Chemsrc provides Others's classification, including all related biologically active compounds cover the research fields of cancer, neuroscience, immunology and other popular diseases, etc.


Anti-infection >
Arenavirus Bacterial CMV Enterovirus Filovirus Fungal HBV HCV HIV HSV Influenza Virus Parasite Reverse Transcriptase RSV SARS-CoV
Antibody-drug Conjugate >
ADC Cytotoxin ADC Linker Drug-Linker Conjugates for ADC PROTAC-linker Conjugate for PAC
Apoptosis >
Apoptosis Bcl-2 Family c-Myc Caspase DAPK Ferroptosis IAP MDM-2/p53 PKD RIP kinase Survivin Thymidylate Synthase TNF Receptor
Autophagy >
Autophagy LRRK2 ULK Mitophagy
Cell Cycle/DNA Damage >
Antifolate APC ATM/ATR Aurora Kinase Casein Kinase CDK Checkpoint Kinase (Chk) CRISPR/Cas9 Deubiquitinase DNA Alkylator/Crosslinker DNA-PK DNA/RNA Synthesis Eukaryotic Initiation Factor (eIF) G-quadruplex Haspin Kinase HDAC HSP IRE1 Kinesin LIM Kinase (LIMK) Microtubule/Tubulin Mps1 Nucleoside Antimetabolite/Analog p97 PAK PARP PERK Polo-like Kinase (PLK) PPAR RAD51 ROCK Sirtuin SRPK Telomerase TOPK Topoisomerase Wee1
Cytoskeleton >
Arp2/3 Complex Dynamin Gap Junction Protein Integrin Kinesin Microtubule/Tubulin Mps1 Myosin PAK
Epigenetics >
AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain HDAC Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MicroRNA PARP PKC Sirtuin Protein Arginine Deiminase
GPCR/G Protein >
5-HT Receptor Adenosine Receptor Adenylate Cyclase Adiponectin Receptor Adrenergic Receptor Angiotensin Receptor Bombesin Receptor Bradykinin Receptor Cannabinoid Receptor CaSR CCR CGRP Receptor Cholecystokinin Receptor CRFR CXCR Dopamine Receptor EBI2/GPR183 Endothelin Receptor GHSR Glucagon Receptor Glucocorticoid Receptor GNRH Receptor GPCR19 GPR109A GPR119 GPR120 GPR139 GPR40 GPR55 GPR84 Guanylate Cyclase Histamine Receptor Imidazoline Receptor Leukotriene Receptor LPL Receptor mAChR MCHR1 (GPR24) Melatonin Receptor mGluR Motilin Receptor Neurokinin Receptor Neuropeptide Y Receptor Neurotensin Receptor Opioid Receptor Orexin Receptor (OX Receptor) Oxytocin Receptor P2Y Receptor Prostaglandin Receptor Protease-Activated Receptor (PAR) Ras RGS Protein Sigma Receptor Somatostatin Receptor TSH Receptor Urotensin Receptor Vasopressin Receptor Melanocortin Receptor
Immunology/Inflammation >
Aryl Hydrocarbon Receptor CCR Complement System COX CXCR FLAP Histamine Receptor IFNAR Interleukin Related IRAK MyD88 NO Synthase NOD-like Receptor (NLR) PD-1/PD-L1 PGE synthase Salt-inducible Kinase (SIK) SPHK STING Thrombopoietin Receptor Toll-like Receptor (TLR) Arginase
JAK/STAT Signaling >
EGFR JAK Pim STAT
MAPK/ERK Pathway >
ERK JNK KLF MAP3K MAP4K MAPKAPK2 (MK2) MEK Mixed Lineage Kinase MNK p38 MAPK Raf Ribosomal S6 Kinase (RSK)
Membrane Transporter/Ion Channel >
ATP Synthase BCRP Calcium Channel CFTR Chloride Channel CRAC Channel CRM1 EAAT2 GABA Receptor GlyT HCN Channel iGluR Monoamine Transporter Monocarboxylate Transporter Na+/Ca2+ Exchanger Na+/HCO3- Cotransporter Na+/K+ ATPase nAChR NKCC P-glycoprotein P2X Receptor Potassium Channel Proton Pump SGLT Sodium Channel TRP Channel URAT1
Metabolic Enzyme/Protease >
15-PGDH 5 alpha Reductase 5-Lipoxygenase Acetyl-CoA Carboxylase Acyltransferase Adenosine Deaminase Adenosine Kinase Aldehyde Dehydrogenase (ALDH) Aldose Reductase Aminopeptidase Angiotensin-converting Enzyme (ACE) ATGL ATP Citrate Lyase Carbonic Anhydrase Carboxypeptidase Cathepsin CETP COMT Cytochrome P450 Dipeptidyl Peptidase Dopamine β-hydroxylase E1/E2/E3 Enzyme Elastase Enolase FAAH FABP Factor Xa Farnesyl Transferase Fatty Acid Synthase (FAS) FXR Glucokinase GSNOR Gutathione S-transferase HCV Protease Hexokinase HIF/HIF Prolyl-Hydroxylase HIV Integrase HIV Protease HMG-CoA Reductase (HMGCR) HSP Indoleamine 2,3-Dioxygenase (IDO) Isocitrate Dehydrogenase (IDH) Lactate Dehydrogenase LXR MAGL Mineralocorticoid Receptor Mitochondrial Metabolism MMP Nampt NEDD8-activating Enzyme Neprilysin PAI-1 PDHK PGC-1α Phosphatase Phosphodiesterase (PDE) Phospholipase Procollagen C Proteinase Proteasome Pyruvate Kinase RAR/RXR Renin ROR Ser/Thr Protease SGK Stearoyl-CoA Desaturase (SCD) Thrombin Tryptophan Hydroxylase Tyrosinase Xanthine Oxidase
Neuronal Signaling >
5-HT Receptor AChE Adenosine Kinase Amyloid-β Beta-secretase CaMK CGRP Receptor COMT Dopamine Receptor Dopamine Transporter FAAH GABA Receptor GlyT iGluR Imidazoline Receptor mAChR Melatonin Receptor Monoamine Oxidase nAChR Neurokinin Receptor Opioid Receptor Serotonin Transporter γ-secretase
NF-κB >
NF-κB IKK Keap1-Nrf2 MALT1
PI3K/Akt/mTOR >
Akt AMPK ATM/ATR DNA-PK GSK-3 MELK mTOR PDK-1 PI3K PI4K PIKfyve PTEN
PROTAC >
PROTAC E3 Ligase Ligand-Linker Conjugate Ligand for E3 Ligase PROTAC Linker PROTAC-linker Conjugate for PAC
Protein Tyrosine Kinase/RTK >
Ack1 ALK Bcr-Abl BMX Kinase Btk c-Fms c-Kit c-Met/HGFR Discoidin Domain Receptor DYRK EGFR Ephrin Receptor FAK FGFR FLT3 IGF-1R Insulin Receptor IRAK Itk PDGFR PKA Pyk2 ROS Src Syk TAM Receptor Trk Receptor VEGFR
Stem Cell/Wnt >
Casein Kinase ERK Gli GSK-3 Hedgehog Hippo (MST) JAK Notch Oct3/4 PKA Porcupine ROCK sFRP-1 Smo STAT TGF-beta/Smad Wnt YAP β-catenin γ-secretase
TGF-beta/Smad >
TGF-beta/Smad PKC ROCK TGF-β Receptor
Vitamin D Related >
VD/VDR
Others >
Androgen Receptor Aromatase Estrogen Receptor/ERR Progesterone Receptor Thyroid Hormone Receptor Others

Stachydrine

Stachydrine is a major constituent of Chinese herb leonurus heterophyllus sweet used to promote blood circulation and dispel blood stasis. Stachydrine can inhibit the NF-κB signal pathway.

  • CAS Number: 471-87-4
  • MF: C7H13NO2
  • MW: 143.18
  • Catalog: Others
  • Density: 1.1095 (rough estimate)
  • Boiling Point: 261.28°C (rough estimate)
  • Melting Point: 235°C
  • Flash Point: N/A

L(-)-Glutathione

Glutathione oxidized is produced by the oxidation of glutathione which is a major intracellular antioxidant and detoxifying agent.

  • CAS Number: 27025-41-8
  • MF: C20H32N6O12S2
  • MW: 612.631
  • Catalog: Others
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 976.3±75.0 °C at 760 mmHg
  • Melting Point: 178 °C (dec.)(lit.)
  • Flash Point: 544.3±37.1 °C

Cholesteryl behenate

Cholesteryl behenate is a standard in electrospray ionization tandem mass spectrometry for the analysis of cholesterol and cholesteryl esters.

  • CAS Number: 61510-09-6
  • MF: C49H88O2
  • MW: 709.222
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 711.0±39.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 385.1±14.6 °C

Norepinephrine

Norepinephrine is a peripheral vasoconstrictor by acting on alpha-adrenergic receptors.

  • CAS Number: 51-41-2
  • MF: C8H11NO3
  • MW: 169.178
  • Catalog: Parasite
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 442.6±40.0 °C at 760 mmHg
  • Melting Point: 220-230°C
  • Flash Point: 221.5±27.3 °C

Cocarboxylase

Thiamine pyrophosphate is the coenzyme form of Vitamin B1 and is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex.

  • CAS Number: 154-87-0
  • MF: C12H19ClN4O7P2S
  • MW: 460.767
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

DL-Norvaline

DL-Norvaline, a derivative of L-norvaline, L-norvaline is a non-competitive inhibitor of arginase.

  • CAS Number: 760-78-1
  • MF: C5H11NO2
  • MW: 117.146
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 222.9±23.0 °C at 760 mmHg
  • Melting Point: ≥300 °C (dec.)
  • Flash Point: 88.6±22.6 °C

Tyramine

Tyramine is an indirectly acting sympathomimetic amine that releases norepinephrine from presynaptic nerve terminals.

  • CAS Number: 51-67-2
  • MF: C8H11NO
  • MW: 137.179
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 275.1±23.0 °C at 760 mmHg
  • Melting Point: 160-162 °C(lit.)
  • Flash Point: 141.3±13.3 °C

Dodecanoylcarnitine

Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease.

  • CAS Number: 25518-54-1
  • MF: C19H37NO4
  • MW: 343.50100
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Bekanamycin

Bekanamycin is an aminoglycoside antibiotic.

  • CAS Number: 4696-76-8
  • MF: C18H37N5O10
  • MW: 483.514
  • Catalog: Bacterial
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 807.7±65.0 °C at 760 mmHg
  • Melting Point: 178-182° (dec)
  • Flash Point: 442.3±34.3 °C

1-​Arachidoyl-​sn-​glycero-​3-​phosphocholine

1-Arachidoyl-sn-glycero-3-phosphocholine is a lysophospholipid (LyP).

  • CAS Number: 108341-80-6
  • MF: C28H58NO7P
  • MW: 551.73600
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Sorbitol

D-Sorbitol is a sugar alcohol that is commonly used as a sugar substitute.Target: OthersD-Sorbitol occurs naturally and is also produced synthetically from glucose. The food industry uses D-sorbitol as an additive in the form of a sweetener, humectant, emulsifier, thickener, or dietary supplement. D-Sorbitol has also been found in cosmetics, paper, and pharmaceuticals. Naturally, D-sorbitol occurs widely in plants via photosynthesis, ranging from algae to higher order fruits of the family Rosaceae. From Wikipedia.

  • CAS Number: 50-70-4
  • MF: C6H14O6
  • MW: 182.172
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 494.9±0.0 °C at 760 mmHg
  • Melting Point: 98-100 °C (lit.)
  • Flash Point: >100°C

Calcium pantothenate

D-Pantothenic acid hemicalcium salt, a kind of water solublevitamin, can reduce the patulin content of the apple juice.IC50 value:Target:In vitro: In human dermal fibroblasts from three different donors, D-Pantothenic acid hemicalcium salt accelerates the wound healing process by increasing the number of migrating cells, their distance and hence their speed. In addition, cell division is increased and the protein synthesis changed [1].In vivo:

  • CAS Number: 137-08-6
  • MF: C9H16NO5.1/2Ca
  • MW: 238.27
  • Catalog: Others
  • Density: 1.266g/cm3
  • Boiling Point: 551.5ºC at 760 mmHg
  • Melting Point: 190 °C
  • Flash Point: 145 °C

1-Methyladenosine

1-Methyladenosine is an RNA modification originating essentially from two different reaction types, one catalyzed by enzymes and the other the result of the reaction of RNA with certain alkylating agents.

  • CAS Number: 15763-06-1
  • MF: C11H15N5O4
  • MW: 281.268
  • Catalog: Others
  • Density: 1.9±0.1 g/cm3
  • Boiling Point: 655.4±65.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 350.2±34.3 °C

Kynurenic acid

Kynurenic acid, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid is also a selective ligand of the GPR35 receptor.

  • CAS Number: 492-27-3
  • MF: C10H7NO3
  • MW: 189.167
  • Catalog: iGluR
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 358.4±42.0 °C at 760 mmHg
  • Melting Point: 275 °C (dec.)(lit.)
  • Flash Point: 170.5±27.9 °C

allantoin

Allantoin is a skin conditioning agent that promotes healthy skin, stimulates new and healthy tissue growth.

  • CAS Number: 97-59-6
  • MF: C4H6N4O3
  • MW: 158.115
  • Catalog: Imidazoline Receptor
  • Density: 1.7±0.1 g/cm3
  • Boiling Point: 478ºC
  • Melting Point: 230 °C (dec.)(lit.)
  • Flash Point: 230-234°C

4-Acetamidobutanoic acid

4-Acetamidobutanoic acid (N-acetyl GABA) is a γ-aminobutyric acid (GABA) derivative.

  • CAS Number: 3025-96-5
  • MF: C6H11NO3
  • MW: 145.15600
  • Catalog: GABA Receptor
  • Density: 1.133 g/cm3
  • Boiling Point: 405.4ºC at 760 mmHg
  • Melting Point: 128-131 °C
  • Flash Point: 199ºC

α-Cyclodextrin

α-Cyclodextrin is a multifunctional, soluble dietary fiber marketed for use as a fiber ingredient.

  • CAS Number: 10016-20-3
  • MF: C36H60O30
  • MW: 972.844
  • Catalog: Others
  • Density: 1.6±0.1 g/cm3
  • Boiling Point: 1410.8±60.0 °C at 760 mmHg
  • Melting Point: 278ºC
  • Flash Point: 807.1±32.9 °C

HYPOTAURINE

Hypotaurine (2-aminoethanesulfinic acid), an intermediate in taurine biosynthesis from cysteine in astrocytes, is an endogenous inhibitory amino acid of the glycine receptor.

  • CAS Number: 300-84-5
  • MF: C2H7NO2S
  • MW: 109.147
  • Catalog: Others
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 354.9±44.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 168.5±28.4 °C

Trichostatin A

Trichostatin A is a potent and specific inhibitor of HDAC class I/II, with an IC50 value of 1.8 nM for HDAC.

  • CAS Number: 58880-19-6
  • MF: C17H22N2O3
  • MW: 302.368
  • Catalog: HDAC
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: N/A
  • Melting Point: 141-143ºC
  • Flash Point: N/A

D-tryptophan

H-D-Trp-OH is a D-stereoisomer of tryptophan and occasionally found in naturally produced peptides such as the marine venom peptide.

  • CAS Number: 153-94-6
  • MF: C11H12N2O2
  • MW: 204.225
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 447.9±35.0 °C at 760 mmHg
  • Melting Point: 282-285ºC
  • Flash Point: 224.7±25.9 °C

Stearoylcarnitine

Stearoylcarnitine is a fatty ester lipid molecule.

  • CAS Number: 25597-09-5
  • MF: C25H49NO4
  • MW: 427.66
  • Catalog: Others
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Palmitoylethanolamide

AM 3112 is an active endogenous compound which can used for preventing virus infection of the respiratory tract.

  • CAS Number: 544-31-0
  • MF: C18H37NO2
  • MW: 299.492
  • Catalog: Others
  • Density: 0.9±0.1 g/cm3
  • Boiling Point: 461.5±28.0 °C at 760 mmHg
  • Melting Point: 99 °C
  • Flash Point: 232.9±24.0 °C

D-glutamine

D-Glutamine is a cell-permeable D type stereoisomer of Glutamine.

  • CAS Number: 5959-95-5
  • MF: C5H10N2O3
  • MW: 146.145
  • Catalog: Autophagy
  • Density: 1.5±0.1 g/cm3
  • Boiling Point: 353.5±52.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 167.6±30.7 °C

3-hydroxybutyric acid

3-Hydroxybutyric acid is a butyric acid substituted with a hydroxyl group in the beta or 3 position.

  • CAS Number: 300-85-6
  • MF: C4H8O3
  • MW: 104.104
  • Catalog: Others
  • Density: 1.2±0.1 g/cm3
  • Boiling Point: 269.2±0.0 °C at 760 mmHg
  • Melting Point: 174-175℃
  • Flash Point: 121.0±19.1 °C

Gastric Inhibitory Polypeptide (human)

Gastric Inhibitory Peptide (GIP), human is thought to act as an inhibitor of gastric functions.

  • CAS Number: 100040-31-1
  • MF: C226H338N60O66S
  • MW: 4983.53
  • Catalog: Peptides
  • Density: N/A
  • Boiling Point: N/A
  • Melting Point: N/A
  • Flash Point: N/A

Propyl paraben

Propylparaben is an antimicrobial agent, preservative, flavouring agent.

  • CAS Number: 94-13-3
  • MF: C10H12O3
  • MW: 180.201
  • Catalog: Bacterial
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 294.3±13.0 °C at 760 mmHg
  • Melting Point: 95-98 °C(lit.)
  • Flash Point: 124.6±12.6 °C

Pyridoxine

Pyridoxine is a pyridine derivative. Pyridoxine exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.

  • CAS Number: 65-23-6
  • MF: C8H11NO3
  • MW: 169.178
  • Catalog: Keap1-Nrf2
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 491.9±40.0 °C at 760 mmHg
  • Melting Point: 159-162ºC
  • Flash Point: 251.3±27.3 °C

Erianin

Erianin, often used as an antipyretic and analgesic agent, could inhibit IDO-induced tumor angiogenesis.

  • CAS Number: 95041-90-0
  • MF: C18H22O5
  • MW: 318.364
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 439.1±40.0 °C at 760 mmHg
  • Melting Point: N/A
  • Flash Point: 219.4±27.3 °C

L-Valine

L-Valine is one of 20 proteinogenic amino acids. L-Valine is an essential amino acid.

  • CAS Number: 72-18-4
  • MF: C5H11NO2
  • MW: 117.146
  • Catalog: Others
  • Density: 1.1±0.1 g/cm3
  • Boiling Point: 213.6±23.0 °C at 760 mmHg
  • Melting Point: 315ºC
  • Flash Point: 83.0±22.6 °C

Columbin

Columbin is a diterpenoid furanolactone with anti-inflammation activity.

  • CAS Number: 546-97-4
  • MF: C20H22O6
  • MW: 358.385
  • Catalog: Others
  • Density: 1.4±0.1 g/cm3
  • Boiling Point: 565.9±50.0 °C at 760 mmHg
  • Melting Point: 190-191ºC
  • Flash Point: 296.0±30.1 °C