-9 can be used for synthesis of PROTACs[1][2].
Bromoacetamido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Bromo-PEG2-bromide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Azido-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Azido-PEG3-phosphonic acid ethyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Propargyl-PEG4-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
AT6 is a PROTAC AT1 analogue, which is a highly selective bromodomain (Brd4) degrader.
Thalidomide-amido-PEG2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].