NH2-PEG3-C6-Cl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PEG7-O-Ms is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
m-PEG5-2-methylacrylate is a PEG- and Alkyl/ester-based PROTAC linker can be used in the synthesis of PROTACs[1].
(2-Pyridyldithio)-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Cbz-NH-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Cereblon inhibitor 1, an isoindoline derivative, is a cereblon E3 ubiquitin ligase modulating drug. Cereblon inhibitor 1 has the potential for cancer research[1].
Azido-PEG6-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG6-alcohol is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].
Boc-NH-PEG8-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Me-PEG4-Me is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Thalidomide-NH-amido-C4-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
Mal-NH2 (TFA) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Methyltetrazine-PEG4-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
N-(Azide-PEG3)-N'-(PEG4-acid)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Bromoacetamido-PEG3-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Biotin-PEG6-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
TCO-PEG3-amide-C3-triethoxysilane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Ethyl acetate-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
HO-PEG14-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
HO-PEG18-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Thiol-PEG8-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
THP-CH3-ethyl propionate is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Thalidomide-NH-C2-PEG3-OH is an E3 ligase ligand-linker conjugate that incorporates Thalidomide based cereblon ligand and a linker used for PROTAC BCL-XL degrader XZ739[1].
PROTAC IRAK4 degrader-3 is a PROTAC-induced IRAK4 degrader[1].
Biotin-PEG6-Thalidomide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Pomalidomide-PEG1-azide is a E3 ligase lgand-linker conjugate. Pomalidomide-PEG1-azide incorporates the Pomalidomide based cereblon ligand and a linker. Pomalidomide-PEG1-azide can be used to design a PROTAC BRD4 Degrader-1 (HY-133131)[1].
N-(m-PEG4)-N'-(biotin-PEG3)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Ac4GlcNAlk is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Thalidomide-5-propoxyethanamine is the Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein[1].
ND1-YL2 is a PROTAC that selectively degrades SRC-1 via the N-degron pathway. ND1-YL2 significantly inhibits cancer invasion and migration in vitro and in vivo. ND1-YL2 can be used in cancer research[1].
Methylamino-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].