Saccharide is also called carbohydrate, consisting of carbon (C), hydrogen (H) and oxygen (O) atoms, usually with the empirical formula Cm(H2O)n. The saccharides are divided into four chemical groups: monosaccharides, disaccharides, oligosaccharides, and polysaccharides. Carbohydrates perform numerous roles in living organisms. Polysaccharides serve for the storage of energy (e.g. starch and glycogen) and as structural components. The 5-carbon monosaccharide ribose is an important component of coenzymes (e.g. ATP, FAD and NAD) and the backbone of the genetic molecule known as RNA. The related deoxyribose is a component of DNA. Saccharides and their derivatives include many other important biomolecules that play key roles in the immune system, fertilization, preventing pathogenesis, blood clotting, and development. A glycoside is a molecule in which a sugar is bound to another functional group via a glycosidic bond. Glycosides play numerous important roles in living organisms. Many plants store chemicals in the form of inactive glycosides. These can be activated by enzyme hydrolysis, which causes the sugar part to be broken off, making the chemical available for use. Many such plant glycosides are used as medications. In animals and humans, poisons are often bound to sugar molecules as part of their elimination from the body.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
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Autophagy >
Autophagy LRRK2 ULK Mitophagy
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Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
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GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
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JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
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Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Fructose

Fructose is a simple ketonic monosaccharide found in many plants, where it is often bonded to glucose to form the disaccharide sucrose.

  • CAS Number: 7660-25-5
  • MF: C6H12O6
  • MW: 180.156
  • Catalog: Cardiovascular Disease
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 551.7±50.0 °C at 760 mmHg
  • Melting Point: 100 - 110ºC
  • Flash Point: 301.5±26.6 °C

Uridine

Uridin is a glycosylated pyrimidine-analog containing uracil attached to a ribose ring (or more specifically, aribofuranose) via a β-N1-glycosidic bond.

  • CAS Number: 58-96-8
  • MF: C9H12N2O6
  • MW: 244.201
  • Catalog: Others
  • Density: 1.9±0.1 g/cm3
  • Boiling Point: 567.9±60.0 °C at 760 mmHg
  • Melting Point: 163-167 °C(lit.)
  • Flash Point: 297.2±32.9 °C

2'-deoxyuridine

2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxudine.

  • CAS Number: 951-78-0
  • MF: C9H12N2O5
  • MW: 228.202
  • Catalog: Infection
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 167-169 °C(lit.)
  • Flash Point: N/A

D-erythro-Neopterin

D-(+)-Neopterin, a catabolic product of guanosine triphosphate (GTM), serves as a marker of cellular immune system activation.

  • CAS Number: 2009-64-5
  • MF: C9H11N5O4
  • MW: 253.215
  • Catalog: Inflammation/Immunology
  • Density: 2.0±0.1 g/cm3
  • Boiling Point: 697.7ºC at 760mmHg
  • Melting Point: >232ºC (dec.)
  • Flash Point: 375.7ºC

D-(+)-Xylose

Xylose, a natural product, can be catalyzed into xylulose by xylose isomerase, and it is the key step for anaerobic ethanolic fermentation of xylose.

  • CAS Number: 58-86-6
  • MF: C5H10O5
  • MW: 150.130
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 415.5±38.0 °C at 760 mmHg
  • Melting Point: 148-158 ºC
  • Flash Point: 219.2±23.3 °C

2,3,5,4'-Tetrahydroxyl diphenylethylene-2-O-glucoside

2,3,4',5-tetrahydroxystilbene 2-O-D-glucoside isolats from the roots of Polygonum species, inhibits the formation of 5-HETE, HHT and thromboxane B2, although less strongly. [1]

  • CAS Number: 82373-94-2
  • MF: C20H22O9
  • MW: 406.383
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 715.0±60.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 386.2±32.9 °C

Glucoraphanin

Glucoraphanin, a natural glucosinolate found in cruciferous vegetable, is a stable precursor of the Nrf2 inducer sulforaphane, which possesses antioxidant, anti-inflammatory, and anti-carcinogenic effects.

  • CAS Number: 21414-41-5
  • MF: C12H23NO10S3
  • MW: 436.499
  • Catalog: Cancer
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

6-Biopterin

6-Biopterin (L-Biopterin), a pterin derivative, is a NO synthase cofactor.

  • CAS Number: 22150-76-1
  • MF: C9H11N5O3
  • MW: 237.215
  • Catalog: NO Synthase
  • Density: 1.9±0.1 g/cm3
  • Boiling Point: 563.4±60.0 °C at 760 mmHg
  • Melting Point: >210°C dec.
  • Flash Point: 294.5±32.9 °C

Forsythoside B

Forsythoside B is a phenylethanoid glycoside isolated from the leaves of Lamiophlomis rotata Kudo, a Chinese folk medicinal plant for treating inflammatory diseases and promoting blood circulation. Forsythoside B could inhibit TNF-alpha, IL-6, IκB and modulate NF-κB.

  • CAS Number: 81525-13-5
  • MF: C34H44O19
  • MW: 756.702
  • Catalog: TNF Receptor
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 1040.3±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 323.9±27.8 °C

Maltohexaose

Maltohexaose is a natural saccharide, and can be produced from amylose, amylopectin and whole starch.

  • CAS Number: 34620-77-4
  • MF: C36H62O31
  • MW: 990.85900
  • Catalog: Others
  • Density: 1.87g/cm3
  • Boiling Point: 1307.8ºC at 760mmHg
  • Melting Point: 204-206°C
  • Flash Point: 744.7ºC

Erythritol

meso-Erythritol is a sugar alcohol derived from fermenting the glucose of cornstarch, resulting in fewer calories and a less sweeter taste than regular sugar.

  • CAS Number: 149-32-6
  • MF: C4H10O4
  • MW: 122.120
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 330.0±0.0 °C at 760 mmHg
  • Melting Point: 118-120 °C(lit.)
  • Flash Point: 208.7±21.1 °C

Hyaluronic acid

Hyaluronic acid is a biopolymer composed of repeating units of disaccharides with various applications.

  • CAS Number: 9004-61-9
  • MF: (C14H21NO11)n
  • MW: 379.32 (monomer)
  • Catalog: Cancer
  • Density: 1.8±0.1 g/cm3
  • Boiling Point: 1274.4±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 724.5±34.3 °C

Timosaponin A1

Timosaponin A1 is a coprostane type steroidal saponin isolated from Rhizoma Anemarrhenae.

  • CAS Number: 68422-00-4
  • MF: C33H54O8
  • MW: 578.777
  • Catalog: Others
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 695.5±55.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 374.4±31.5 °C

D-Mannose

D-Mannose is a carbohydrate, which plays an important role in human metabolism, especially in the glycosylationof specific proteins.

  • CAS Number: 3458-28-4
  • MF: C6H12O6
  • MW: 180.156
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 527.1±50.0 °C at 760 mmHg
  • Melting Point: 133-140ºC
  • Flash Point: 286.7±26.6 °C

Anemarrhenasaponin I

Anemarrhenasaponin I, a traditional Chinese medicine, is isolated from Anemarrhena asphodeloides Bunge.

  • CAS Number: 163047-21-0
  • MF: C39H66O14
  • MW: 758.93
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Raffinose

D(+)-Raffinose pentahydrate (D-Raffinose pentahydrate) is a trisaccharide composed of galactose, glucose, and fructose that occurs naturally in a variety of vegetables and grains. D(+)-Raffinose pentahydrate is a functional oligosaccharide.

  • CAS Number: 17629-30-0
  • MF: C18H42O21
  • MW: 594.513
  • Catalog: Others
  • Density: N/A
  • Boiling Point: 884.8ºC at 760 mmHg
  • Melting Point: 78-80 °C
  • Flash Point: N/A

Saponins

Saponins are a class of chemical compounds of glycosides found in particular abundance in various plant species. In plants, saponins may serve as anti-feedants, and to protect the plant against microbes and fungi[1].

  • CAS Number: 8047-15-2
  • MF: C27H42O3
  • MW: 1645.293
  • Catalog: Inflammation/Immunology
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 158℃
  • Flash Point: N/A

1,2,3,4,6-O-Pentagalloylglucose

1,2,3,4,6-Penta-O-galloyl-β-D-glucopyranose is a gallotannin isolated from various plants. It suppressed interleukin (IL)-4 induced signal pathway in B cell, and inhibited IgE production partially caused by increasing a population of Treg cells in conjunction with Treg-inducing factors.

  • CAS Number: 14937-32-7
  • MF: C41H32O26
  • MW: 940.677
  • Catalog: Others
  • Density: 2.1±0.1 g/cm3
  • Boiling Point: 1365.7±65.0 °C at 760 mmHg
  • Melting Point: >250ºC dec.
  • Flash Point: 410.4±27.8 °C

Timosaponin BII

Timosaponin BII is an antioxidant and an anti-inflammatory agent.

  • CAS Number: 136656-07-0
  • MF: C45H76O19
  • MW: 921.073
  • Catalog: Cancer
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 1033.6±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 578.9±34.3 °C

Heparin

Heparin is a highly sulfated glycosaminoglycan,that is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule.

  • CAS Number: 9005-49-6
  • MF: C26H42N2O37S5
  • MW: 1134.93000
  • Catalog: Autophagy
  • Density: 2.18 g/cm3
  • Boiling Point: 644.9ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 343.8ºC

Tetrahydrobiopterin

Tetrahydrobiopterin is a cofactor of the aromatic amino acid hydroxylases enzymes and also acts as an essential cofactor for all nitric oxide synthase (NOS) isoforms.

  • CAS Number: 17528-72-2
  • MF: C9H15N5O3
  • MW: 241.25
  • Catalog: NO Synthase
  • Density: 1.89g/cm3
  • Boiling Point: 506.6ºC at 760mmHg
  • Melting Point: N/A
  • Flash Point: 260.2ºC

D-Galactose

D-Galactose is a natural aldohexose and C-4 epimer of glucose.

  • CAS Number: 59-23-4
  • MF: C6H12O6
  • MW: 180.156
  • Catalog: Neurological Disease
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 527.1±50.0 °C at 760 mmHg
  • Melting Point: 168-170 °C(lit.)
  • Flash Point: 286.7±26.6 °C

Hosenkoside A

Hosenkoside A is a baccharane glycoside isolated from the seeds of impatiens balsamina.

  • CAS Number: 156791-82-1
  • MF: C48H82O20
  • MW: 979.153
  • Catalog: Inflammation/Immunology
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 1075.9±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 604.5±34.3 °C

Casanthranol

Casanthranol is a concentrated mixture of anthranol glycosides from cascara sagrada (dried bark of Rhamnus p.) and used as a laxative in constipation and various medical conditions, stimulant laxative Casanthranol encourages bowel movements by acting on the intestinal wall to increase muscle contractions[1].

  • CAS Number: 8024-48-4
  • MF: C21H22O10
  • MW: 434.39300
  • Catalog: Metabolic Disease
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Desaminotyrosine

Desaminotyrosine is a microbially associated metabolite protecting from influenza through augmentation of type I interferon signaling.

  • CAS Number: 501-97-3
  • MF: C9H10O3
  • MW: 166.174
  • Catalog: Influenza Virus
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 352.4±17.0 °C at 760 mmHg
  • Melting Point: 129-131 °C(lit.)
  • Flash Point: 181.1±17.4 °C

Chaetocin

Chaetocin is a specific inhibitor of the histone methyltransferase (HMT) SU(VAR)3-9 with an IC50 of 0.6 μM for SU(VAR)3-9. It also inhibits thioredoxin reductase (TrxR) with an IC50 of 4 μM.

  • CAS Number: 28097-03-2
  • MF: C30H28N6O6S4
  • MW: 696.840
  • Catalog: Histone Methyltransferase
  • Density: 1.9±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Fagomine

Fagomine is a mild glycosidase inhibitor. The Ki of the iminosugar Fagomine is 4.8 μM, 39 μM, and 70 μM for Amyloglucosidase (A.niger), β-Glucosidase (bovine), and Isomaltase (yeast), respectively.

  • CAS Number: 53185-12-9
  • MF: C6H13NO3
  • MW: 147.172
  • Catalog: Metabolic Disease
  • Density: 1.3±0.1 g/cm3
  • Boiling Point: 315.4±42.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 170.5±18.5 °C