Chemsrc provides Others's classification. They are divided into Androgen Receptor, Aromatase, Estrogen Receptor/ERR, Progesterone Receptor, Thyroid Hormone Receptor, Others according to their Biological activity.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

H-Cys(pMeOBzl)-OH

H-Cys(pMeOBzl)-OH is a cysteine derivative[1].

  • CAS Number: 2544-31-2
  • MF: C11H15NO3S
  • MW: 241.307
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 417.6±45.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 206.4±28.7 °C

Influenza virus PA (46-54)

Influenza virus PA (46-54) is a biological active peptide. (HLA-A*0201 restricted epitope from influenza virus RNA polymerase subunit, PA (46-54).)

  • CAS Number: 318273-25-5
  • MF: C60H75N11O14S
  • MW: 1206.37
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

lucidin 3-O-beta-primveroside

Lucidin primeveroside (Lucidin 3-O-β-primeveroside) is an anthraquinone derivative present in madder root, which has been used as a coloring agent and food additive. Lucidin primeveroside can be metabolically converted to genotoxic compound Lucidin, which subsequently forms lucidin-specific DNA adducts[1][2].

  • CAS Number: 29706-59-0
  • MF: C26H28O14
  • MW: 564.49200
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: 210-212 °C
  • Flash Point: N/A

Eleutheroside D

Eleutheroside D is an active lignan isolated from the root of Eleutherococcus senticosus, has anti-inflammatory and hypoglycemic activities[1]. Eleutheroside D is an optical isomer of Eleutheroside E (HY-N0272)[2].

  • CAS Number: 79484-75-6
  • MF: C34H46O18
  • MW: 742.718
  • Catalog: Inflammation/Immunology
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 935.7±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 519.7±34.3 °C

Biotin Hydrazide

Biotin Hydrazide is a carbonyl-reactive biotinylation reagent, which is a carbonyl probe.

  • CAS Number: 66640-86-6
  • MF: C10H18N4O2S
  • MW: 258.341
  • Catalog: Biochemical Assay Reagents
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 633.1±40.0 °C at 760 mmHg
  • Melting Point: 245-247 °C
  • Flash Point: 336.7±27.3 °C

viFSP1

viFSP1 is a species-independent inhibitor of FSP1 that induces ferroptosis in FSP1-dependent cells. viFSP1 targets the highly conserved NAD(P)H binding pocket of FSP1 and directly inhibits FSP1. viFSP1 induces lipid peroxidation and has anticancer activity[1].

  • CAS Number: 951945-67-8
  • MF: C16H17N3O3S
  • MW: 331.39
  • Catalog: Ferroptosis
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Activated C Subunit

Activated C Subunit can be used in the synthesis of exon jumping oligomer conjugates. The oligomer conjugates complement selected target sites in the human anti-muscular atrophy protein gene and induce exon 51 jumping. It can be used for research of muscular dystrophy[1].

  • CAS Number: 1155373-31-1
  • MF: C37H37ClN5O5P
  • MW: 698.15
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

chlorthal-dimethyl

Chlorthal-dimethyl used as a pesticide intermediate.

  • CAS Number: 1861-32-1
  • MF: C10H6Cl4O4
  • MW: 331.964
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 422.0±40.0 °C at 760 mmHg
  • Melting Point: 155-156°C
  • Flash Point: 174.7±26.3 °C

Carviolin

Carviolin is a compound isolated from the mycelia of the ascomycete Neobulgaria pura. Carviolin inhibits the formation of appressoria in germinating conidia of Magnaporthe grisea on inductive (hydrophobic) surface. Carviolin exhibits moderate cytotoxic, but no antifungal, antibacterial, or phytotoxic activities[1].

  • CAS Number: 478-35-3
  • MF: C16H12O6
  • MW: 300.263
  • Catalog: Infection
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 630.0±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 241.3±25.0 °C

2,2'-Dichloro bisphenol A-d12

2,2'-Dichloro bisphenol A-d12 is the deuterium labeled 2,2'-Dichloro bisphenol A[1].

  • CAS Number: 2748525-32-6
  • MF: C15H2D12Cl2O2
  • MW: 309.25
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Ac-Ile-Glu-Thr-Asp-pNA

Ac-Ile-Glu-Thr-Asp-pNA is a substrate for caspase-8. Caspase-8 binds to and cleaves the Ile-Glu-Thr-Asp (IETD) peptide sequence to release p-nitroalinide, which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity[1].

  • CAS Number: 219138-21-3
  • MF: C27H38N6O12
  • MW: 638.624
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 1140.8±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 643.7±34.3 °C

Z-Pro-Pro-OH

Z-Pro-Pro is a peptide[1].

  • CAS Number: 7360-23-8
  • MF: C18H22N2O5
  • MW: 346.37800
  • Catalog: Others
  • Density: 1.345g/cm3
  • Boiling Point: 584.1ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 307.1ºC

Boc-3-(trifluoromethyl)-D-phenylalanine

Boc-D-Phe(3-CF3)-OH is a phenylalanine derivative[1].

  • CAS Number: 82317-82-6
  • MF: C15H18F3NO4
  • MW: 333.303
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 423.2±45.0 °C at 760 mmHg
  • Melting Point: 135-138 °C
  • Flash Point: 209.7±28.7 °C

LUF5771

LUF5771 is a potent allosteric recombinant luteinizing hormone (recLH) and Org 43553 inhibitor. LUF5771 is able to partially activate the LH receptor with low efficacy[1].

  • CAS Number: 1141802-49-4
  • MF: C24H23NO2
  • MW: 357.44
  • Catalog: Endocrinology
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Utreloxastat

Utreloxastat is a compound used for the research of the disorders including α-synucleinopathies, tauopathies, Amyotrophic lateral sclerosis (ALS), traumatic brain injury, and ischemic-reperfusion related injuries (patent WO2020081879A2, example A1)[1].

  • CAS Number: 1213269-96-5
  • MF: C18H28O2
  • MW: 276.41
  • Catalog: Neurological Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

CY5-YNE

CY5-YNE is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides.

  • CAS Number: 1345823-20-2
  • MF: C36H43N3O7S2
  • MW: 693.87
  • Catalog: Dye Reagents
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Copper gluconate

Copper(II) Gluconate is a non-toxic copper supplement aid. Copper(II) Gluconate is the copper salt of D-gluconic acid. Copper(II) Gluconate as a precursor catalyst that can be used in the photo-induced polymerisation of acrylates[1].

  • CAS Number: 527-09-3
  • MF: C12H22CuO14
  • MW: 453.841
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 673.6ºC at 760 mmHg
  • Melting Point: 155-157ºC
  • Flash Point: 375.2ºC

4-cumylphenol

4-Cumylphenol is a polycarbonate chain terminator. 4-Cumylphenol is widely used as a material for polycarbonate plastics, surfactants, fungicides and preservatives. 4-Cumylphenol also induces lipid accumulation in mouse adipocytes[1][2][3].

  • CAS Number: 599-64-4
  • MF: C15H16O
  • MW: 212.28700
  • Catalog: Others
  • Density: 1,115 g/cm3
  • Boiling Point: 335 °C
  • Melting Point: 72-75 °C
  • Flash Point: 160 °C

Decursinol

Decursinol, isolated from the roots of Angelica gigas, possesses antinociceptive effect with orally bioavailability. Decursinol possesses anti-tumor and anti-metastasis activity[1].

  • CAS Number: 23458-02-8
  • MF: C14H14O4
  • MW: 246.25900
  • Catalog: Cancer
  • Density: 1.293g/cm3
  • Boiling Point: 433.6ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 167.9ºC

Tetramethylthiuram sulfide

Tetramethylthiuram monosulfide (TMTM) is an active compound. Tetramethylthiuram monosulfide (TMTM) can be used for the research of rubber and various biochemical studies[1][2].

  • CAS Number: 97-74-5
  • MF: C6H12N2S3
  • MW: 208.368
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 260.9±23.0 °C at 760 mmHg
  • Melting Point: 107-111 °C(lit.)
  • Flash Point: 111.6±22.6 °C

Theasaponin E1

Theasaponin E1 is a tea saponin isolated from tea seeds. Theasaponin E1 exhibits potential antitumor activity against human tumor cell lines K562 and HL60. Theasaponin E1 also has quinone reductase (QR)-inducing activity and can act as an anti-tumor agent for cancer prevention[1].

  • CAS Number: 220114-28-3
  • MF: C59H90O27
  • MW: 1231.34
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

LS2265

LS2265 is a taurine derivative of fenofibrate and can induce proliferation of peroxisomes in liver cells of rats.

  • CAS Number: 72678-30-9
  • MF: C19H20ClNO6S
  • MW: 425.88300
  • Catalog: Metabolic Disease
  • Density: 1.371g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

CCW16

CCW16 is the covalent ligand for the E3 ubiquitin ligase RNF4. CCW16 can be used in the synthesis of protein degraders[1].

  • CAS Number: 2361138-33-0
  • MF: C22H20ClNO3
  • MW: 381.852
  • Catalog: Cancer
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 533.2±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 276.3±30.1 °C

Fmoc-Lys(ivDde)-OH

Fmoc-L-Lys(ivDde)-OH is a lysine derivative[1].

  • CAS Number: 204777-78-6
  • MF: C34H42N2O6
  • MW: 574.707
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 765.6±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 416.8±32.9 °C

Fmoc-D-phe(4-NO2)-OH

Fmoc-D-Phe(4-NO2)-OH is a phenylalanine derivative[1].

  • CAS Number: 177966-63-1
  • MF: C24H20N2O6
  • MW: 432.425
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 692.3±55.0 °C at 760 mmHg
  • Melting Point: 215-225ºC
  • Flash Point: 372.5±31.5 °C

3,4-Difluorophenylalanine

3,4-Difluorophenylalanine is a fluorinated peptide with gelation ability[1][2].

  • CAS Number: 32133-36-1
  • MF: C9H9F2NO2
  • MW: 201.170
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 311.9±42.0 °C at 760 mmHg
  • Melting Point: 237 °C
  • Flash Point: 142.5±27.9 °C

Saikosaponin S

Saikosaponin S is a natural product that can be isolated from Bupleurum scorzonerifolium[1].

  • CAS Number: 219690-93-4
  • MF: C48H78O18
  • MW: 943.12
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Cellhunt Green CMFDA [5-Chloromethylfluorescein Diacetate]

Green CMFDA (CMFDA) is a cell-permeable fluorescent probe that can be used a cell tracer. Green CMFDA can be cleaved by non-specific esterases common to living cells, producing a fluorescent compound, fluorescein, visible using a fluorescent microscope[1].

  • CAS Number: 136832-63-8
  • MF: C25H17ClO7
  • MW: 464.85100
  • Catalog: Others
  • Density: 1.49 g/cm3
  • Boiling Point: 657.5ºC at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 238.3ºC

5-Hydroxy-2-pyrrolidinone

5-Hydroxypyrrolidin-2-one (Compd 1) is a natural compound that can be isolated from Jatropha curcas[1].

  • CAS Number: 62312-55-4
  • MF: C4H7NO2
  • MW: 101.104
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 363.6±35.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 173.7±25.9 °C

(2R)-1-[2-[(3-Hydroxytricyclo[3.3.1.1(3,7)]dec-1-yl)amino]acetyl]-2-pyrrolidinecarbonitrile

(2R)-Vildagliptin is the inactive isomer of Vildagliptin (HY-14291), and can be used as an experimental control. Vildagliptin (LAF237) is a potent, stable, selective dipeptidyl peptidase IV (DPP-IV) inhibitor with an IC50 of 3.5 nM in human Caco-2 cells. Vildagliptin possesses excellent oral bioavailability and potent antihyperglycemic activity[1].

  • CAS Number: 1036959-27-9
  • MF: C17H25N3O2
  • MW: 303.40
  • Catalog: Metabolic Disease
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 531.3±50.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 275.1±30.1 °C