N-tert-Butoxycarbonyl-trans-4-hydroxy-D-proline is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-tert-Butoxycarbonyl-trans-4-hydroxy-D-proline is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1][2].
Benzyl-PEG3-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Biotin-C5-NHS Ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTAC Linker 9 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 9 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Azidoethyl-SS-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Propargyl-PEG8-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Benzyl-PEG6-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
L-Azidohomoalanine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
m-PEG6-(CH2)6-Phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Aeide-C1-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Tetrazine-Ph-acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
m-PEG3-Aminooxy is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
L-Homopropargylglycine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. L-homopropargylglycine hydrochloride is an amino acid analog of methionine containing an alkyne moiety that can undergo a classic click chemical reaction with azide containing Alexa Fluor[1][2].
TAMRA-PEG3-Azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Azido-PEG3-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG3-maleimide is also a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].
Methyl-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Propargyl-PEG17-methane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Fmoc-N-amido-PEG7-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
N-(m-PEG4)-N'-(DBCO-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Ald-Ph-PEG6-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
I-PEG6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Methylamino-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Fluorescein-PEG6-bis-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Hydroxy-PEG3-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Methyl 3-hydroxypropanoate is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Propargyl-PEG5-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Benzyl-PEG2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
NH2-PEG2-methyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Amino-PEG4-C1-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].